Results 101 to 110 of about 442,016 (297)

Optical Molecular Imaging of Epidermal Growth Factor Receptor Expression to Improve Detection of Oral Neoplasia

Neoplasia: An International Journal for Oncology Research, 2009
Background: The development of noninvasive molecular imaging approaches has the potential to improve management of cancer. Methods: In this study, we demonstrate the potential of noninvasive topical delivery of an epidermal growth factor-Alexa 647 (EGF ...
Nitin Nitin, Kelsey J. Rosbach, Adel El-Naggar, Michelle Williams, Ann Gillenwater, Rebecca R. Richards-Kortum   +5 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

QDs versus Alexa: reality of promising tools for immunocytochemistry

Journal of Nanobiotechnology, 2009
Background The unique photonic properties of the recently developed fluorescent semiconductor nanocrystals (QDs) have made them a potential tool in biological research. However, QDs are not yet a part of routine laboratory techniques.
Castell Onofre, Rossinyol Emma, Nogués Carme, Montón Helena, Roldán Mònica   +4 more
doaj   +1 more source

Estrategia de marketing digital para la marca personal: “Alexa shoot”.

, 2022
El siguiente trabajo aborda los principales pasos a tomar en cuenta para crear una estrategia de Marketing Digital para una marca totalmente nueva en espacio físico y virtual.
Sigarán Mata, Alexa Mercedes
core  

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Fluorometric assay for quantitation of biotin covalently attached to proteins and nucleic acids

BioTechniques, 2007
As a component of the (strept)avidin affinity system, biotin is often covalently linked to proteins or nucleic acids. We describe here a microplate-based high-throughput fluorometric assay for biotin linked to either proteins or nucleic acids based on ...
Robert H. Batchelor, Adam Sarkez, W. Gregory Cox, Iain Johnson   +3 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

4D super-resolution microscopy with conventional fluorophores and single wavelength excitation in optically thick cells and tissues.

PLoS ONE, 2011
BackgroundOptical super-resolution imaging of fluorescently stained biological samples is rapidly becoming an important tool to investigate protein distribution at the molecular scale.
David Baddeley, David Crossman, Sabrina Rossberger, Juliette E Cheyne, Johanna M Montgomery, Isuru D Jayasinghe, Christoph Cremer, Mark B Cannell, Christian Soeller   +8 more
doaj   +1 more source

From ELIZA to Alexa

, 2023
Abstract Rhee traces the history of caring Artificial intelligence (AI) technologies to explicate how these technologies replicate historic gendered and racialised dynamics associated with care labour. From its early imagining in Turing’s text, Rhee argues, AI has been entangled with care labour, forms of labour historically performed by
openaire   +1 more source

The Magazine Women Believed in: "Marriage Advice" 1950-1955 [PDF]

, 2012
In the United States society, the 1950s is seen as a time of great conservatism where both men and women were placed into specific gender roles that dictated much of how they lived their lives.
Klos, Alexa
core