Research Progress of Alkaline Phosphatase and Its Activity in the Ocean
This paper reviewed the research progress and prospects of alkaline phosphatase and its activity in the ocean, aiming to better understand marine biogeochemical cycles and ecosystem functions and provide a scientific basis for related research topics ...
Xianrui SONG, Hui SONG, Dan WANG, Bei SU
doaj
Probable levetiracetam-related serum alkaline phosphatase elevation
Background Levetiracetam (LEV) is an antiepileptic drug with a favorable tolerability and safety profile with little or no effect on liver function. Case presentation Here, we reported an epileptic pediatric patient who developed a significant elevation ...
Xiong Nian+5 more
doaj +1 more source
The stochastic behavior of a molecular switching circuit with feedback [PDF]
Background: Using a statistical physics approach, we study the stochastic switching behavior of a model circuit of multisite phosphorylation and dephosphorylation with feedback. The circuit consists of a kinase and phosphatase acting on multiple sites of a substrate that, contingent on its modification state, catalyzes its own phosphorylation and, in a
arxiv
Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania+2 more
wiley +1 more source
Membrane topology of the ArsB protein, the membrane subunit of an anion-translocating ATPase [PDF]
The ars operon of the conjugative R-factor R773 encodes an oxyanion pump that catalyzes extrusion of arsenicals from cells of Escherichia coli. The oxyanion translocation ATPase is composed of two polypeptides, the catalytic ArsA protein and the ...
Rosen, Barry P.+2 more
core +1 more source
HISTOLOGICAL AND HISTOCHEMICAL EVALUATION OF NORMOTENSIVE AND PREECLAMPTIC PLACENTAS
The placenta plays a role in the pathophysiology of preeclampsia. Preeclampsia is more common in multifetal pregnancies than singleton pregnancies. In this study, we aimed to investigate the histopathology of normotensive and preeclamptic placentas and ...
Gamze ERDOĞAN
doaj +1 more source
Regions of multistationarity in cascades of Goldbeter-Koshland loops [PDF]
We consider cascades of enzymatic Goldbeter-Koshland loops with any number n of layers, for which there exist two layers involving the same phosphatase. Even if the number of variables and the number of conservation laws grow linearly with n, we find explicit regions in reaction rate constant and total conservation constant space for which the ...
arxiv
Accelerated Bone Healing via Electrical Stimulation
Electrical stimulation significantly impacts bone healing by enhancing osteoblast proliferation, differentiation, and vascularization through calmodulin/calcineurin/NFAT signaling. It also boosts macrophage function and cell migration, presenting a comprehensive approach to accelerating bone repair.
Jianfeng Sun+4 more
wiley +1 more source
Greatwall-phosphorylated Endosulfine is Both an Inhibitor and a Substrate of PP2A-B55 Heterotrimers [PDF]
During M phase, Endosulfine (Endos) family proteins are phosphorylated by Greatwall kinase (Gwl), and the resultant pEndos inhibits the phosphatase PP2A-B55, which would otherwise prematurely reverse many CDK-driven phosphorylations. We show here that PP2A-B55 is the enzyme responsible for dephosphorylating pEndos during M phase exit.
arxiv
Electrical Microneedles for Wound Treatment
A review on state‐of‐art research concerning electrical microneedles applied for wound treatment is presented. After a comprehensive analysis of mechanisms of electrical stimulation on wound healing, the derived three types of electrical microneedles are clarified and summarized. Further, their applications in wound healing are highlighted.
Yu Wang+6 more
wiley +1 more source