Results 91 to 100 of about 622,530 (302)
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Build, Resist, Be Resilient, and Rebuild: Advising as a Womxn of Color [PDF]
, 2019 Racial battle fatigue, cultural taxation, and the challenge of practicing self-care in the midst of tumultuous racial campus climate are all powerful forces that affect how Advisors of Color show up in their relationships with college students.
Erb, Alexa R. D.
core +1 more source
FEBS Open Bio, EarlyView.We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
Reporter Assay for Endo/Lysosomal Escape of Toxin-Based Therapeutics
Toxins, 2014 Protein-based therapeutics with cytosolic targets are capable of exhibiting their therapeutic effect once they have escaped from the endosomes or lysosomes.
Roger Gilabert-Oriol +8 more
doaj +1 more source
, 2018 On Friday, April 20, 2018, Gettysburg College students organized a campus-wide walkout to protest all forms of gun violence as part of Gettysburg College’s first annual Peace and Justice Week.
Laboy, Alexa
core
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Doing Virtual Companionship with Alexa
Social InteractionTechnologists often claim that virtual assistants, e.g., smart speakers, can offer 'smart companionship for independent older people'. However, the concept of companionship manifested by such technologies is rarely explained further.
Lauren Hall, Saul Albert, Elizabeth Peel
doaj +1 more source
Application of four dyes in gene expression analyses by microarrays
BMC Genomics, 2005 Background DNA microarrays are widely used in gene expression analyses. To increase throughput and minimize costs without reducing gene expression data obtained, we investigated whether four mRNA samples can be analyzed simultaneously by applying four ...
van Schooten Frederik J +3 more
doaj +1 more source
Icts, Social Media, & the Future of Human Rights [PDF]
, 2019 As communication increasingly shifts to digital platforms, information derived from online open sources is starting to become critical in creating an evidentiary basis for international crimes.
Koenig, Alexa, Mehandru, Nikita
core +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source