Tyrosine Nitration Impairs Mammalian Aldolase A Activity* [PDF]
Molecular & Cellular Proteomics, 2004 Protein tyrosine nitration increases in vivo as a result of oxidative stress and is elevated in numerous inflammatory-associated diseases. Mammalian fructose-1,6-bisphosphate aldolases are tyrosine nitrated in lung epithelial cells and liver, as well as ...
T. Koeck +5 more
semanticscholar +3 more sources
Identification of dehydrogenase, hydratase, and aldolase responsible for the propionyl residue removal in degradation of cholic acid C-17 side chain in Comamonas testosteroni TA441 [PDF]
Microbiology SpectrumBacterial steroid degradation is gaining attention for its diverse roles, such as Mycobacterium tuberculosis’s reliance on the degradation of the C17 side chain of cholesterol for survival in host environments.
Masae Horinouchi
doaj +2 more sources
A potential role for the interaction of Wolbachia surface proteins with the Brugia malayi glycolytic enzymes and cytoskeleton in maintenance of endosymbiosis. [PDF]
PLoS Neglected Tropical Diseases, 2013 The human filarial parasite Brugia malayi harbors an endosymbiotic bacterium of the genus Wolbachia. The Wolbachia represent an attractive target for the control of filarial induced disease as elimination of the bacteria affects molting, reproduction and
Elena Melnikow +6 more
doaj +6 more sources
ADAPTOR PROTEIN Ruk/CIN85 PARTICIPATES IN THE METABOLIC CONTROL OF HUMAN BREAST ADENOCARCINOMA MCF-7 CELLS [PDF]
Biotechnologia Acta, 2022 Aim. To determine the role of Ruk/CIN85 in the control of breast adenocarcinoma cells metabolism, we performed systemic analysis of the activity levels/content of key enzymes/components of glycolysis and oxidative phosphorylation using as a model the ...
R. S. Korshun +5 more
doaj +1 more source
Threonine aldolase-catalyzed stereoselective radical α-alkylation of amino acids. [PDF]
Methods EnzymolKe T, Yang Y.
europepmc +3 more sources
Human aldolase A deficiency associated with a hemolytic anemia: thermolabile aldolase due to a single base mutation. [PDF]
Proceedings of the National Academy of Sciences, 1987 Fructose-1,6-bisphosphate aldolase A (fructose-bisphosphate aldolase; EC 4.1.2.13) deficiency is an autosomal recessive disorder associated with hereditary hemolytic anemia. To clarify the molecular mechanism of the deficiency at the nucleotide level, we have cloned aldolase A cDNA from a patient's poly(A)+ RNA that was expressed in cultured ...
Hiroyuki Kishi +5 more
semanticscholar +3 more sources
Structure and expression of mouse aldolase genes. Brain-specific aldolase C amino acid sequence is closely related to aldolase A. [PDF]
European Journal of Biochemistry, 1986 Brain-specific aldolase C amino acid sequence (greater than 75% of the coding region) was determined for the first time. Two cDNA clones, pAM1 and pAM2, were identified, from a mouse brain library, by using human aldolase B cDNA as a probe. The larger one, pAM2, identified as a cDNA for aldolase C, has been completely sequenced and covers the 5 ...
G. Paolella +4 more
semanticscholar +7 more sources
Scientific Reports, 2023 Glucose metabolism and DNA repair are fundamental cellular processes frequently dysregulated in cancer. In this study, we define a direct role for the glycolytic Aldolase A (ALDOA) protein in DNA double-strand break (DSB) repair.
Thais Sobanski +10 more
semanticscholar +1 more source
Human aldolase A gene. Structural organization and tissue-specific expression by multiple promoters and alternate mRNA processing. [PDF]
European Journal of Biochemistry, 1988 P. Izzo +5 more
semanticscholar +2 more sources