Results 221 to 230 of about 42,000 (301)

Abnormal Stress Reduced miR‐330 Supplementation Alleviates Osteoarthritis Progression by Suppressing Osteochondral Catabolism

Aging Cell, Volume 25, Issue 6, June 2026.
Downregulation of miR‐330 under abnormal stress exacerbates catabolism in cartilage and subchondral bone, thereby promoting the progression of osteoarthritis. ABSTRACT Abnormal mechanical stress plays a crucial role in the progression of osteoarthritis (OA). Key factors regulating mechanical response remain to be explored. This study harvested synovium
Luxiang Zou, Kaiwen Yang, Chuyao Wang, Yeke Yu, Xiaoyu Zhang, Chuan Lu, Jieyun Zhao, An Qin, Dongmei He   +8 more
wiley   +1 more source

Flavonoids of <i>Cuscuta chinensis</i> Enhance Osteogenic Differentiation in Dental Pulp Stem Cells via the Regulation of Wnt/β-Catenin Signaling. [PDF]

Prev Nutr Food Sci
Yang J, Guo X, Xiao J, Kantawong F.
europepmc   +1 more source

Senescent BMSC‐Derived Thbs1 Drives Inflammaging and Impairs Bone Regeneration by Suppressing PINK1/Parkin‐Mediated Mitophagy in Macrophages

Aging Cell, Volume 25, Issue 6, June 2026.
Aging BMSC‐derived Thbs1 activates the macrophage TGF‐β/Smad3 pathway to transcriptionally repress Pink1, impairing mitophagy and causing mitochondrial ROS accumulation. This redox imbalance drives M1 polarization and IL‐6 secretion. IL‐6 feeds back to BMSCs via the JAK/STAT3 pathway to inhibit osteogenesis and upregulate Thbs1, establishing a self ...
Yifeng Xing, Jingjing Su, Yanjun Lin, Nengwen Huang, Sihui Zhang, Yuwei Zhou, Jie Lu, Weiping Chen, Kaixun He, Wenxiu Yuan, Yang Li, Geyuan Zheng, Pengyuan Hu, Dong Wu, Yanjing Ou, Jiang Chen   +15 more
wiley   +1 more source

Aging‐Related Muscle Bmal1 Decline Contributes to Bone Loss in Mice via Enhancing IL‐1α–Mediated Osteoclastogenesis

Aging Cell, Volume 25, Issue 6, June 2026.
Aging‐related decline of muscle Bmal1 drives bone loss in mice by disrupting Hmox1 and increasing IL‐1α, which promotes osteoclast activity. Time‐restricted feeding reestablishes diurnal Hmox1 expression, reduces IL‐1α, and alleviates osteoporosis, offering a potential therapeutic strategy. ABSTRACT Osteoporosis, a common metabolic bone disorder linked
Kai Huang, Jun Qian, Yike Wang, Feng Zhang, Youjia Xu, Qiaocheng Zhai   +5 more
wiley   +1 more source

Boronic acid affinity media conjugating with PEG enable precise pH-responsive HPLC separation of glycoproteins depending on differences of sugar chains. [PDF]

Sci Rep
Koda K, Konishi-Yamada S, Kubo T.
europepmc   +1 more source

Apolipoprotein C3 exacerbates vascular calcification by promoting ferroptosis via the TLR2/AMPK pathway in vascular smooth muscle cells. [PDF]

Redox Biol
Zhou Z, Chen J, Wang H, Han Y, Liu C, Shen Q, Dong Z, Lu K, Zhai C, Xu Y, Zhang L, He L, Fang Y, Zhang L, Wang Y, Xian X, Yao L, Dong E, Huang W.   +18 more
europepmc   +1 more source

Red era: Dyeing yak hair fibres red with in situ generated silver nanoparticles using silver nitrate and a flavonoid‐containing plant extract

Coloration Technology, Volume 142, Issue 3, Page 439-455, June 2026.
Abstract Plants and their extracts have been used for dyeing fabrics, skin and hair for thousands of years and have been experiencing a revival in the last years due to increasing health risks arising from oxidative hair dye precursors. We developed a novel two‐step method to dye keratin fibres based on in situ formed silver nanoparticles including a ...
Julia K. Hachmann, Jule M. Sauler, Charlotte Ruhmlieb, Volkmar Vill, Fabian Straske   +4 more
wiley   +1 more source

Osteogenic-like Phenotypic Reprogramming Is Associated with Reduced Malignant Behaviors in Pancreatic Cancer Cells Involving MAPK-ERK Signaling. [PDF]

Int J Mol Sci
Chen G, Huang X, Li D, Wei W.
europepmc   +1 more source