Results 21 to 30 of about 3,273 (206)

Long-Term Sequential Therapy for Pregnancy- and Lactation-Associated Osteoporosis With Multiple Vertebral Fractures: A Case Report of Over 5 Years. [PDF]

Case Rep Obstet Gynecol
Background Pregnancy‐ and lactation‐associated osteoporosis (PLO) is a rare condition that may cause multiple vertebral fractures during late pregnancy or the postpartum period. Evidence regarding treatment strategies remains limited, particularly regarding long‐term outcomes of sequential regimens combining anabolic and antiresorptive therapies.
Tsuchimochi K, Tsuchimochi H.
europepmc   +2 more sources

Intermittent Oral Versus Intravenous Alfacalcidol in Dialysis Patients

Saudi Journal of Kidney Diseases and Transplantation, 2000
Patients with end-stage renal failure (ESRF) on maintenance dialysis, commonly develop secondary hyperparathyroidism and renal osteodystrophy (ROD). Alfacalcidol, taken orally or administered intravenously, is known to reverse these complications.
Mitwalli Ahmed, Alam Awatif
doaj   +1 more source

Phosphate, Fractures, and Frustration-A Missed Diagnosis of Oncogenic Osteomalacia Leading to Multisystem Complication. [PDF]

Clin Case Rep
ABSTRACT Persistent hypophosphatemia must prompt thorough evaluation. This case highlights the severe, multisystem consequences of delayed recognition of oncogenic osteomalacia. Early biochemical assessment, imaging, and multidisciplinary involvement are critical to avoid misdiagnosis and prevent irreversible complications such as skeletal fragility ...
Wilson RM, Sturridge L.
europepmc   +2 more sources

A Case of Neonatal Myositis Ossificans Related to Chronic Kidney Disease and Vitamin D Deficiency. [PDF]

Nephrology (Carlton)
ABSTRACT Myositis ossificans (MO) is currently defined as a self‐limiting ossifying lesion affecting any extra‐skeletal soft tissue type but mostly afflicting skeletal muscles. The pathogenetic mechanism of the disease is incompletely understood, especially in paediatric cases, and has been rarely described in neonates.
Gialamprinou D, Mitsiakos G, Gkiourtzis N, Tramma D, Diamanti E.   +4 more
europepmc   +2 more sources

THE POSSIBLE PROTECTIVE EFFECT OF ALFACALCIDOL ON CISPLATIN INDUCED NEPHROTOXICITY IN ADULT MALE ALBINO RATS. A HISTOLOGICAL AND IMMUNOHISTOCHEMICAL STUDY

The Egyptian Journal of Histology, 2023
:Background: Cisplatin is an antineoplastic drug for a variety of solid-organ tumors. However, its clinical applications are restricted due to its nephrotoxicity.
Ola Abd elsamie Mohamed Khalil, Alia Ismail awad, Abdelghany Hassan Abdelghany, Mohamed Gamal Ayoub   +3 more
doaj   +1 more source

Changes in treatment needs for chronic postoperative hypoparathyroidism during initiation of conventional treatment compared to stable phase of treatment

Endocrinology, Diabetes & Metabolism, 2021
Introduction In our clinical experience, need for doses of active vitamin D and calcium supplements changes during the period following a diagnosis of postsurgical hypoparathyroidism (HypoPT), but only sparse data are available.
Pernille Storm, Line Underbjerg, Lars Rejnmark   +2 more
doaj   +1 more source

Repurposing Acebutolol for Osteoporosis Treatment: Insights From Multi-Omics and Multi-Modal Data Analysis. [PDF]

Clin Pharmacol Ther
Overview of a multi‐omics based drug repurposing strategy. The systematic drug repurposing strategy included the following steps: (1) osteoporosis driver signaling networks were identified from multi‐omics data; (2) drug functional modules were obtained using a network fusion approach to integrate drug similarity information; (3) all drugs were ranked ...
Liu DY, Shen H, Greenbaum J, Yi QR, Liang S, Zhang Y, Liu JC, Qiu C, Zhao LJ, Tian Q, Su KJ, Luo Z, Wu L, Meng XH, Xiao HM, Deng Y, Li Y, Lovre D, Fonseca V, Sanchez FL, Tan LJ, Deng HW.   +21 more
europepmc   +2 more sources

Effects of alfacalcidol on circulating cytokines and growth factors in rat skeletal muscle [PDF]

, 2011
Supra-physiological levels of vitamin D induce skeletal muscle atrophy, which may be particularly detrimental in already sarcopaenic elderly. Neither the cause nor whether the atrophy is fibre type specific are known.
Jaspers, R.T., Rittweger, Jörn, Janwillem Testerink, Richard T. Jaspers, Hans Degens, Testerink, J., Degens, Hans, Jörn Rittweger, Degens, H., de Haan, A., de Haan, Arnold, Jaspers, Richard, Haan, A. de, Testerink, Janwillem, Arnold de Haan, Rittweger, J.   +15 more
core   +1 more source

Preoperative calcium and vitamin D supplementation may reduce postoperative hypocalcaemia after total thyroidectomy

Archives of Medical Science, 2021
Introduction Hypocalcaemia is the most common postoperative complication after total thyroidectomy. The purpose of the study was to evaluate the clinical usefulness of routine preoperative oral calcium and vitamin D supplementation in the prevention of ...
Anna Grzegory, Lech S. Pomorski, Konrad Pagacz, Karol Sieniawski, Krzysztof Kaczka   +4 more
doaj   +1 more source

Alendroninezuur effectiever dan alfacalcidol voor preventie van osteoporose bij patiënten met een reumatische ziekte die starten met glucocorticoïdtherapie [PDF]

, 2007
OBJECTIVE: To compare the effects of alendronate and alfacalcidol in the prevention ofglucocorticoid-related osteoporosis in patients with a rheumatic disease. DESIGN: Randomised, double-blind, double-placebo clinical trial (www.
Buskens, E.; id_orcid, Laan, R.F., Bruyn, G.A., Geusens, P.P., de Nijs, R.N., Lems, W.F., Dijkmans, B.A., Huisman, A.M., Jacobs, J.W., Bijlsmat, J.W., Algra, A., Oostveen, J.C., de Laet, C.E.   +12 more
core   +5 more sources