Results 111 to 120 of about 96,322 (259)

Immune‐Related Prognostic Gene Identification in Lung Squamous Cell Carcinoma With the Cancer Genome Atlas Mining and Immunohistochemistry Validation

iNew Medicine, EarlyView.
ABSTRACT Objective In the cancer microenvironment, stromal and immune cells hold clinical importance. In lung squamous cell carcinoma (LSCC), the aim of this study was to find immune‐linked gene expression that has prognostic pertinence. Methods From the Cancer Genome Atlas, this study obtained the LSCC gene expression profile.
Weijia Jiang, Jing Xu, Wenwen Ma, Qingjie Zhu, Pawin Pongkorpsakol, Guoping Sun   +5 more
wiley   +1 more source

The frequency of EGFR gene mutations in a cohort of Romanian patients with non-small cell lung cancer and their association with PD-L1 expression level and ALK rearrangements

Romanian Journal of Laboratory Medicine
The mortality rate linked to non-small cell lung cancer (NSCLC) has notably decreased in recent years, primarily due to refined diagnostic techniques.
Cohn Ester-Andreea, Csutak Ortansa, Tataru Ecaterina   +2 more
doaj   +1 more source

Alk: A Formal-Methods-based Educational Platform for Enhancing Algorithmic Thinking [PDF]

Algorithm design courses are fundamental to computer science curricula, but fostering algorithmic thinking in students is challenging due to the diverse skills and creativity required. Dedicated teaching support tools can help both course instructors and
Lucanu, Dorel, Vlad Teodorescu, Dorel Lucanu, Andrei, Oana, Alexandru-Ioan Lungu, Andrei Zaborila, Oana Andrei, Zaborila, Andrei, Teodorescu, Vlad, Lungu, Alexandru-Ioan   +9 more
core   +1 more source

ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential

iNew Medicine, EarlyView.
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang, Xinyan Li, Honglu Shi, Gaolei Song, Zhifu Xie, Jingya Li   +5 more
wiley   +1 more source

Liquid biopsy procedures to detect ALK rearrangements and its secondary mutations in patients with lung adenocarcinoma.

, 2023
reservedIl tumore del polmone è la principale causa di morte per tumore nel mondo con circa 2.2 milioni di nuovi casi e 1.8 milioni di decessi nel 2020 secondo i dati pubblicati su GLOBOCAN[1].
FACCIOLI, GIOVANNI
core  

Drought Risk in Mango and Avocado Orchards: Insights Into Plant Water Relations and Irrigation‐Related Agronomic Solutions

Irrigation and Drainage, EarlyView.
ABSTRACT Climate change is making water availability more uncertain, with growing consequences for the productivity and long‐term sustainability of tropical and subtropical fruit orchards. Mangifera indica L. and Persea americana Mill. both require large amounts of water to sustain growth and productivity.
Eleonora Cataldo
wiley   +1 more source

Reduced Ocular Surface Inflammation in SMILE Patients: The Beneficial Outcome of 0.1% Ciclosporin Cationic Emulsion Treatment

Clinical Ophthalmology
Alex LK Ng,1,2 Douglas KT Lam1,2 1Hong Kong Ophthalmic Associates, Hong Kong SAR, People’s Republic of China; 2Hong Kong Eye Day Surgery Centre, Hong Kong SAR, People’s Republic of ChinaCorrespondence: Alex LK Ng, Hong Kong Ophthalmic Associates, 26/F ...
Ng ALK, Lam DKT
doaj  

A hepatic enigma: Pediatric presentation of primary biliary cholangitis

JPGN Reports, EarlyView.
Abstract Primary biliary cholangitis (PBC) is a chronic autoimmune condition characterized by destruction of intrahepatic bile ducts, leading to fibrosis and cirrhosis of the liver. It is an extremely rare pediatric disease with very few pediatric cases reported to date. Here, we report the case of a 14‐year‐old female who presented with elevated liver
Sindhura Kasturi, Rachel Schenker, Nick Shillingford, George Yanni   +3 more
wiley   +1 more source

Non-small Cell Lung Cancer with Metachronous Mutations of EGFR and ALK Genes: 
A Case Report and Literature Review

Chinese Journal of Lung Cancer
Multiple primary lung cancer (MPLC) refers to patients with two or more primary lesions of lung cancer. It can be divided into synchronous MPLC (sMPLC) and metachronous MPLC (mMPLC) based on the timing of occurrence.
Xiaoyan KONG, Mingjuan WANG, Qiaoyun TANG, Mengyu SUN, Jianjun HU   +4 more
doaj   +1 more source

Hypersensitivity in ALK-positive lung cancers exposed to ALK inhibitors: a case of successful switch to an alternative ALK inhibitor and systematic review of the literature

, 2018
Lei Deng,1 Janaki Sharma,2 Elizabeth Ravera,2 Balazs Halmos,2 Haiying Cheng2 1Department of Medicine, Jacobi Medical Center/Albert Einstein College of Medicine, Bronx, NY, USA; 2Department of Oncology, Montefiore Medical Center/Albert Einstein College of
Halmos B, Deng L, Sharma J, Cheng H, Ravera E   +4 more
core