Archaeal Fructose-1,6-bisphosphate Aldolases Constitute a New Family of Archaeal Type Class I Aldolase [PDF]
Fructose-1,6-bisphosphate (FBP) aldolase activity has been detected previously in several Archaea. However, no obvious orthologs of the bacterial and eucaryal Class I and II FBP aldolases have yet been identified in sequenced archaeal genomes. Based on a recently described novel type of bacterial aldolase, we report on the identification and molecular ...
Siebers, B. +6 more
openaire +4 more sources
Intolerância hereditária à frutose.
Hereditary fructose intolerance (HFI) is a rare autosomal recessive, metabolic disorder, that results from a deficiency of aldolase B (fructose-biphosphate aldolase) in the liver, kidney and intestine.
A I Lopes +4 more
doaj +1 more source
Pasteurella multocida sialic acid aldolase: a promising biocatalyst [PDF]
Sialic acid aldolases or N-acetylneuraminate lyases (NanAs) catalyze the reversible aldol cleavage of N-acetylneuraminic acid (Neu5Ac) to form pyruvate and N-acetyl-D: -mannosamine (ManNAc). A capillary electrophoresis assay was developed to directly characterize the activities of NanAs in both Neu5Ac cleavage and Neu5Ac synthesis directions. The assay
Yanhong Li +7 more
semanticscholar +3 more sources
Multifunctional Fructose 1,6-Bisphosphate Aldolase as a Therapeutic Target
Fructose 1,6-bisphosphate aldolase is a ubiquitous cytosolic enzyme that catalyzes the fourth step of glycolysis. Aldolases are classified into three groups: Class-I, Class-IA, and Class-II; all classes share similar structural features but low amino ...
David B. Pirovich +2 more
doaj +1 more source
Disease spectrum of myopathies with elevated aldolase and normal creatine kinase
Elevation of serum creatine kinase (CK) or hyperCKemia is considered a biological marker of myopathies. However, selective elevation of serum aldolase with normal CK has been reported in a few myopathies, including dermatomyositis, immune‐mediated ...
Pannathat Soontrapa +4 more
semanticscholar +1 more source
Long-term cultivation of two diploid epithelial cell lines derived from normal rat liver cells [PDF]
To obtain a useful rat liver cell line for in vitro carcinogenesis, two rat diploid epithelial cell lines were established from a 7-day-old male rat by the repeated colonial clone method.
Masuji, Hiroshi +2 more
core +1 more source
Characterization, cloning and immunogenicity of antigens released by lung-stage larvae of Schistosoma mansoni [PDF]
Lung-stage schistosomula are the target of protective immunity in mice vaccinated with attenuated cercariae of Schistosoma mansoni. Therefore, proteins present at this developmental stage, and in particular those which are secreted, are a potential ...
Coulson, P S, Harrop, R, Wilson, R A
core +1 more source
A Functional Arginine Residue in Rabbit‐Muscle Aldolase [PDF]
Rabbit muscle aldolase is irreversibly modified by the arginine‐selective α‐dicarhonvi, phenylglyoxal loss of activity correlating with the unique modifications of one arginine residue per subunit, as determined by amino acid analysis, and [7‐14C]phenylglyoxal incorporation.
R R, Lobb +3 more
openaire +2 more sources
Gene transcription in eukaryotes is modulated by the coordinated recruitment of specific transcription factors and chromatin-modulating proteins. Indeed, gene activation and/or repression is/are regulated by histone methylation status at specific ...
Elena Cesaro +7 more
semanticscholar +1 more source
Development of 'Redox Arrays' for identifying novel glutathionylated proteins in the secretome [PDF]
Proteomics techniques for analysing the redox status of individual proteins in complex mixtures tend to identify the same proteins due to their high abundance.
Bottazzi, Barbara +6 more
core +1 more source

