Results 51 to 60 of about 5,009,966 (344)
An algorithm for the T-countAn algorithm for the T-count
Quantum Information and Computation, 2014 We consider quantum circuits composed of Clifford and $T$ gates. In this context the $T$ gate has a special status since it confers universal computation when added to the (classically simulable) Clifford gates. However it can be very expensive to implement fault-tolerantly.
Michele Mosca +3 more
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BMC Bioinformatics, 2019 Background Literature derived knowledge assemblies have been used as an effective way of representing biological phenomenon and understanding disease etiology in systems biology.
Reagon Karki +3 more
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A machine learning method for the identification and characterization of novel COVID-19 drug targets
Scientific Reports, 2023 In addition to vaccines, the World Health Organization sees novel medications as an urgent matter to fight the ongoing COVID-19 pandemic. One possible strategy is to identify target proteins, for which a perturbation by an existing compound is likely to ...
Bruce Schultz +8 more
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Adaptive Alternating Minimization Algorithms [PDF]
, 2008 The classical alternating minimization (or projection) algorithm has been successful in the context of solving optimization problems over two variables. The iterative nature and simplicity of the algorithm has led to its application to many areas such as
Niesen, Urs +2 more
core +3 more sources
FEBS Letters, EarlyView.Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel +2 more
wiley +1 more source
Analysis of Algorithms and Partial Algorithms [PDF]
, 2016 We present an alternative methodology for the analysis of algorithms, based on the concept of expected discounted reward. This methodology naturally handles algorithms that do not always terminate, so it can (theoretically) be used with partial algorithms for undecidable problems, such as those found in artificial general intelligence (AGI) and ...
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Analysis of an algorithm catching elephants on the Internet [PDF]
Discrete Mathematics & Theoretical Computer Science, 2008 The paper deals with the problem of catching the elephants in the Internet traffic. The aim is to investigate an algorithm proposed by Azzana based on a multistage Bloom filter, with a refreshment mechanism (called $\textit{shift}$ in the present paper),
Yousra Chabchoub +3 more
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Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
, 2017 For genetic algorithms using a bit-string representation of length~$n$, the general recommendation is to take $1/n$ as mutation rate. In this work, we discuss whether this is really justified for multimodal functions. Taking jump functions and the $(1+1)$
Doerr, Benjamin +3 more
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Molecular Oncology, EarlyView.TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam +9 more
wiley +1 more source