Results 71 to 80 of about 9,890,926 (378)

KOALA GRAPH THEORY INTERNET SERVICE

TASK Quarterly, 2015
KOALA has been created with the idea of C++ library templates, implementing a broad set of procedures in the fields of algorithmic graph theory and network problems in discrete optimization.
TOMASZ GOLUCH, KRZYSZTOF M. OCETKIEWICZ, KRZYSZTOF GIARO   +2 more
doaj   +1 more source

On minimal blocking sets of the generalized quadrangle $Q(4, q)$ [PDF]

Discrete Mathematics & Theoretical Computer Science, 2005
The generalized quadrangle $Q(4,q)$ arising from the parabolic quadric in $PG(4,q)$ always has an ovoid. It is not known whether a minimal blocking set of size smaller than $q^2 + q$ (which is not an ovoid) exists in $Q(4,q)$, $q$ odd. We present results
Miroslava Cimráková, Veerle Fack
doaj   +1 more source

The Elements of Flexibility for Task-Performing Systems

IEEE Access, 2023
What makes living systems flexible so that they can react quickly and adapt easily to changing environments? This question has not only engaged biologists for decades but is also of great interest to computer scientists and engineers who seek inspiration
Sebastian Mayer, Leo Francoso Dal Piccol Sotto, Jochen Garcke   +2 more
doaj   +1 more source

Random local algorithms [PDF]

, 2012
Consider the problem when we want to construct some structure on a bounded degree graph, e.g. an almost maximum matching, and we want to decide about each edge depending only on its constant radius neighbourhood.
Csóka, Endre
core  

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Design and Simulation of a Hierarchical Parallel Distributed Processing Model for Orientation Selection Based on Primary Visual Cortex

Biomimetics, 2023
The study of the human visual system not only helps to understand the mechanism of the visual system but also helps to develop visual aid systems to help the visually impaired.
Hui Wei, Jingyong Ye, Jiaqi Li, Yun Wang
doaj   +1 more source

Algorithms and Bounds for Very Strong Rainbow Coloring

, 2018
A well-studied coloring problem is to assign colors to the edges of a graph $G$ so that, for every pair of vertices, all edges of at least one shortest path between them receive different colors.
Algorithms and Complexity, Bender, Michael A., Chandran, L. Sunil, Das, Anita, Farach-Colton, Martin, Issac, Davis, Leeuwen, Erik Jan van, Mosteiro, Miguel A., Sub Algorithms and Complexity   +8 more
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Comparison and aggregation of event sequences across ten cohorts to describe the consensus biomarker evolution in Alzheimer’s disease

Alzheimer’s Research & Therapy, 2022
Background Previous models of Alzheimer’s disease (AD) progression were primarily hypothetical or based on data originating from single cohort studies. However, cohort datasets are subject to specific inclusion and exclusion criteria that influence the ...
Sepehr Golriz Khatami, Yasamin Salimi, Martin Hofmann-Apitius, Neil P. Oxtoby, Colin Birkenbihl, for the Alzheimer’s Disease Neuroimaging Initiative, the Japanese Alzheimer’s Disease Neuroimaging Initiative, the Alzheimer’s Disease Repository Without Borders Investigators   +7 more
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source