Results 41 to 50 of about 306,111 (180)
An Unusual Presentation of Juvenile Alexander Disease
, 2011 Alexander disease is a rare leukodystrophy that most often presents in infancy but also includes neonatal, juvenile, and adult variants. Juvenile Alexander disease presents primarily with bulbar symptoms between 2 and 12 years of age.
Maria Joana Osorio +2 more
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Focal Central White Matter Lesions in Alexander Disease
, 2011 Alexander disease is a neurodegenerative disorder of the central white matter caused by dominant mutations in GFAP, the gene encoding glial fibrillary acidic protein. Magnetic resonance imaging pattern recognition studies have established characteristic
Prust, MJ +10 more
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Olfactory Bulb Hyperplasia in Genetically Confirmed Infantile Alexander Disease [PDF]
Journal of Clinical and Diagnostic Research, 2019 Alexander Disease (AxD) is a well-known leukodystrophy with characteristic findings on brain Magnetic Resonance Imaging (MRI) including bilaterally symmetric, frontal confluent white matter signal abnormality with relative sparing of the parietal and ...
Michael Todd Jurkiewicz +3 more
doaj +1 more source
Advanced Science, 2023 Creating a cellular model of Alzheimer's disease (AD) that accurately recapitulates disease pathology has been a longstanding challenge. Recent studies showed that human AD neural cells, integrated into three‐dimensional (3D) hydrogel matrix, display key
Matthias Hebisch +6 more
doaj +1 more source
Reviews in Cardiovascular Medicine, 2022 Background: It is clinically widely overlooked that many patients with Marfan- (MFS) or Loeys-Dietz-Syndrome (LDS) are obese. While anthropometric routine parameters are not very suitable, the modern Bioelectrical Impedance Analysis (BIA) seems superior ...
Sebastian Freilinger +12 more
doaj +1 more source
Vigabatrin-Associated “Acute Encephalopathy”
Pediatric Neurology Briefs, 2000 A 6-month-old girl with Alexander disease and hydrocephalus, treated at Children’s Hospital, Tubingen, Germany, developed acute encephalopathy within 3 days of starting vigabatrin (VGB).
J Gordon Millichap
doaj +1 more source
Infantile Alexander Disease: Case Report and Review of Literature [PDF]
Journal of Clinical and Diagnostic Research, 2017 Alexander Disease (AD) is an autosomal dominant leukodystrophy and occurs predominantly in infants and children. It usually results in death within ten years after onset. Among the four subtypes, infantile form comprises the most of affected individuals.
Soumyabrata Sarkar +4 more
doaj +1 more source
Infantile Alexander disease with late onset infantile spasms and hypsarrhythmia
Balkan Journal of Medical Genetics, 2019 Alexander disease (AxD) is a rare autosomal dominant leukodystrophy with three clinical subtypes: infantile, juvenile and adult. Forms differ by age of symptoms occurrence and the clinical presentation.
Paprocka J +4 more
doaj +1 more source
Geospatial Health, 2010 Spatial autocorrelation is problematic for classical hierarchical cluster detection tests commonly used in multidrug resistant tuberculosis (MDR-TB) analyses as considerable random error can occur.
Benjamin G. Jacob +5 more
doaj +1 more source