Results 41 to 50 of about 21,208,579 (315)

Toxoplasma gondii Syntaxin 6 is required for vesicular transport between endosomal-like compartments and the Golgi Complex [PDF]

, 2013
Apicomplexans are obligate intracellular parasites that invade the host cell in an active process that relies on unique secretory organelles (micronemes, rhoptries and dense granules) localized at the apical tip of these highly polarized eukaryotes ...
Clucas, Caroline, Ferguson, David J., Jackson, Allison J., Mamczur, Nicola J., Meissner, Markus   +4 more
core   +1 more source

Identification of aldolase A as a potential diagnostic biomarker for colorectal cancer based on proteomic analysis using formalin-fixed paraffin-embedded tissue

Tumor Biology, 2016
Colorectal cancer (CRC) is one of the most common cancers worldwide, and many patients are already at an advanced stage when they are diagnosed. Therefore, novel biomarkers for early detection of colorectal cancer are required.
Tetsushi Yamamoto, M. Kudo, W. Peng, H. Takata, Hideki Takakura, Kiyoshi Teduka, T. Fujii, K. Mitamura, A. Taga, E. Uchida, Z. Naito   +10 more
semanticscholar   +1 more source

Hereditary Fructose Intolerance Diagnosed in Adulthood

Gut and Liver, 2021
Hereditary fructose intolerance (HFI) is an autosomal recessive disorder caused by a mutation in the aldolase B gene. HFI patients exhibit nausea, vomiting, abdominal pain, hypoglycemia, and elevated liver enzymes after dietary fructose exposure. Chronic
Min Soo Kim, Jin Soo Moon, Man Jin Kim, Moon-Woo Seong, Sung Sup Park, Jae Sung Ko   +5 more
doaj   +1 more source

Fructose metabolism in Chromohalobacter salexigens: interplay between the Embden–Meyerhof–Parnas and Entner–Doudoroff pathways [PDF]

, 2019
Background The halophilic bacterium Chromohalobacter salexigens metabolizes glucose exclusively through the Entner–Doudoroff (ED) pathway, an adaptation which results in inefficient growth, with significant carbon overflow, especially at low salinity ...
Argandoña Bertrán, Montserrat, Bernal, Vicente, Borges, Nuno, Castaño Cerezo, Sara, Csonka, Laszlo N., Cánovas, Manuel, Gonçalves, Luís G., Goodner, Bradley W., Nieto Gutiérrez, Joaquín José, Pagán, Juan P., Pastor, José M., Reynolds, Kathryn A., Vargas Macías, Carmen   +12 more
core   +1 more source

Binding of Aldolase and Glyceraldehyde-3-Phosphate Dehydrogenase to the Cytoplasmic Tails of Plasmodium falciparum Merozoite Duffy Binding-Like and Reticulocyte Homology Ligands

mBio, 2012
Invasion of erythrocytes by Plasmodium falciparum requires a connection between the cytoplasmic tail of the parasite’s ligands for its erythrocyte receptors and the actin-myosin motor of the parasite.
Ipsita Pal-Bhowmick, John Andersen, Prakash Srinivasan, David L. Narum, Jürgen Bosch, Louis H. Miller   +5 more
doaj   +1 more source

Glycolytic biomarkers predict transformation in patients with follicular lymphoma.

PLoS ONE, 2020
Follicular lymphoma (FL) is an indolent neoplasia comprising approximately 20% of lymphomas. FL is generally considered incurable, with a median survival exceeding 10 years.
Ida Monrad, Charlotte Madsen, Kristina Lystlund Lauridsen, Bent Honoré, Trine Lindhardt Plesner, Stephen Hamilton-Dutoit, Francesco d'Amore, Maja Ludvigsen   +7 more
doaj   +1 more source

Redesigning Aldolase Stereoselectivity by Homologous Grafting. [PDF]

PLoS ONE, 2016
The 2-deoxy-d-ribose-5-phosphate aldolase (DERA) offers access to highly desirable building blocks for organic synthesis by catalyzing a stereoselective C-C bond formation between acetaldehyde and certain electrophilic aldehydes.
Carolin Bisterfeld, Thomas Classen, Irene Küberl, Birgit Henßen, Alexander Metz, Holger Gohlke, Jörg Pietruszka   +6 more
doaj   +1 more source

Corrigendum: Unmet Psychosocial Needs of Patients Newly Diagnosed with Ulcerative Colitis: Results from the Nationwide Prospective Cohort Study in Korea

Gut and Liver, 2021
Hereditary fructose intolerance (HFI) is an autosomal recessive disorder caused by a mutation in the aldolase B gene. HFI patients exhibit nausea, vomiting, abdominal pain, hypoglycemia, and elevated liver enzymes after dietary fructose exposure. Chronic
Jung Rock Moon, Chang Kyun Lee, Sung Noh Hong, Jong Pil Im, Byong Duk Ye, Jae Myung Cha, Sung-Ae Jung, Kang-Moon Lee, Dong Il Park, Yoon Tae Jeen, Young Sook Park, Jae Hee Cheon, Hyesung Kim, BoJeong Seo, Youngdoe Kim, Hyo Jong Kim, the MOSAIK study group of the Korean Association for the Study of Intestinal Diseases (KASID)   +16 more
doaj   +1 more source

Fructose-Bisphosphate Aldolase A Is a Potential Metastasis-Associated Marker of Lung Squamous Cell Carcinoma and Promotes Lung Cell Tumorigenesis and Migration

PLoS ONE, 2014
Fructose-bisphosphate aldolase A (ALDOA) is a key enzyme in glycolysis and is responsible for catalyzing the reversible conversion of fructose-1,6-bisphosphate to glyceraldehydes-3-phosphate and dihydroxyacetone phosphate.
S. Du, Zhu-zhu Guan, Lihong Hao, Yang Song, Lan Wang, Linlin Gong, Lu Liu, Xiaoyu Qi, Z. Hou, S. Shao   +9 more
semanticscholar   +1 more source

Plasma membrane association by N-acylation governs PKG function in Toxoplasma gondii [PDF]

, 2017
Cyclic GMP (cGMP)-dependent protein kinase (protein kinase G [PKG]) is essential for microneme secretion, motility, invasion, and egress in apicomplexan parasites, However, the separate roles of two isoforms of the kinase that are expressed by some ...
Brown, Kevin M, Long, Shaojun, Sibley, L. David   +2 more
core   +2 more sources