Results 121 to 130 of about 1,135,160 (396)

Bone Healing Around Implants in Normal and Medically Compromised Conditions: Osteoporosis and Diabetes

open access: yesAdvanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello   +2 more
wiley   +1 more source

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

open access: yesAdvanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach   +7 more
wiley   +1 more source

Experimental investigation of taxon‐specific response of alkaline phosphatase activity in natural freshwater phytoplankton [PDF]

open access: bronze, 2003
Karin Rengefors   +5 more
openalex   +1 more source

3D‐Printed Titanium Implants with Bioactive Peptide‐Polysaccharide Scaffolds for Personalized Bone Reconstruction

open access: yesAdvanced Healthcare Materials, EarlyView.
Porous 3D‐printed titanium implants are made bioactive by integration with a supramolecular peptide‐hyaluronic acid nanofibrillar scaffold, without the addition of exogenous cells or growth factors. Uniform filling of the implant architecture promotes vascularized, spatially homogeneous bone regeneration, significantly enhancing osteogenesis throughout
Noam Rattner   +8 more
wiley   +1 more source

Multiple fractures, pain, and severe disability in a patient with adult-onset hypophosphatasia

open access: yesBone Reports, 2016
Hypophosphatasia (HPP) is a rare, inherited metabolic bone disease resulting from mutations in the gene encoding tissue non-specific alkaline phosphatase.
Neil A. Braunstein
doaj   +1 more source

GP211 Positive correlation of serum alkaline phosphatase and serum alanine transaminase with the abundance-based indices of the microbiota in obese adolescents [PDF]

open access: bronze, 2019
Л. В. Рычкова   +5 more
openalex   +1 more source

Alkaline Phosphatase Levels as a Predictor of Neonatal Hyperbilirubinemia

open access: gold, 2022
Rani Saba Urooj   +6 more
openalex   +2 more sources

Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics

open access: yesAdvanced Materials, EarlyView.
This review summarizes the current status of polymeric, ceramic, and metallic absorbable materials in orthopedic applications, and highlights several innovative strategies designed to enhance mechanical performance, control degradation, and promote bioactivity. We also discuss the progress and translational potential of absorbable materials in treating
Zhao Wang   +13 more
wiley   +1 more source

A Pseudo‐Mytilus Edulis Foot Protein‐Based Hydrogel Adhesive with Osteo‐Vascular‐Immune Coupling Effects for Osteoporotic Bone‐Implant Integration

open access: yesAdvanced Materials, EarlyView.
Inspired by mussel proteins, YDC‐Gel‐Zn is a smart bone glue designed for osteoporotic implants. It adheres strongly to both metal implants and bone for initial fixation. In osteoporosis's inflammatory environment, it sequentially releases zinc ions and therapeutic peptides: the zinc modulates immune cells to reduce inflammation, while the peptides ...
Wentao Wang   +9 more
wiley   +1 more source

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