Results 31 to 40 of about 774,994 (289)

Pitfalls associated with the use of molecular diagnostic panels in the diagnosis of cryptococcal meningitis [PDF]

open access: yes, 2017
We report the case of a kidney transplantation patient on chronic immunosuppressive therapy presenting with subacute meningitis. The final diagnosis of cryptococcal meningitis was delayed due to 2 false-negative cryptococcal results on a molecular ...
Burnham, Carey-Ann   +5 more
core   +2 more sources

Passaging of a Newcastle disease virus pigeon variant in chickens results in selection of viruses with mutations in the polymerase complex enhancing virus replication and virulence [PDF]

open access: yes, 2010
Some Newcastle disease virus (NDV) variants isolated from pigeons (pigeon paramyxovirus type 1; PPMV-1) do not show their full virulence potential for domestic chickens but may become virulent upon spread in these animals.
Dortmans, J.C.F.M.   +3 more
core   +2 more sources

Alexander Disease☆

open access: yes, 2017
Alexander disease is a leukodystrophy caused by dominant missense mutations in the gene encoding the glial fibrillary acidic protein. Individuals with this disorder often present with a typical neuroradiologic pattern including white matter abnormalities with brainstem involvement, selective contrast enhancement, and structural changes to the basal
M. Brenner, B.R. Barton
  +5 more sources

Targeting inflammation to reduce cardiovascular disease risk [PDF]

open access: yes, 2017
This joint themed section of the British Journal of Pharmacology and the British Journal of Clinical Pharmacology stems from a joint British Pharmacological Society – Italian Society of Pharmacology symposium held at the 37th National Congress of the ...
Cirino, Guiseppe, Maffia, Pasquale
core   +1 more source

Juvenile Alexander Disease: a Case Report

open access: yesEurasian Journal of Medicine, 2019
Alexander disease is a rare autosomal recessive disorder that is characterized by degeneration of the white matter in the central nervous system. Alexander disease is a leukodystrophy that is usually observed in early childhood but rarely in adults.
Halit Ozkaya   +6 more
doaj   +1 more source

Monocytes Elicit a Neutrophil-Independent Th1/Th17 Response Upon Immunization With a Mincle-Dependent Glycolipid Adjuvant

open access: yesFrontiers in Immunology, 2022
Successful subunit vaccination with recombinant proteins requires adjuvants. The glycolipid trehalose-dibehenate (TDB), a synthetic analog of the mycobacterial cord factor, potently induces Th1 and Th17 immune responses and is a candidate adjuvant for ...
Christiane Desel   +9 more
doaj   +1 more source

Creutzfeldt-Jakob disease and homocysteine levels in plasma and cerebrospinal fluid [PDF]

open access: yes, 2005
Background: There is evidence that homocysteine contributes to various neurodegenerative disorders. Objective: To assess the values of homocysteine in patients with Creutzfeldt-Jakob disease (CJD) in both cerebrospinal fluid (CSF) and plasma.
Bottiglieri T   +11 more
core   +1 more source

Slow gait speed and cardiac rehabilitation participation in older adults after acute myocardial infarction [PDF]

open access: yes, 2018
Background Lack of participation in cardiac rehabilitation ( CR ) and slow gait speed have both been associated with poor long‐term outcomes in older adults after acute myocardial ...
Alexander, Karen P   +5 more
core   +2 more sources

The Accident and its Causes: Pseudo-Alexander on Aristotle (Metaphysics E 3) [PDF]

open access: yes, 2018
Pseudo-Alexander\u2019s commentary in Metaphysics \u395 3 is one of the three ancient commentaries which came down to us together with Ascepius\u2019s commentary and Pseudo-Philoponus\u2019s one, in Latin.
Salis, Rita
core   +1 more source

Molecular Diagnosis of Alexander Disease

open access: yesPediatric Neurology Briefs, 2002
The value of clinical and MRI criteria in the diagnosis of Alexander disease was determined by using GFAP gene sequencing as the confirmatory assay in 13 patients with variable ages of onset in a study at Children’s National Medical Center, Washington ...
J Gordon Millichap
doaj   +1 more source

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