Results 21 to 30 of about 96,322 (259)

The SQ HDM SLIT‐Tablet is safe and well tolerated in patients with House Dust Mite allergic rhinitis with or without asthma: A “real‐life” French study

Clinical and Translational Allergy, 2022
Background The SQ House Dust Mite (HDM) SubLingual ImmunoTherapy (SLIT)‐Tablet (Acarizax) is the only allergen immunotherapy authorized by European regulatory authorities to treat HDM‐induced allergic asthma (AA) that is not well‐controlled by inhaled ...
Pascal Demoly, Christophe Leroyer, Elie Serrano, Annelore Le Maux, Gabrielle Magnier, Antoine Chartier   +5 more
doaj   +1 more source

Molecular and functional analysis identifies ALK-1 as the predominant cause of pulmonary hypertension related to hereditary haemorrhagic telangiectasia. [PDF]

, 2003
BACKGROUND\ud \ud Mutations of the transforming growth factor beta (TGFbeta) receptor components ENDOGLIN and ALK-1 cause the autosomal dominant vascular disorder hereditary haemorrhagic telangiectasia (HHT).
Flanagan, J A, Gruenig, E, Sankelo, M, Halme, M, Elliott, C G, Laitinen, T, Morrell, N W, Trembath, R C, Räisänen-Sokolowski, A, Olschewski, H, Harrison, R E, Robbins, I M, Kermeen, F, Abdalla, S A, Rowell, J, Machado, R D, McLaughlin, V   +16 more
core   +1 more source

ALK inhibition activates LC3B-independent, protective autophagy in EML4-ALK positive lung cancer cells. [PDF]

, 2021
ALK inhibitors effectively target EML4-ALK positive non-small cell lung cancer, but their effects are hampered by treatment resistance. In the present study, we asked whether ALK inhibition affects autophagy, and whether this may influence treatment ...
Berezowska, Sabina, Schläfli, Anna M, Schläfli, Anna M., Jutzi, S., Berezowska, S., Tokarchuk, I., Engedal, N., Tschan, M.P., Tokarchuk, Igor, Parejo, Sarah, Tschan, Mario P., Parejo, S., Engedal, Nikolai, Jutzi, Susanne, Schläfli, A.M.   +14 more
core   +2 more sources

Self-reported questionnaire survey on the prevalence and symptoms of adverse food reactions in patients with chronic inhalant diseases in Tangshan city, China

Allergy, Asthma & Clinical Immunology, 2018
Background The prevalence of adverse food reactions in patients with chronic inhalant diseases has seldom been studied in China. This study is to investigate the prevalence of adverse food reactions and the symptoms caused in respiratory patients ...
Guodong Hao, Xuxin Lai, Zhijing Song, Zhixing Wang, Xing-ai Kong, Haifeng Zhong, Sui Fu Hui, Yiwu Zheng   +7 more
doaj   +1 more source

F-18 FDG PET/CT characterization and predictive efficacy for driver mutation positive and negative pulmonary adenocarcinoma in correlation with clinico-pathologic data

National Board of Examinations Journal of Medical Sciences, 2023
Background: Fluorine-18 (isotope)-Fluoro-deoxyglucose positron emission tomography computed tomography (F-18-FDG PET/CT) as a non-invasive method could predict driver mutation status in pulmonary adenocarcinoma.
Ashish Acharya K, Shelley Simon, Indirani M   +2 more
doaj   +1 more source

Investigating ALK inhibitors alone or in combination as therapeutic options for ALK-positive neuroblastoma [PDF]

, 2021
Neuroblastoma (NBL) is the third most common pediatric cancer after leukemia and cranial tumours and accounts for around 15% of death in pediatric malignancy.
Alam, Muhammad Wasi
core   +1 more source

Resonance reliability and importance measure analysis of multi-span pipe conveying fluid embedded in temperature-varying matrix

Xibei Gongye Daxue Xuebao, 2021
Pipe system conveying fluid faces the problem of multi-order resonance failure caused by broadband excitation. For solving above problem, the dynamic stiffness method is employed to solve the dynamic equations of multi-span pipes considering the ...
WU Nan, GUO Qing, TONG Guojun, LIU Yongshou   +3 more
doaj   +1 more source

The impact of perennial allergic rhinitis with/without allergic asthma on sleep, work and activity level

Allergy, Asthma & Clinical Immunology, 2019
Background Allergic respiratory diseases such as allergic rhinitis (AR) and allergic asthma (AA) are common conditions that can influence sleep and daytime functioning. However, the significance of this impact is unclear—particularly in perennial allergy
Mercedes Rodriguez Romano, Stephanie James, Emily Farrington, Richard Perry, Lisa Elliott   +4 more
doaj   +1 more source

The Effect of Cement Dust on the Activity of GOT , GPT and ALK Enzymes in Al-Qaim Cement Factory Workers [PDF]

مجلة جامعة الانبار للعلوم الصرفة, 2012
This research was conducted on a random sample of (58) individuals , (38) of them were directly exposed to cement dust . They were distributed according to units into (9) in oven department , (17) individuals in cement grinding department and (12) in ...
Ziad Khazer Abdul Razaaq, Haitham Latef Abd, Mustafa Nuhad Jumaa   +2 more
doaj   +1 more source

Research Progress of Proteolysis Targeting Chimeria in NSCLC Therapy

Chinese Journal of Lung Cancer, 2022
Proteolysis targeting chimeria (PROTAC) degrades target proteins by utilizing the ubiquitin-proteasome pathway, subverting the concept of traditional small molecule inhibitors.
Lin JIANG, Jingbo ZHANG, Jiaqi HU, Haixiang QI, Heng XU   +4 more
doaj   +1 more source