Results 41 to 50 of about 232,884 (341)

Twenty-Four-Hour Urinary Aldosterone Predicts Inappropriate Left Ventricular Mass Index in Patients with Primary Aldosteronism

The Scientific World Journal, 2013
Objective. Primary aldosteronism (PA) is associated with inappropriate left ventricular hypertrophy (LVH) in relation to a given gender and body size. There is no ideal parameter to predict the presence of LVH or inappropriate LVH in patients with PA. We
Chi-Sheng Hung, Yi-Lwun Ho, Yi-Yao Chang, Vin-Cent Wu, Xue-Ming Wu, Jen-Kuang Lee, Shih-Chieh Chueh, Yen-Hung Lin, Yuan-Shian Changh, Shao-Yu Yang, Ya-Hui Hu, Ming-Jai Sui, Ming-Fong Chen, Kwan-Dun Wu   +13 more
doaj   +1 more source

Short-term heat acclimation is effective and may be enhanced rather than impaired by dehydration [PDF]

, 2014
Most heat acclimation data are from regimes longer than 1 week, and acclimation advice is to prevent dehydration. Objectives: We hypothesized that (i) short-term (5-day) heat acclimation would substantially improve physiological strain and exercise ...
Armstrong, Armstrong, Ashenden, Bergeron, Borg, Brandenberger, Brandenberger, Brengelmann, Buono, Buono, Burge, Casa, Casa, Cheung, Convertino, Convertino, Costill, Cotter, Creasy, Dill, Engell, Epstein, Fellman, Fleming, Fortney, Francesconi, Gabai, Gagge, Garrett, Garrett, Garrett, Gisolfi, Gonzalez-Alonso, Gore, Goulet, Graichen, Greenleaf, Harrison, Harrison, Hopkins, Hopper, Horowitz, Horowitz, Hurwitz, Joyner, Judelson, Kay, Kee-Bum, Kenefick, Lorenzo, Maresh, Marshall, McClung, McConell, Merry, Morris, Moseley, Nadel, Nagashima, Nielsen, Njemini, Noakes, Nose, Oehler, Okazaki, Okazaki, Patterson, Patterson, Patterson, Racinais, Ramanathan, Sawka, Sawka, Sawka, Sawka, Schwimmer, Scoon, Senay, Shido, Shvartz, Strydom, Tetievsky, Turk, Wall, Weller, Witney, Wyndham   +86 more
core   +1 more source

Genetic Characteristics of Aldosterone-Producing Adenomas in Blacks

HYPERTENSION, 2019
Somatic mutations have been identified in aldosterone-producing adenomas (APAs) in genes that include KCNJ5, ATP1A1, ATP2B3, and CACNA1D. Based on independent studies, there appears to be racial differences in the prevalence of somatic KCNJ5 mutations ...
K. Nanba, K. Omata, C. Gomez-Sanchez, C. Stratakis, A. Demidowich, M. Suzuki, L. Thompson, D. Cohen, J. M. Luther, Lan Gellert, A. Vaidya, J. Barletta, T. Else, T. Giordano, S. Tomlins, W. Rainey   +15 more
semanticscholar   +1 more source

Renal potassium handling in rats with subtotal nephrectomy: modeling and analysis [PDF]

, 2018
We sought to decipher the mechanisms underlying the kidney's response to changes in K+ load and intake, under physiological and pathophysiological conditions.
Edwards, Aurelie, Layton, Anita T., Vallon, Volker   +2 more
core   +1 more source

Non-genomic regulation of intermediate conductance potassium channels by aldosterone in human colonic crypt cells [PDF]

, 2003
BACKGROUND: Aldosterone has a rapid, non-genomic, inhibitory effect on macroscopic basolateral K+ conductance in the human colon, reducing its capacity for Cl− secretion.
Bowley, K.A., Hunter, M., Morton, M.J., Sandle, G.I.   +3 more
core   +2 more sources

Aldosterone induces trained immunity: the role of fatty acid synthesis.

Cardiovascular Research, 2019
AIMS Supranormal levels of aldosterone are associated with an increased cardiovascular risk in humans, and with accelerated atherosclerosis in animal models. Atherosclerosis is a low-grade inflammatory disorder, with monocyte-derived macrophages as major
Charlotte D C C van der Heijden, S. Keating, L. Groh, L. Joosten, M. Netea, N. Riksen   +5 more
semanticscholar   +1 more source

Aldosterone Predicts Cardiovascular, Renal, and Metabolic Disease in the General Community: A 4‐Year Follow‐Up

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2015
Background We recently reported that normal aldosterone levels are associated with cardiovascular, renal, and metabolic disease in a sample of the US general community (Visit 1).
Alessia Buglioni, Valentina Cannone, S. Jeson Sangaralingham, Denise M. Heublein, Christopher G. Scott, Kent R. Bailey, Richard J. Rodeheffer, Riccardo Sarzani, John C. Burnett Jr   +8 more
doaj   +1 more source

The Effects of Different Calcium Channel Blockers on Aldosterone-Producing Adenoma Cells

Frontiers in Endocrinology, 2020
Purpose: The aim of this study is to examine the effects of different kinds of calcium channel blockers (CCBs) on primary aldosterone-producing adenoma (APA) mainly with KCNJ5 mutations.
Fen Wang, Fen Wang, Xiaosen Ma, Anli Tong, Yushi Zhang, Jin Wen, Yuxiu Li   +6 more
doaj   +1 more source

Effect of Cyclooxygenase(COX)-1 and COX-2 inhibition on furosemide-induced renal responses and isoform immunolocalization in the healthy cat kidney [PDF]

, 2015
BACKGROUND: The role of cyclooxygenase(COX)-1 and COX-2 in the saluretic and renin-angiotensin responses to loop diuretics in the cat is unknown. We propose in vivo characterisation of isoform roles in a furosemide model by administering non-steroidal ...
A Hayes, B Mann, B Rose, B Rose, B Rose, CM Hao, DA Heller, DO Stichtenoth, F Catella-Lawson, F Nantel, G Giovanni, H Syme, H. Syme, J Hippisley-Cox, J Peti-Peterdi, J. Elliott, J. N. King, JA Jakobsen, K Schumacher, K. Smith, KA Kirchner, KL Therland, KN Khan, KN Khan, L Pelligand, L Pelligand, L. Pelligand, M Komhoff, M Meskell, M Sabbatini, N. Suemanotham, P. Lees, PA Friedman, RC Harris, RC Harris, RE Jepson, S Yu, V Campean, V Sreenivasan, VB Schmid, W. Seewald, WA Corsini, XR He   +42 more
core   +2 more sources

Captopril challenge test in the diagnosis of primary aldosteronism: consistency between 1- and 2- h sampling

Frontiers in Endocrinology, 2023
ObjectiveTo examine the consistency of plasma aldosterone concentration at 1 and 2 h in the captopril challenge test (CCT) and to explore the possibility of replacing 2-h aldosterone concentration with 1-h aldosterone concentration for diagnosis of ...
Xinyu Liu, Chao Guo, Jin Bian, Sufang Hao, Ying Lou, Huimin Zhang, Xianliang Zhou, Jun Cai, Wenjun Ma   +8 more
doaj   +1 more source