Results 41 to 50 of about 3,569 (208)

Cholecalciferol vs. Small Doses of Alfacalcidol vs. Placebo in Chronic Kidney Disease Patients on Hemodialysis: A Randomized Parallel Group Study

open access: yesFrontiers in Medicine, 2022
BackgroundThe ability of extrarenal tissues to convert 25(OH)D (calcidiol) into 1,25(OH)2D (calcitriol) and dependence of the conversion on substrate levels provide the rationale for supplementing vitamin D in dialysis patients who usually have severe ...
Joanna Matuszkiewicz-Rowińska   +7 more
doaj   +1 more source

Roles of active forms of vitamin D in supporting innate immune systems and in reducing excess inflammation in COVID-19

open access: yesТерапевтический архив, 2021
A reduced supply of micronutrient vitamin D leads to a more severe course of coronavirus infection (COVID-19). Vitamin D deficiency is combined with a decrease in innate antiviral immunity and excess of inflammation.
Olga A. Gromova   +4 more
doaj   +1 more source

Daily calcium profile in diagnosis of hypo- and hypercalcemia in patients with chronic hypoparathyroidism. clinical case series

open access: yesОжирение и метаболизм, 2021
Hypoparathyroidism is a rare endocrine disorder characterized by hypocalcemia and hyperphosphatemia, due to absent or inappropriately low serum parathyroid hormone (PTH) levels.
E. V. Kovaleva   +2 more
doaj   +1 more source

A rare case of acute kidney injury and anemia induced by hypercalcemia

open access: yesClinics and Practice, 2019
Hypercalcemia may result in acute kidney injury (AKI) and arterial hypertension. Anemia as a consequence of this constellation is nowhere described.
Suparpit von Bormann   +2 more
doaj   +1 more source

Parameters of Vitamin D Metabolism in Patients with Hypoparathyroidism

open access: yesMetabolites, 2022
Only a few studies evaluating the metabolism of vitamin D in patients with hypoparathyroidism (HypoPT) have been performed thus far, and, in particular, they mainly investigated the process of vitamin D activation (specifically, 1α-hydroxylation).
Artem Zhukov   +10 more
doaj   +1 more source

Otsenka riska padeniy zhenshchin s postmenopauzal'nymosteoporozom, poluchayushchikh al'fakal'tsidol

open access: yesОстеопороз и остеопатии, 2010
The study objective: to assess the influence of alfacalcidol treatment on risk of falling in real clinical practice. Methods. Prospective cohort study included 46 postmenopausal women aged from 52 to 78, who had high risk of falling, low bone mineral ...
M. V. Strunina   +3 more
doaj   +1 more source

Vitamin D: Physiology, Pharmacology and Clinical Evidence for Supplementation—A Narrative Review

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 5, November 2026.
ABSTRACT Vitamin D is a nutrient and prohormone obtained from diet and supplements and synthesized in the skin. It is essential for calcium and phosphate homeostasis and skeletal health and influences multiple extra‐skeletal processes, yet deficiency remains common worldwide.
Jyrki K. Virtanen
wiley   +1 more source

The efficacy of combined treatment of secondary hyperthyroidism in pre-dialysis chronic kidney disease patients

open access: yesBolʹ, Sustavy, Pozvonočnik, 2023
Background. It is well known that chronic kidney di­sease (CKD) patients develop mineral and bone disturbances which lead to the development of renal osteodystrophy and its complications.
L.P. Martynyuk   +2 more
doaj   +1 more source

Exploring Vitamin D Metabolism in Gynaecological Malignancies: Redox‐Dependent and Redox‐Independent Anticancer Mechanisms From Preclinical Models to Clinical Evidence

open access: yesCancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Gynaecological malignancies account for over 1.4 million new diagnoses, with outcomes constrained by late‐stage presentation and chemoresistance. Dysregulated redox homeostasis is a hallmark of tumourigenesis. Tumour cells maintain elevated basal reactive oxygen species (ROS), which support proliferative signalling but may also increase ...
Hoi Ching Cherry Chan   +4 more
wiley   +1 more source

EFFECTS OF ALFACALCIDOL ON THE CONTRACTILE PROPERTIES OF THE GASTROCNEMIUS MEDIALIS MUSCLE IN ADULT AND OLD RATS [PDF]

open access: yes, 2011
Vitamin D deficiency is associated with muscle weakness. It is unknown, however, how supra-physiological levels of vitamin D affect skeletal muscle.
Rittweger, Jörn   +5 more
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