Results 71 to 80 of about 9,995,501 (376)
FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
An algorithm for the T-countAn algorithm for the T-count
Quantum Information and Computation, 2014 We consider quantum circuits composed of Clifford and $T$ gates. In this context the $T$ gate has a special status since it confers universal computation when added to the (classically simulable) Clifford gates. However it can be very expensive to implement fault-tolerantly.
Michele Mosca +3 more
openaire +3 more sources
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Soft document clustering using a novel graph covering approach
BioData Mining, 2018 Background In text mining, document clustering describes the efforts to assign unstructured documents to clusters, which in turn usually refer to topics. Clustering is widely used in science for data retrieval and organisation.
Jens Dörpinghaus +2 more
doaj +1 more source
, 2012 Consider the problem when we want to construct some structure on a bounded degree graph, e.g. an almost maximum matching, and we want to decide about each edge depending only on its constant radius neighbourhood.
Csóka, Endre
core
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
KOALA GRAPH THEORY INTERNET SERVICE
TASK Quarterly, 2015 KOALA has been created with the idea of C++ library templates, implementing a broad set of procedures in the fields of algorithmic graph theory and network problems in discrete optimization.
TOMASZ GOLUCH +2 more
doaj +1 more source
Information, 2023 Integrating physical simulation data into data ecosystems challenges the compatibility and interoperability of data management tools. Semantic web technologies and relational databases mostly use other data types, such as measurement or manufacturing ...
Philipp Spelten +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source
Analysis of an algorithm catching elephants on the Internet [PDF]
Discrete Mathematics & Theoretical Computer Science, 2008 The paper deals with the problem of catching the elephants in the Internet traffic. The aim is to investigate an algorithm proposed by Azzana based on a multistage Bloom filter, with a refreshment mechanism (called $\textit{shift}$ in the present paper),
Yousra Chabchoub +3 more
doaj +1 more source