Results 1 to 10 of about 2,811 (168)

Effectiveness of treatments to prevent femoral periprosthetic bone loss following total hip arthroplasty: a network meta-analysis [PDF]

Frontiers in Pharmacology
BackgroundThe objective of this study was to conduct a systematic review and network meta-analysis (NMA) to compare the efficacy of various anti-osteoporosis drugs in preventing femoral periprosthetic bone loss following total hip arthroplasty (THA ...
Zhi-Hu Zhao, Tao Ling, Songqing Ye, Wei Luo, Jian-Xiong Ma, Xinlong Ma   +5 more
doaj   +2 more sources

A New Look at the Most Successful Prodrugs for Active Vitamin D (D Hormone): Alfacalcidol and Doxercalciferol

Molecules, 2009
Alfacalcidol (1α-hydroxyvitamin D3) has been widely used since 1981 as a prodrug for calcitriol (1α,25-dihydroxyvitamin D3) in the treatment of hypocalcemia, chronic renal failure, hypoparathyroidism and osteoporosis.
Noboru Kubodera
exaly   +3 more sources

Korelasi Kekuatan Otot Menggenggam dengan Otot Levator Ani pada Penderita Prolapsus Organ Panggul

Obgynia, 2023
Tujuan: Penelitian ini bertujuan mengetahui perbedaan kekuatan otot levator ani dan otot menggenggam sebelum dan sesudah pemberian analog vitamin D3 (alfacalcidol) dan mengetahui korelasi antara kekuatan kontraksi otot levator ani dan kekuatan kontraksi ...
Lulu Nurul Ula, Jusuf Sulaeman Effendi, R.M. Sonny Sasotya   +2 more
doaj   +1 more source

Comparative effect of eldecalcitol and alfacalcidol on bone microstructure: A preliminary report of secondary analysis of a prospective trial

Osteoporosis and Sarcopenia, 2021
Objectives: To compare the effect of eldecalcitol and alfacalcidol on skeletal microstructure by high-resolution peripheral QCT (HR-pQCT). Methods: This was a substudy of a randomized, double-blind, active comparator trial.
Xiaolin Ni, Juan Feng, Yan Jiang, Li Zhang, Wei Yu, Ou Wang, Mei Li, Xiaoping Xing, Toshio Matsumoto, Weibo Xia   +9 more
doaj   +1 more source

Effects of alfacalcidol on cardiovascular outcomes according to alkaline phosphatase levels in the J-DAVID trial

Scientific Reports, 2022
In the Japan Dialysis Active Vitamin D (J-DAVID) trial, oral alfacalcidol numerically, but not significantly, increased the risk of cardiovascular events among patients undergoing hemodialysis.
Tatsufumi Oka, Yusuke Sakaguchi, Yoshitaka Isaka, Haruka Ishii, Daijiro Kabata, Ayumi Shintani, Shinya Nakatani, Tomoaki Morioka, Katsuhito Mori, Masaaki Inaba, Masanori Emoto, Tetsuo Shoji   +11 more
doaj   +1 more source

Alfacalcidol modulates oxidative stress parameters in the peripheral blood of patients with active rheumatoid arthritis [PDF]

Journal of the Serbian Chemical Society, 2016
Hormone D and its analogues display immunomodulatory activities providing a beneficial effect in immunoinflammatory diseases. The aim of this study was to assess the effect of alfacalcidol treatment on superoxide dismutase (SOD), catalase (CAT) and ...
Živanović-Radnić Tatjana, Simić-Pašalić Katarina, Šefik-Bukilica Mirjana, Misirlić-Denčić Sonja, Isaković Anđelka M., Stojković Tihomir, Petronijević Nataša, Damjanov Nemanja, Vojinović Jelena   +8 more
doaj   +1 more source

Effect of alfacalcidol on bone regeneration in senile rats

Bolʹ, Sustavy, Pozvonočnik, 2022
Background. Among the drugs that have a pleiotropic effect on bone, attention is drawn to alfacalcidol – the precursor of the active form of D-hormone.
F.V. Klymovytskyy, V.G. Klymovytskyy, N.V. Dedukh   +2 more
doaj   +1 more source

Comparison of Paricalcitol (I.V) and Alfacalcidol (I.V) in Treatment of Secondary Hyperparathyroidism (SHPT) in Hemodialysis Patients

Journal of Rawalpindi Medical College, 2020
Objective of study: To Compare the efficacy of Alfacalcidol (I.V) and Paricalcitol (I.V) for the treatment of secondary hyperparathyroidism  (SHPT)  in hemodialysis patients.
Mansoor Abbas Qaisar, Zain ul Abideen, Fateh Sher Chattah, Muhammad Nadeem, Zahid Hafeez   +4 more
doaj   +1 more source

Comparison between paricalcitol versus cinacalcet therapy in the management of secondary hyperparathyroidism among prevalent hemodialysis patients [PDF]

Journal of Nephropharmacology, 2022
Introduction: Secondary hyperparathyroidism (SHPT) is one of the components of chronic kidney disease–mineral bone disorder (CKD-MBD) with significant contribution to the morbidity and mortality among prevalent hemodialysis (HD) patients.
Maha A. Behairy, Osama Mahmoud, Ayman Rabie Ibrahim, Aber H. Baki   +3 more
doaj   +1 more source

Quantification of Alfacalcidol Tablets Dissolution Content by Chemical Derivatization and LC-MS

Journal of Analytical Methods in Chemistry, 2020
Application of liquid chromatography-mass spectrometry (LC-MS) in analyzing the content of alfacalcidol tablets dissolution faces big challenges due to the low amount of alfacalcidol in each tablet and the low ionization efficacy of the compound with ...
Yang Liu, Xi Chen, Song Yuan, Wanhui Liu, Lan He, Qingsheng Zhang   +5 more
doaj   +1 more source