Results 1 to 10 of about 1,348 (116)
Observations of reaction intermediates and the mechanism of aldose-ketose interconversion by D-xylose isomerase. [PDF]
Proceedings of the National Academy of Sciences, 1990 Crystallographic studies of D-xylose isomerase (D-xylose ketol-isomerase, EC 5.3.1.5) incubated to equilibrium with substrate/product mixtures of xylose and xylulose show electron density for a bound intermediate. The accumulation of this bound intermediate shows that the mechanism is a non-Michaelis type. Carrell et al. [Carrell, H. L., Glusker, J. P.,
C A, Collyer, D M, Blow
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Methionine Salvage Enzyme Uses a Unique Mechanism to Overcome a Challenging Aldose-Ketose Isomerization. [PDF]
J Am Chem SocThe enzyme-catalyzed interconversion of aldoses and ketoses historically involves one of two mechanisms, both of which require an aldehyde form of the substrate.
Ubayawardhana ST +4 more
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Journal of Molecular Biology, 1990 The active site and mechanism of D-xylose isomerase have been probed by determination of the crystal structures of the enzyme bound to various substrates, inhibitors and cations. Ring-opening is an obligatory first step of the reaction and is believed to be the rate-determining step for the aldose to ketose conversion. The structure of a complex with a
C A, Collyer, K, Henrick, D M, Blow
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Journal of the American Society for Mass Spectrometry, 1993 Julie A Leary, J A Leary, Ya-Jun Zheng
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Journal of Applied Glycoscience, 2023 This review discusses sugar isomerization with organogermanium compounds. Organogermanium compounds markedly increase the aldose-ketose (glucose-fructose or lactose-lactulose) isomerization ratio, double the initial reaction rate, and significantly ...
Takae Nagasawa +2 more
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Journal of Biological Chemistry, 1996 The lpcA locus has been identified in Escherichia coli K12 novobiocin-supersensitive mutants that produce a short lipopolysaccharide (LPS) core which lacks glyceromannoheptose and terminal hexoses.
J. Brooke, M. Valvano
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Journal of Applied Glycoscience, 2021 We previously demonstrated that the organogermanium compound 3-(trihydroxygermyl)propanoic acid (THGP) enhances the enzymatic and alkaline isomerization of an aldose to a ketose through cis-diol complex formation by multiple mechanisms.
Katsuyuki Sato +2 more
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Methylthio-D-ribose-1-Phosphate Isomerase Uses a Novel Mechanism for Aldose–Ketose Isomerization
The enzyme-catalyzed interconversion of aldoses and ketoses historically involves one of two mechanisms, both of which require an aldehyde form of the substrate. Methylthio-D-ribose-1-phosphate (MTR1P) isomerase (MtnA), which functions in the methionine-salvage pathway, poses a challenge to this canon because its substrate cannot readily access such a ...
Andrew Murkin, Subashi Ubayawardhana
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eFood, 2020 Advanced Glycation End Products (AGEs) could be formed with a -dicarbonyl compounds as intermediates; however, simultaneous determination of AGES as well as their precursors and intermediates have rarely been mentioned, so as to investigate the reaction.
Chaoyi Xue +6 more
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Pathways of carbohydrate metabolism in microorganisms.
Bacteriological reviews, 1955 I. C. Gunsalus, B. Horecker, W. Wood
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