Results 171 to 180 of about 225,386 (346)

A new process for the separation of the opium alkaloids [PDF]

, 1887
P. C. Plugge
openalex   +1 more source

Development of a Highly Selective Synthesis of 4‐Substituted Tetrahydroquinolines: Substrate Scope and Mechanistic Study

Chemistry – A European Journal, EarlyView.
A general and selective deprotonation capture sequence of tetrahydroquinolines with alkyl halides and aromatic halides at the 4‐position using organolithiums and phosphoramide ligands is described. Mechanistic and site‐selectivity investigations revealed the active metalation species to be a separated ion pair of which allowed for common directing ...
Jeanette Piña, Lupita S. Aguirre, Levi T. Litwiller, Hai T. Ly, Michael P. Crockett, Andy A. Thomas   +5 more
wiley   +1 more source

Fused Nitrogen Bridgehead N,O‐Acetals as Versatile Scaffolds: Synthetic Strategies, Mechanism and Applications

Chemistry – A European Journal, EarlyView.
Fused nitrogen‐bridgehead N,O‐acetals receive specific emphasis as pivotal scaffolds due to their significant role in the bioactivity of medicinally relevant molecules. Significant approaches have been reported on their role as key synthetic building blocks/motifs in the construction of complex organic molecules and their utility as chiral auxiliaries ...
Alexis D. Kouvelas, Michael G. Kallitsakis, Ioannis N. Lykakis   +2 more
wiley   +1 more source

Distant precursors of benzylisoquinoline alkaloids and their enzymatic formation [PDF]

, 1987
Rüffer, Martina, Zenk, Meinhart H.
core   +1 more source

The Synthesis of Hydroquinolines from Nitroaldehydes and Ketones by Hydrogenation Sequences and Condensations

Chemistry – A European Journal, EarlyView.
We report here a novel complex chemical reaction namely the synthesis of hydroquinolines starting from nitroaldehydes and ketones and hydrogen. The nitroaldehyde is selectively hydrogenated forming an aminoaldehyde, followed by a base‐catalyzed condensation leading to a quinoline intermediate and selective quinoline hydrogenation.
Christof Bauer, Fatemeh Zareh, Lisa Nüßlein, Johanna Frank, Maxime Boniface, Thomas Lunkenbein, Rhett Kempe   +6 more
wiley   +1 more source

THE ERGOT ALKALOIDS

, 1934
Walter A. Jacobs, Lyman C. Craig
openalex   +1 more source

Palatability of N-Oxides of Pyrrolizidine Alkaloids as a Factor in Senecio Poisoning [PDF]

, 1955
R. Schoental
openalex   +1 more source

Efficient and Rapid Arylation of NH₂‐Unprotected Bromobisindole Ethanamines via Suzuki‐Miyaura Coupling: Generating New Leads against Leishmania

Chemistry – A European Journal, Accepted Article.
Leishmaniasis is a neglected tropical disease which presents significant global health challenges due to the lack of effective vaccines and the limitations of existing chemotherapeutics in view of their toxicity, resistance, and high costs. In this study, we realized a library of novel bisindole derivatives as potential anti‐leishmanial agents through ...
Alessandro Buono, Aurora Diotallevi, Sara Maestrini, Michele Verboni, Paula Kiuru, Luca Galluzzi, Andrea Duranti, Diego Olivieri, Simone Lucarini   +8 more
wiley   +1 more source

The Position of the Primary Amino Group in the Steroidal Alkaloid Solanocapsine. [PDF]

, 1959
Per M. Boll, H. A. Lillevik, M. Trætteberg   +2 more
openalex   +1 more source

Integrating Catalysis and Analysis: Accelerated Asymmetric Reaction Development with a Multitasking Reactivity Umpolung/Chiroptical Reporter Auxiliary

Chemistry – A European Journal, Accepted Article.
High‐throughput asymmetric reaction development of an organocatalytic Michael addition is achieved by using a readily available isatin molecule as amine protecting group, reagent for reactivity Umpolung, and as chiroptical yield and enantioselectivity reporter.
F Safia Kariapper, Maria Bouda, Christian Wolf   +2 more
wiley   +1 more source