Results 231 to 240 of about 161,997 (305)

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò   +18 more
wiley   +1 more source

Case Report: A case of pediatric reninoma and literatures review. [PDF]

open access: yesFront Med (Lausanne)
Zhao W   +6 more
europepmc   +1 more source

The endocrine product of renal (preglomerular) contractile pericytes depends on prolyl‐4‐hydroxylases 2 and 3

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Preglomerular pericyte‐like SMMHC+ vascular smooth muscle cells (VSMCs) display marked endocrine plasticity. Hypotension caused by salt depletion and angiotensin‐converting enzyme (ACE) inhibition induces a reversible transformation of these VSMCs toward an endocrine state that produces renin.
Bettina K. M. Firmke   +4 more
wiley   +1 more source

Prospective randomised trial comparing thermal ablation With laparoscopic Adrenalectomy as an alternatiVE treatment for unilateral asymmetric primary aldosteronism: a protocol for the WAVE trial. [PDF]

open access: yesBMJ Open
Laycock K   +30 more
europepmc   +1 more source

Comprehensive Quantitative Urinary Steroid Profiling of 29 Steroids Using Liquid Chromatography‐Tandem Mass Spectrometry

open access: yesAnalytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT Steroids are critical for numerous physiological processes; disruption in their metabolism is associated with numerous endocrine disorders. Steroid quantification is essential to improve the understanding and diagnosis of these pathologies. Historically, urinary steroid profiling has been performed using low‐throughput gas chromatography mass ...
Joshua T. Bain   +4 more
wiley   +1 more source

The myth of the metabolic baseline: sleep–wake cycles undermine a foundational assumption in organismal biology

open access: yesBiological Reviews, Volume 101, Issue 3, Page 1491-1510, June 2026.
ABSTRACT Basal and standard metabolic rate (BMR and SMR) are cornerstones of physiological ecology and are assumed to be relatively fixed intrinsic properties of organisms that represent the minimum energy required to sustain life. However, this assumption is conceptually flawed. Many core maintenance processes underlying SMR are temporally partitioned
Helena Norman   +4 more
wiley   +1 more source

Unmasking Early Cardiac Fibrosis in Sarcoidosis: The Role of Plasma Aldosterone and Cardiac MRI. [PDF]

open access: yesJ Clin Med
Giallafos E   +18 more
europepmc   +1 more source

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