Results 51 to 60 of about 3,471 (204)

EFFECTS OF ALFACALCIDOL ON THE CONTRACTILE PROPERTIES OF THE GASTROCNEMIUS MEDIALIS MUSCLE IN ADULT AND OLD RATS [PDF]

, 2011
Vitamin D deficiency is associated with muscle weakness. It is unknown, however, how supra-physiological levels of vitamin D affect skeletal muscle.
Rittweger, Jörn, de Haan, Arnold, A, Shiraishi, Degens, Hans, Testerink, Janwillem, Richard T, Jaspers   +5 more
core  

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, Volume 30, Issue 3, Page 309-322, June 2026.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

FGF23 and Immune Cell Signatures Causally Linked to Subarachnoid Hemorrhage: Evidence From Multi‐Omics and Genetic Colocalization

Brain and Behavior, Volume 16, Issue 5, May 2026.
Causal links identified between five inflammatory proteins, 22 immune cell types, and subarachnoid hemorrhage (SAH) via Mendelian randomization. Multi‐omics integration (pQTL, eQTL) revealed regulatory mechanisms underlying inflammation in SAH. FGF23 and CD4 Tregs emerged as key therapeutic targets, supported by colocalization and replication analysis.
Xingjie Shi, Cheng Zhang, Tao Yang, Zhiming Sun, Chao Wang, Lucheng Zhou, Shiqiang Hou, Ning Lin, Lanlan Zhang   +8 more
wiley   +1 more source

Common Gynecologic Issues in Patients Post‐Kidney Transplantation

Clinical Transplantation, Volume 40, Issue 5, May 2026.
ABSTRACT Advances in kidney transplantation have transformed survival and quality of life for women with end‐stage renal disease, necessitating a focus on long‐term health care for this population. Female kidney transplant recipients (KTR) experience a unique spectrum of gynecologic issues shaped by persistent hormonal dysregulation, lifelong ...
Mary Elaine Graham, Janelle Moulder, Eva Reina, Oona O'Neill, Emily McCracken   +4 more
wiley   +1 more source

Endocrinologist‐Led Management of Endocrine Immune‐Related Adverse Events: Real‐World Evidence Supporting the Japan Endocrine Society Guidelines

Cancer Medicine, Volume 15, Issue 4, April 2026.
During the study period, 709 patients were treated with immune checkpoint inhibitors (ICIs) at our institution. Endocrine immune‐related adverse events (irAEs) were diagnosed in 84 patients, all of whom were evaluated and managed by endocrinologists; the most common irAEs were thyroid dysfunction (64.3%) and adrenal insufficiency (42.9%), followed by ...
Kota Nishihama, Hajime Fujimoto, Kanako Saito, Chisa Inoue, Yuko Okano, Atsuro Takeshita, Mei Uemura, Corina N. D'Alessandro‐Gabazza, Esteban C. Gabazza, Yutaka Yano, Taro Yasuma   +10 more
wiley   +1 more source

Burosumab in Unidentifiable Tumor‐Induced Osteomalacia

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Tumor‐induced osteomalacia (TIO) can be challenging due to underlying tumors being either unresectable or unidentifiable. Burosumab, an anti‐FGF23 monoclonal antibody, has been proven to be effective in treating TIO but is currently not subsidized for this indication in Australia.
Yi Shan Der, Santosh Chaubey, Anna Mclean, Yasmin Trinh, Shelley Pember, Ashim Sinha   +5 more
wiley   +1 more source

Prophylactic Use of Alfacalcidol in Corticosteroid-Induced Osteoporosis

, 1999
peer reviewedOne hundred and forty-five patients suffering from diseases requiring long-term treatment with high doses of corticosteroids (30 mg/day or greater of prednisolone) were recruited to the study. Patients had to be steroid naive on entry to the
Menkes, C. J., Guillevin, L., Nielsen, K., Verdickt, W., Franssen, Marcelle, Kuntz, D., Reginster, Jean-Yves   +6 more
core   +1 more source

Dialysate calcium, alfacalcidol, and clinical outcomes: A post-hoc analysis of the J-DAVID trial.

PLoS ONE, 2022
The selection of dialysate calcium concentration (D-Ca) is still controversial among chronic hemodialysis (HD) regimens. We examined the trajectories of CKD MBD parameters among the J-DAVID trial participants to see the effect of D-Ca and alfacalcidol ...
Kunitoshi Iseki, Daijiro Kabata, Tetsuo Shoji, Masaaki Inaba, Masanori Emoto, Katsuhito Mori, Tomoaki Morioka, Shinya Nakatani, Ayumi Shintani   +8 more
doaj   +1 more source

Denys‐Drash Syndrome by WT1 Gene: Clinical Variability and Management Challenges in Two Saudi Infants

Case Reports in Endocrinology, Volume 2026, Issue 1, 2026.
Background Denys‐Drash syndrome (DDS) is a rare genetic disorder characterized by mutations in the Wilms tumor suppressor gene (WT1), leading to a triad of conditions including nephrotic syndrome progressing to end‐stage renal disease (ESRD), Wilms tumor, and ambiguous genitalia.
Waleed AL-Amoudi, Raghad Alhuthil, Abdulrahman Alnwiji, Megren S. Alqarni, Sarah Murad, Afaf Alsagheir, Kalyani Sen   +6 more
wiley   +1 more source

ДВУЕДИНАЯ ВРАЧЕБНАЯ ТАКТИКА ПРЕДУПРЕЖДЕНИЯ НИЗКОЭНЕРГЕТИЧЕСКИХ ПЕРЕЛОМОВ У ЛИЦ ПОЖИЛОГО ВОЗРАСТА — ЛЕЧЕНИЕ ОСТЕОПОРОЗА И ПРОФИЛАКТИКА ПАДЕНИЙ

Архивъ внутренней медицины, 2014
Until recently low-energy fractures in the elderly associated primarily with osteoporosis, not paying enough attention to the prevention of falls. The rationale for the use of combination therapy consisting of treatment of osteoporosis (bisphosphonates ...
С. П. Филоненко, С. С. Якушин   +1 more
doaj   +1 more source