Results 61 to 70 of about 3,471 (204)

Nutraceuticals for Preventing and Managing Cancer Chemotherapy–Induced Cardiotoxicity: An Updated Comprehensive Review

Cardiology Research and Practice, Volume 2026, Issue 1, 2026.
Chemotherapy‐induced cardiotoxicity remains a major barrier to durable cancer control and survivor well‐being, arising from oxidative stress, mitochondrial injury, inflammation, and emerging pyroptotic pathways. This updated narrative review integrates mechanistic and clinical data on nutraceuticals, including amino acids, fatty acids, vitamins ...
Seyedeh-Tarlan Mirzohreh, Samad Ghaffari, Naimeh Mesri Alamdari, Erfan Banisefid, Melika Ghaffari, Arvin Namazi Shabestari, Armin Imanzadeh Ghazijahani, Neda Roshanravan, Faezeh Tarighat, Satabdi Datta Choudhury   +9 more
wiley   +1 more source

Beyond Nutritional Deficiency: Persistent Rickets as a Manifestation of Vitamin D‐Dependent Rickets Type II in a Toddler

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Vitamin D‐dependent rickets type II (VDDR‐II) is a rare hereditary disorder caused by mutations in the vitamin D receptor gene, resulting in resistance to active vitamin D and impaired calcium absorption. We report a 2‐year and 6‐month‐old female toddler presenting with persistent rickets, delayed motor milestones, dental abnormalities, and ...
Abhisek Jha, Anil Yadav, Uma Shankar Jha, Preethuja Shah, Rohan Kumar Shah, Kuldeep Timilsina, Prabha Jha, Aabish Dahal, Saugat Bagale   +8 more
wiley   +1 more source

Routine laboratory testing in hemodialysis: how frequently is it needed?

BMC Nephrology, 2022
Background: Hemodialysis patients are followed by routine laboratory testing. There is uncertainty whether these tests always lead to a change in decision-making.
Claudia Chidiac, Dania Chelala, Dany Nassar, Chadia Beaini, Hiba Azar, Serge Finianos, Celine Boueri, Jenny Hawi, Ibrahim Abdo, Mabel Aoun   +9 more
doaj   +1 more source

Repurposing Acebutolol for Osteoporosis Treatment: Insights From Multi‐Omics and Multi‐Modal Data Analysis

Clinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1463-1476, December 2025.
Overview of a multi‐omics based drug repurposing strategy. The systematic drug repurposing strategy included the following steps: (1) osteoporosis driver signaling networks were identified from multi‐omics data; (2) drug functional modules were obtained using a network fusion approach to integrate drug similarity information; (3) all drugs were ranked ...
Dan‐Yang Liu, Hui Shen, Jonathan Greenbaum, Qiao‐Rong Yi, Shuang Liang, Yue Zhang, Jia‐Chen Liu, Chuan Qiu, Lan‐Juan Zhao, Qing Tian, Kuan‐Jui Su, Zhe Luo, Li Wu, Xiang‐He Meng, Hong‐Mei Xiao, Yun Deng, Yang Li, Dragana Lovre, Vivian Fonseca, Fernando L. Sanchez, Li‐Jun Tan, Hong‐Wen Deng   +21 more
wiley   +1 more source

Alfacalcidol improves the growth velocity in children with vitamin D deficiency/insufficiency: A single center retrospective cohort study.

PLoS ONE, 2021
ObjectivesTo investigate the growth velocity-improving effects of vitamin D replacement therapy in pediatric patients diagnosed with vitamin D deficiency and insufficiency.Study designA retrospective cohort study was conducted in 34 pediatric patients ...
Satoshi Miyagaki, Mihoko Yamaguchi, Takeshi Ota, Yasuhiro Kawabe, Hidechika Morimoto, Yoshinobu Oka, Jun Mori   +6 more
doaj   +1 more source

Efficacy of Alfacalcidol Versus Calcitriol in Managing Secondary Hyperparathyroidism in Patients With Chronic Kidney Disease. [PDF]

Hosp Pharm
Background: Data comparing the efficacy of alfacalcidol to that of calcitriol in managing secondary hyperparathyroidism in patients with chronic kidney disease (CKD) is scarce.
El Nekidy WS, Ghazal I, Mallat J, Abidi E, Malik A, Madhyastha R, Hijazi F, Ghosn M.   +7 more
europepmc   +2 more sources

Increased Risk of Postoperative Complications in Elderly Hip Fracture Patients With Cognitive Impairment: Evidence From a Japanese Nationwide Database

Geriatrics &Gerontology International, Volume 25, Issue 12, Page 1930-1939, December 2025.
ABSTRACT Background Hip fractures are a major cause of morbidity and mortality in the elderly. Cognitive impairment is known to be associated with poor postoperative outcomes, but its specific impact on complications following hip fracture surgery remains under‐investigated in Japan. Methods This nationwide retrospective cohort study used the Diagnosis
Yu Mori, Kunio Tarasawa, Hidetatsu Tanaka, Naoko Mori, Kiyohide Fushimi, Toshimi Aizawa, Kenji Fujimori   +6 more
wiley   +1 more source

Treatment of established osteoporosis: a systematic review and cost–utility analysis [PDF]

, 2002
Background and aims Osteoporosis is a systemic skeletal disease, characterised by low bone mass and microarchitectural deterioration of bone tissue with a subsequent increase in bone fragility and susceptibility to fracture.
J. E. Brazier, Stevenson, M., N.W. Calvert, J.A. Kanis, Kanis, JA, Stevenson, M, Calvert, N.W., Calvert, NW, M. Lloyd Jones, Brazier, JE, Lloyd Jones, M, Kanis, J.A., M. Stevenson, Brazier, J.E., Lloyd Jones, M., Calvert, N.   +15 more
core   +1 more source

Recurrent Priapism After Living Donor Kidney Transplantation Requiring Bilateral T‐Shunt Procedure: A Case Report

IJU Case Reports, Volume 8, Issue 6, Page 567-570, November 2025.
ABSTRACT Introduction Priapism is a persistent penile erection lasting > 4 h without sexual stimulation. Ischemic priapism requires urgent management. We report a recurrent ischemic priapism case post‐living‐donor kidney transplantation necessitating multiple interventions, including bilateral T‐shunt procedures.
Hiroto Kishino, Toru Sugihara, Takuya Iwaki, Sho Nishida, Kyoko Minamisono, Takehiro Oyama, Satoshi Ando, Kimihiko Moriya, Daiki Iwami, Tetsuya Fujimura   +9 more
wiley   +1 more source

A Case of Neonatal Myositis Ossificans Related to Chronic Kidney Disease and Vitamin D Deficiency

Nephrology, Volume 30, Issue 11, November 2025.
ABSTRACT Myositis ossificans (MO) is currently defined as a self‐limiting ossifying lesion affecting any extra‐skeletal soft tissue type but mostly afflicting skeletal muscles. The pathogenetic mechanism of the disease is incompletely understood, especially in paediatric cases, and has been rarely described in neonates.
Dimitra Gialamprinou, Georgios Mitsiakos, Nikolaos Gkiourtzis, Despoina Tramma, Elisavet Diamanti   +4 more
wiley   +1 more source