Results 121 to 130 of about 294,987 (360)

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

Dutch survey pyrrolizidine alkaloids in animal forage [PDF]

Pyrrolizidine alkaloids (PAs) are secondary plant metabolites produced by a number of plants from the Asteraceae (Compositae), Boriginaceae and Fabaceae (Leguminosae) families.
Beumer, B., Jong, J., de, Mulder, P.P.J., Oosterink, J.E.   +3 more
core   +1 more source

Harnessing Piezoelectric Biomaterials for Pathogenic Eradication and Tissue Regeneration

Exploration, EarlyView.
This review highlights recent advances in piezoelectric biomaterials for antibacterial therapy and tissue regeneration, discussing material classifications, catalytic mechanisms, property enhancements, biomedical applications, and future challenges in clinical translation.
Wenxuan Mao, Xiaoye Li, Ao He, Meng Ding, Yu Zhang, Zhuo Dai, Qiang Li, Weijun Xiu, Yanling Hu, Yongbin Mou, Dongliang Yang, Heng Dong   +11 more
wiley   +1 more source

Chitosan‐Based pH‐Responsive Films and Edible Coatings to Enhance Fruit Shelf‐Life: Impact of Plant Biomolecules and Composition

Food Chemistry International, EarlyView.
Chitosan based coatings/films forming solution with the use ofplant extracts and parameters for fruit shelf life analysis. ABSTRACT Fresh fruits are a natural source of various minerals and vitamins, which are essential for human health. However, a rapid rate of respiration, water loss and fast ripening ability result in shorter shelf life and ...
Arun K. Singh
wiley   +1 more source

Aloe vera Tannin Ameliorates Fructose‐Induced Dyslipidaemia and Oxidative Stress in Wistar Rats

Food Chemistry International, EarlyView.
Aloe vera tannin (AVT) significantly enhances liver reduced glutathione and superoxide dismutase activities in rats. Fructose consumption creates dyslipidaemia in rats by significantly increasing serum cholesterol and LDL levels. AVT prevented fructose‐induced dyslipidaemia in rats by controlling the lipid profile. AVT did not affect liver, hippocampus
Nathan Isaac Dibal, Fatimah Buba, Luteino Lorna Hamman, Sunday Joseph Manye, Zainab Abubakar Abdullahi, Nafisah Ibrahim Umar, Usman Aliyu, Abdulhamid Mahmud, Naim Muazu, Yahaya Musa Dugje, Patience Friday, Yakubu Garba Bilyaminu, Hadiza Ali Makinta   +12 more
wiley   +1 more source

Nutritional Potential, Phytochemical Content, In Vivo Antioxidant, and Antanemic Potential of Musa paradisiaca Flower

Food Chemistry International, EarlyView.
After collecting Musa paradisiaca leaves, some were dried and others were used to produce aqueous extracts. The extracts and powders were characterized and then administered to rats made anaemic by PHZ. After 14 days of administration of the two samples, the rats were euthanized and it was observed that after 9 days of treatment, the aqueous extract ...
Josée Rebeca Nombo, Jethro Roland Misse Ngangue Ekwala, Somon Régine Tuem, Stéphano Tene Tambo, Merlin Ngafon Nchoutpouen, Valery Jean François Nsoga, Jules Christophe Koule Manz, Jordan Mekui Nwotue, Mathieu Ndomou   +8 more
wiley   +1 more source

Bioactive Alkaloids from the Mangrove-Derived Fungus Nigrospora oryzae SYSU-MS0024

Marine Drugs
Chemical investigation of marine fungus Nigrospora oryzae SYSU-MS0024 cultured on solid-rice medium led to the isolation of three new alkaloids, including a pair of epimers, nigrosporines A (1) and B (2), and a pair of enantiomers, (+)-nigrosporine C (+)-
Xiaokun Chen, Senhua Chen, Heng Guo, Xin Lu, Hongjie Shen, Lan Liu, Li Wang, Bin Chen, Yi Zhang, Yayue Liu   +9 more
doaj   +1 more source

Hepatotoxicity induced by greater celandine (Chelidonium majus L.): a review of the literature [PDF]

, 2017
The available literature assessing Chelidonium majus L. (CM) hepatotoxicity potential, and its risk to benefit assessment has been reviewed in this paper.
Busardò, F. P, DI LUCA, Natale Mario, Gentili, S, Graziano, Silvia, Mannocchi, Giulio, Marinelli, Enrico, Pantano, Flaminia   +6 more
core  

Integrated Anatomical, Chemical, Biological and Computational Studies Approach of Myrcia sylvatica (G. Mey) DC. A Multifaceted Insight Into a Promising Amazonian Species

Flavour and Fragrance Journal, EarlyView.
This study presents an integrated anatomical, chemical, biological, and computational analysis of Myrcia sylvatica, revealing key bioactive compounds with antioxidant and toxicological potential, and identifying spathulenol and globulol as promising acetylcholinesterase inhibitors with favourable pharmacokinetic properties. ABSTRACT Myrcia sylvatica (G.
Eliza de Jesus Barros dos Santos, Zelina Ataíde Correia, Ely Simone Cajueiro Gurgel, Leonardo Souza da Costa, Mabrouk Horchani, Hayet Edziri, Ravendra Kumar, Anderson de Santana Botelho, Karyme do Socorro de Souza Vilhena, Eloisa Helena de Aguiar Andrade, Mozaniel Santana de Oliveira   +10 more
wiley   +1 more source

Benzylisoquinoline Biosynthesis by Cultivated Plant Cells and Isolated Enzymes [PDF]

, 1985
Amann, Manfred, Deus-Neumann, Brigitte, Nagakura, Naotaka, Rüffer, Martina, Zenk, Meinhart H.   +4 more
core   +1 more source