Results 41 to 50 of about 11,942 (246)

Attomolar Detection of HIV‐1 With Label‐Free RCA‐rCRISPR on Smartphone

open access: yesAdvanced Science, EarlyView.
A new diagnostic strategy integrating rolling circle amplification (RCA) with a plasmid reporter–based ratiometric CRISPR (rCRISPR) system was developed to detect unfragmented HIV genomes with single‐digit attomolar sensitivity. The method quantifies targets using the plasmid relaxation ratio and employs a smartphone‐based mini‐gel device to enable ...
Noor Mohammad   +12 more
wiley   +1 more source

Diagnóstico diferencial en alergia alimentaria [PDF]

open access: yes, 2023
Es importante establecer el diagnóstico diferencial de alergia alimentaria con otras alteraciones, por ejemplo: reacciones tóxicas que ocurren en cualquier persona expuesta a una cantidad suficiente de algún alérgeno, y reacciones no tóxicas que dependen
Liziane Nunes de Castilho Santos
core   +1 more source

Critical Roles of O‐Acetylation Revealed by Synthetic Trisaccharide Antigens for a Broad‐Spectrum Anti‐Salmonella Vaccine

open access: yesAdvanced Science, EarlyView.
A synthetic glycoconjugate vaccine based on a diacetylated Salmonella trisaccharide elicits broadly protective antibodies against four major human pathogenic serovars. Mechanistic studies identify 2,3‐di‐O‐acetylation of rhamnose as a critical determinant of antigen recognition and breadth of protection, establishing a new strategy for broad‐spectrum ...
Xingling Pan   +7 more
wiley   +1 more source

The effectiveness and safety of subcutaneous immunotherapy for inhalable allergens in patients with respiratory allergies

open access: yesRevista Alergia México, 2019
Background: Specific immunotherapy is a treatment aimed at modifying the course of the allergic disease, with which important immunological and clinical changes are achieved.
Francisco Valle-Rodríguez   +7 more
doaj   +1 more source

Associação entre alergia ocular leve e ceratocone em crianças

open access: yesRevista Brasileira de Oftalmologia, 2021
RESUMO Objetivo: Avaliar a possibilidade de alterações precoces sugestivas de ectasia detectáveis no Pentacam em casos sutis de alergia ocular em crianças.
Tatiana do Couto Morais Scaglioni   +3 more
doaj   +1 more source

RAST, Inmunoblot, Inmunocap e ISAC en alergia alimentaria [PDF]

open access: yes, 2023
Después del descubrimiento de la IgE, los avances tecnológicos han proporcionado nuevas herramientas de laboratorio para la cuantificación de anticuerpos IgE específicos de alérgenos en suero y en la superficie de basófilos-mastocitos.
Herberto J. Chong Neto
core   +1 more source

IgG Glycosylation‐Dependent CLEC7A Signaling Drives Podocyte Dysfunction in Lupus Nephritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Lupus nephritis (LN) is a severe complication of systemic lupus erythematosus (SLE) that can lead to end‐stage kidney disease and increased mortality. IgG from patients with LN displays abnormal glycosylation, contributing to podocyte injury.
Rohit Upadhyay   +3 more
wiley   +1 more source

Alergias alimentarias

open access: yesVivat Academia. Revista de Comunicación, 2006
El sistema inmunitario está formado por una compleja red estructural de células y moléculas especializadas en diferentes funciones y distribuidas por todo el organismo. La característica distintiva de este sistema es la capacidad de reconocimiento específico de fragmentos moleculares, que conlleva el establecimiento de interacciones constantes entre ...
Vicente J. Gutiérrez Coronado   +1 more
openaire   +3 more sources

Type I Interferon Drives Dysfunction of a Distinct CD8+ HLA‐DRB1+ T Cell Subset in Systemic Lupus Erythematosus

open access: yesArthritis &Rheumatology, EarlyView.
Objective Systemic lupus erythematosus (SLE) is characterized by type I interferon (IFN) signaling and adaptive immune dysregulation. We previously identified hypomethylation of HLA‐DRB1 and STAT1 in SLE CD8+ T cells, enabling aberrant IFN‐driven HLA‐DRB1 expression and expansion of a distinct CD8+ T cell subset. This study characterized CD8+ HLA‐DRB1+
Huizhong Long   +3 more
wiley   +1 more source

Urticaria crónica como reacción atípica luego de la picadura de véspidos

open access: yesRevista Alergia México
Antecedentes: La picadura de himenópteros puede producir reacciones mediadas por IgE, reacciones tóxicas o reacciones atípicas poco frecuentes. Dentro de las manifestaciones cutáneas por reacciones atípicas se incluye urticaria por frío, y sólo existe un
Patricia Andrade Garbán   +4 more
doaj   +1 more source

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