Results 81 to 90 of about 442,016 (297)

Analisis SWOT Pengembangan Bisnis Alexa Bakery Banjarmasin [PDF]

, 2023
Penelitian ini bertolak dari salah satu upaya yang dapat dilakukan oleh pelaku usaha dalam pengembangan usahanya adalah dengan melakukan analisis SWOT, analisis ini dapat dijadikan sebagai landasan pelaku usaha agar dapat mencapai target usahanya ...
Mulyana, Nova
core   +1 more source

Application of four dyes in gene expression analyses by microarrays

BMC Genomics, 2005
Background DNA microarrays are widely used in gene expression analyses. To increase throughput and minimize costs without reducing gene expression data obtained, we investigated whether four mRNA samples can be analyzed simultaneously by applying four ...
van Schooten Frederik J, van Herwijnen Marcel HM, Staal Yvonne CM, van Delft Joost HM   +3 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

GluLa-DPG-PEG600 nanopolymer binds proteins and spreads to rats’ organs and tissues

Біологічні студії, 2016
In this article, we described the ability of GluLa-DPG-PEG600 nanopolymer based on the pseudopolyamino acids to bind proteins and its localization in rats organs and tissues after intravenous and intramuscular injections.
B. O. Chekh, M. V. Ferens, Y. V. Martyn, D. D. Ostapiv, V. V. Vlizlo   +4 more
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Panther Pride: Homecoming 2017 Oral History Project Recording with Alexa Devore, 06 October 2017

, 2017
Alexa Devore is a current UNI student who is involved in a wide range of activites on campus, such as the University Honors Program and Connecting Alumni to Students (CATS).
Devore, Alexa
core   +1 more source

Dynamine alexae

, 2017
alexae. Dynamine alexae Peñalver & Grimaldi, 2006 Nymphalidae: Biblidinae. Dominican Republic, Cordillera Septentrional between Santago and Puerto Plata, Dominican Amber; Aquitanian, early Miocene. Depository: AMNH (holotype, DR-18-2). Published figures: Peñalver & Grimaldi (2006: Figs 3–5).
openaire   +2 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Tune In, Turn On, Create!

, 2011
A completed grammar test with corrections. Part of the teaching materials used by Alexa West at the Intermountain School.
West, Alexa; Intermountain School
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source