Results 161 to 170 of about 333,892 (266)

Association of alkaline phosphatase to platelet ratio index with ICU mortality in patients with cardiac arrest. [PDF]

BMC Cardiovasc Disord
Li Y, Lin Z, Chen Y, Di X, Zhou F, Xia Y, Zhang P, Tang J, Liu Y, Wang X, Yuan Y, Zhao Y.   +11 more
europepmc   +1 more source

Prediction of Long‐Term Prognosis in Patients With Hepatocellular Carcinoma Using the National Clinical Database Risk Calculator

Annals of Gastroenterological Surgery, EarlyView.
This study aimed to determine the value of the National Clinical Database (NCD) risk calculator in predicting surgical outcomes and long‐term prognosis in patients undergoing resection for hepatocellular carcinoma (HCC). We retrospectively analyzed data from 210 patients with HCC who underwent initial hepatic resection, assessing the relationship ...
Mariko Tsukagoshi, Kenichiro Araki, Norio Kubo, Takamichi Igarashi, Shunsuke Kawai, Kei Hagiwara, Kouki Hoshino, Ryo Muranushi, Ken Shirabe   +8 more
wiley   +1 more source

Tissue nonspecific and intestinal alkaline phosphatase crosstalk: a missing link in hypophosphatasia pathophysiology? [PDF]

J Transl Med
Martínez-Heredia L, González-Cejudo T, Andreo-López MC, Contreras-Bolívar V, García-Fontana C, García-Fontana B, Muñoz-Torres M.   +6 more
europepmc   +1 more source

AS‐pHopt: An Optimal pH Prediction Model Enhanced by Active Site of Enzymes

Advanced Intelligent Discovery, EarlyView.
To address the low accuracy of enzyme optimal pH (pHopt) prediction, this study develops active site‐based pHopt (AS‐pHopt), a prediction model enhanced by active site information and pseudo‐label prediction. Integrating key structural and physicochemical features affecting enzyme pHopt, AS‐pHopt uses Evolutionary Scale Modeling (ESM)‐2 with active ...
Wenxiang Song, Xinmin Li, Hongbo Yu, Le Xiong, Guixia Liu, Weihua Li, Yun Tang   +6 more
wiley   +1 more source

Persistently low serum alkaline phosphatase in adults: prevalence and clinical characteristics in a large tertiary care hospital. [PDF]

Orphanet J Rare Dis
Alshahrani F, Alsuliman S, Alkalefah R, Almutairi S, Aleidi Y, Almohaya M.   +5 more
europepmc   +1 more source

Concurrent Germline RB1 & Mosaic TP53 in a Child With Multiple Childhood Cancers

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT We report a patient with a pathogenic germline variant (PGV) in RB1 and somatic mosaicism for a pathogenic TP53 variant who developed three distinct types of childhood cancer: retinoblastoma, osteosarcoma, and myelodysplastic syndrome (MDS) before the age of 6 years.
Ole Haubjerg Nielsen, Ulrik Kristoffer Stoltze, Pernille Axél Gregersen, Marianne Hoffmann, Morten Lyng Høgild, Mette Klarskov Andersen, Lise Barlebo Ahlborn, Lisa Lyngsie Hjalgrim, Karin A. W. Wadt   +8 more
wiley   +1 more source

Association between body mass index and rheumatoid arthritis: Exploring a possible role for alkaline phosphatase. [PDF]

Medicine (Baltimore)
Wei W, Xu J.
europepmc   +1 more source

1,2‐propanediol reformulation improves tribromoethanol safety and reveals pontine GABRA1 enrichment as a candidate mechanistic correlate of anesthesia

Animal Models and Experimental Medicine, EarlyView.
This study develops a reformulated tribromoethanol (TBE) anesthetic using 1,2‐propanediol as a solvent to overcome solvent‐related toxicity. The novel formulation demonstrates, cardiovascular stability, and survival in prolonged protocols. It provides potent, dose‐dependent anesthesia without strain or sex differences.
Xia Li, Yanming Chen, Xinyi Xiao, Guoheng Xu   +3 more
wiley   +1 more source

Association of alkaline phosphatase and segmented neutrophils count with low appendicular lean mass in middle-aged women: Evidence from an American cross-sectional survey. [PDF]

J Frailty Aging
Yang S, Wang J, Kim D, Xu H, Zhou S, Yang F, Bao Z.   +6 more
europepmc   +1 more source