Results 81 to 90 of about 29,783 (290)

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Alimentação da criança com fissura de lábio e/ou palato: um estudo bibliográfico Alimentación del niño com fisura del labio y/o paladar: um estudio bibliográfico Alimentation of children with lip-palate malformation: a bibliographic study

open access: yesRevista Latino-Americana de Enfermagem, 2000
O objetivo deste estudo é descrever a criança portadora de deformação congênita lábio palatal, enfatizando sua alimentação, as dificuldades e os métodos alternativos para alimentar a criança, e assistência de enfermagem neste processo.
Raimunda da Costa Araruna   +1 more
doaj   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini   +11 more
wiley   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Alimentation Influence in the characteristics of compounds related with fat of ham from iberic pigs

open access: yesGrasas y Aceites, 1991
Alimentation influence (acorn, acorn-bait mixed, bait) over characteristics fat and their degradation products, that are in part, responsible of the aroma of ham, has been studied. Influence over the naturation degree has been observed.
J. Melgar   +3 more
doaj   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

Habitude alimentaire des mères pendant la grossesse et l'allaitement, région Amoron'i Mania Madagascar: étude qualitative

open access: yesThe Pan African Medical Journal, 2018
INTRODUCTION: L'alimentation des mères est très importante à cause des besoins nutritionnels spécifiques pour la reproduction. La présente étude vise à décrire les habitudes alimentaires des mères pendant la grossesse et l'allaitement et répertorier les ...
Lantonirina Ravaoarisoa   +4 more
doaj   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

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