Results 71 to 80 of about 622,530 (302)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Author Correction: Hippocampal oxytocin receptors are necessary for discrimination of social stimuli

open access: yesNature Communications, 2018
The original version of this Article contained an error in the spelling of the author Alexa H. Veenema, which was incorrectly given as Alexa Veenema. This has now been corrected in both the PDF and HTML versions of the Article.
Tara Raam   +4 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

GluLa-DPG-PEG600 nanopolymer binds proteins and spreads to rats’ organs and tissues

open access: yesБіологічні студії, 2016
In this article, we described the ability of GluLa-DPG-PEG600 nanopolymer based on the pseudopolyamino acids to bind proteins and its localization in rats organs and tissues after intravenous and intramuscular injections.
B. O. Chekh   +4 more
doaj   +1 more source

Alexa, M.D. [PDF]

open access: yesComputer, 2022
Sarah Jane Mee, Salam Daher
openaire   +1 more source

The Art of Processing a Collection [PDF]

open access: yes, 2015
One of the most astounding things about Special Collections and Archives is that there is no necessarily right or wrong way to process a collection.
Schreier, Alexa R.
core   +1 more source

The Roles of Membrane Rafts in CD32A-Mediated Phagocytosis [PDF]

open access: yes, 2007
Membrane rafts are highly dynamic heterogeneous sterol- and sphingolipid-rich micro-domains on cell surfaces. They are generally believed to provide residency for cell surface molecules (e.g., adhesion and signaling molecules) and scaffolding to ...
Cheng Zhu   +2 more
core   +2 more sources

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

The Vindictive Monk or The Fatal Ring [Transcript] [PDF]

open access: yes
Calini discovers he is a foundling, abandoned as an infant with a ring left among his. The story continues with Calini as an adult, returning from the home of his beloved, Alexa. Calini is suddenly taken hostage and locked in a dungeon by Sceloni, a monk.
Crookenden, Isaac
core   +1 more source

Digitally Yours; The Body in Contemporary Photography [PDF]

open access: yes, 2009
This article analyses two artworks by contemporary photographers, Alexa Wright and Wendy McMurdo. It focuses in particular on the relationship between digital technologies and representation of the body, and on the changes to accepted paradigms of ...
Rubinstein, Daniel
core  

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