Results 211 to 220 of about 42,000 (301)

Bone marrow stromal cells enhance chondrocyte function and autophagy via mTOR signaling. [PDF]

Sci Rep
Yang Y, Zheng Z.
europepmc   +1 more source

Platelet‐Rich Fibrin Induces New Bone Formation to Promote Extreme Lateral Interbody Fusion of Spine in Rabbits

JOR SPINE, Volume 9, Issue 2, June 2026.
Preparation process of PRF and its promotion of intervertebral fusion. The rabbit lateral fusion model proves that PRF can promote the intervertebral fusion rate of allograft bone. In vitro experiments can be observed that PRF promotes the osteogenic expression of BMSCS.
Weijian Wang, Jiaqi Li, Han Wu, Sidong Yang, Shaorong Li, Wei Zhang   +5 more
wiley   +1 more source

Protocol to study the contribution of biomechanics in osteoarthritis development using a cartilage-on-chip model. [PDF]

STAR Protoc
Faure E, Chobaz V, de Haro D, Lauwers E, Busso N, Paggi CA, Nasi S.   +6 more
europepmc   +1 more source

Comparative Analysis of Dual‐miRNA Mediated Stimulation of Nucleus Pulposus and Bone Marrow Derived Stem Cells for Intervertebral Disc Repair

JOR SPINE, Volume 9, Issue 2, June 2026.
Nucleus pulposus (NP) and bone marrow derived stem cells (BMSCs) transfected with miRNA‐149‐5p‐mimic and 221‐3p‐inhibitor were evaluated in goat monolayer, microtissue, and ex vivo organ cultures of mild degeneration. miRNA‐treated NP cells demonstrated an anti‐catabolic and pro‐discogenic response in organs, highlighting its potential as a ...
Tara Ní Néill, Niamh Wilson, Jake McDonnell, Fergal J. O'Brien, Caroline M. Curtin, James E. Dixon, Pieter A. J. Brama, Conor T. Buckley   +7 more
wiley   +1 more source

Pre‐Conditioned Bone Marrow Mesenchymal Stromal Cell‐Derived Secretome Exerts an Anti‐Inflammatory Effect on Degenerative Nucleus Pulposus Cells In Vitro

JOR SPINE, Volume 9, Issue 2, June 2026.
IL‐1β‐preconditioned BM‐MSC‐derived secretome counteracts inflammation‐driven degeneration in hNPCs. BM‐MSCs were preconditioned with IL‐1β (10 ng/mL) for 24 h, and the resulting secretome (BM‐MSCsec) was collected. Degenerative hNPCs cultured in a 3D alginate bead model were exposed to IL‐1β to reproduce an inflammatory degenerative microenvironment ...
Veronica Tilotta, Gianluca Vadalà, Luca Ambrosio, Giuseppina Di Giacomo, Claudia Cicione, Fabrizio Russo, Rocco Papalia, Vincenzo Denaro   +7 more
wiley   +1 more source

DPHD from <i>Curcuma comosa</i> Enhances the Expansion and Osteogenic Differentiation of Human Umbilical Cord-Derived Mesenchymal Stem Cells While Attenuating Senescence. [PDF]

ACS Omega
Boonmuen N, Paing MM, Sutjarit N, Kheolamai P, Manochantr S, Tantrawatpan C, Chaichompoo W, Suksamrarn A, Tantikanlayaporn D.   +8 more
europepmc   +1 more source

3D Printed High‐Strength Hydrogel for Dual Release of Cu2+ and Ag+ Ions to Enhance Bone Repair and Antibacterial Properties

Rare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT Bone restoration is often hindered by the spatiotemporal dysregulation of immune and regenerative signals. Conventional bio‐inert implants, providing only passive support, fail to modulate this microenvironment, leading to infections and poor healing.
Zhizhong Sun, Yifei Wang, Yi Zheng, Minying Li, Longbao Feng, Ziwei Jiang, Hengrui Liu, Rui Guo, Weipeng Sun   +8 more
wiley   +1 more source

YAK577 Attenuates Vascular Calcification by Targeting an MMP14-NOX2/ROS Axis in VSMCs and a Vitamin D₃-Induced Mouse Model. [PDF]

Antioxidants (Basel)
Zhou H, Kee HJ, Jeong SM, Bai L, Wan L, Kim SH, Lee SH, Kurz T, Sim DS, Jeong MH, Hong YJ.   +10 more
europepmc   +1 more source

Lanthanum Chloride in Vascular Calcification: Effects on Nano‐Hydroxyapatite and PPARγ/Wnt/β‐Catenin

FASEB BioAdvances, Volume 8, Issue 6, June 2026.
This study elucidates the anti‐calcification mechanism of lanthanum chloride (LaCl₃) in rats with chronic kidney disease (CKD) and human vascular smooth muscle cells (hVSMCs). Unlike traditional phosphate binders, trace amounts of LaCl₃ can inhibit vascular calcification without lowering serum phosphorus levels.
Ting Zhang, Jialong Qian, Li Zhu, Zhihua Zhou, Xin Wang, Yan Liang, Luyu Wang, Chunsheng Zhang, Ren Bu, Hong Liu, Changjin Xu, Gang Li   +11 more
wiley   +1 more source

Substrate stiffness modulates human gingival fibroblast paracrine signaling to promote osteogenic differentiation of human periodontal ligament cells. [PDF]

Front Bioeng Biotechnol
Tiskratok W, Yamada M, Kyawsoewin M, Lwin HY, Egusa H, Jitprasertwong P, Limraksasin P.   +6 more
europepmc   +1 more source