Pharmacokinetics of alendronate in a combined Alendronate/Vitamin D3 tablet in healthy volunteers using plasma and urine data [PDF]
Songklanakarin Journal of Science and Technology (SJST), 2013 Alendronate is indicated for treatment of a variety of bone metabolism disorders. In spite of quite low plasma concentrationsfollowing oral administration, pharmacokinetic study of alendronate based on plasma concentrations had normally been reported for
Chalitpon Na nakorn +3 more
doaj
Journal of Cachexia, Sarcopenia and Muscle, 2018 Background A global consensus on the loss of skeletal muscle mass and function in humans refers as sarcopenia and cachexia including diabetes, obesity, renal failure, and osteoporosis. Despite a current improvement of sarcopenia or cachexia with exercise
Hsien‐Chun Chiu +5 more
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JBMR Plus, 2021 Increases in bone mineral density (BMD) with osteoporosis treatment are associated with reduced fracture risk. Increasing BMD is therefore a goal of osteoporosis therapy.
Felicia Cosman +11 more
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Recent advances: rheumatology [PDF]
, 2000 No abstract ...
Madhok, R., Kerr, H., Capell, H.A.
core +4 more sources
Common osteoporosis drug associated with increased rates of depression and anxiety
Scientific Reports, 2021 Osteoporosis affects over 10 million Americans over 50. Bisphosphonate therapy, mainly alendronate, is amongst the most prescribed treatments for the disease.
Dro Keshishi +2 more
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Biomechanical Computed Tomography analysis (BCT) for clinical assessment of osteoporosis. [PDF]
, 2020 The surgeon general of the USA defines osteoporosis as "a skeletal disorder characterized by compromised bone strength, predisposing to an increased risk of fracture." Measuring bone strength, Biomechanical Computed Tomography analysis (BCT), namely ...
Bouxsein, ML +6 more
core
A fast and simple spectrofluorometric method for the determination of alendronate sodium in pharmaceuticals [PDF]
BioImpacts, 2014 Introduction: Alendronate sodium enhances bone formation and increases osteoblast proliferation and maturation and leads to the inhibition of osteoblast apoptosis.
Jafar Ezzati Nazhad Dolatabadi +3 more
doaj +1 more source
Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics
Advanced Materials, EarlyView.This review summarizes the current status of polymeric, ceramic, and metallic absorbable materials in orthopedic applications, and highlights several innovative strategies designed to enhance mechanical performance, control degradation, and promote bioactivity. We also discuss the progress and translational potential of absorbable materials in treating
Zhao Wang +13 more
wiley +1 more source
Effects of 24 months of treatment with romosozumab followed by 12 months of denosumab or placebo in postmenopausal women with low bone mineral density : a randomized, double-blind, phase 2, parallel group study [PDF]
, 2018 Over 12 months, romosozumab increased bone formation and decreased bone resorption, resulting in increased bone mineral density (BMD) in postmenopausal women with low BMD (NCT00896532).
Binkley +17 more
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JRSM, 2002 Alendronate and other bisphosphonates are effective in the prevention and treatment of osteoporosis by inhibiting bone resorption. In normal circumstances a small initial fall in serum calcium has no clinical consequences because it is corrected by an increase in parathyroid hormone (PTH) secretion1.
Richard J, Maclsaac +2 more
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