Results 41 to 50 of about 390,408 (384)

Optimized genotyping method for identification of bacterial contaminants in pharmaceutical industry

open access: yesActa Pharmaceutica, 2016
Microbiological control is of crucial importance in the pharmaceutical industry regarding the possible bacterial contamination of the environment, water, raw materials and finished products. Molecular identification of bacterial contaminants based on DNA
Stamatoski Borche   +4 more
doaj   +1 more source

Recent Discovery of Heterocyclic Alkaloids from Marine-Derived Aspergillus Species

open access: yesMarine Drugs, 2020
Nitrogen heterocycles have drawn considerable attention due to of their significant biological activities. The marine fungi residing in extreme environments are among the richest sources of these basic nitrogen-containing secondary metabolites. As one of
Kuo Xu   +3 more
doaj   +1 more source

Detection of substrate binding motifs for morphine biosynthetic pathway intermediates in novel wound inducible (R,S)-reticuline 7-O-methyltransferase of Papaver somniferum [PDF]

open access: yes, 2011
The benzylisoquinoline alkaloids (BIA) comprise a large and diverse group of nitrogen-containing secondary metabolites with about 2500 compounds identified in plants.
Abha Meena   +5 more
core   +2 more sources

Development and Validation of Discriminative Dissolution Method for Metformin Immediate-Release Film-Coated Tablets

open access: yesJournal of Analytical Methods in Chemistry, 2019
The purpose of this study was to develop and validate a discriminative dissolution method for the metformin film-coated tablet with immediate release of the active substance that belongs to class III of the Biopharmaceutical Classification System (BCS ...
Ivana Mitrevska   +5 more
doaj   +1 more source

Poison Frog Colors Are Honest Signals Of Toxicity, Particularly For Bird Predators [PDF]

open access: yes, 2012
Antipredator defenses and warning signals typically evolve in concert. However, the extensive variation across taxa in both these components of predator deterrence and the relationship between them are poorly understood.
Cummings, Molly E., Maan, Martine E.
core   +3 more sources

Development of chromatographic methods for thebaine detection and quantification along with some of related alkaloid derivatives

open access: yesMacedonian Journal of Chemistry and Chemical Engineering, 2015
Thebaine is naturally occurring alkaloid  which is of great importance in the pharmaceutical industry and  up to now there is not a Pharmacopoeial monograph for this compound.
Marija Spasevska   +2 more
doaj   +1 more source

Paravasation with cyclophosphamide - Case report of tissue necrosis in a patient with primary breast cancer [PDF]

open access: yes, 2007
Background: Paravasation is a rare but severe complication of treatment with cytotoxic agents. Some anticancer drugs are considered to be of high toxicity (vesicant), some are merely irritant, and some are regarded as nearly non-toxic to healthy tissue ...
Adami NP   +7 more
core   +1 more source

Plant-Symbiotic Fungi as Chemical Engineers: Multi-Genome Analysis of the Clavicipitaceae Reveals Dynamics of Alkaloid Loci

open access: yesPLoS Genetics, 2013
The fungal family Clavicipitaceae includes plant symbionts and parasites that produce several psychoactive and bioprotective alkaloids. The family includes grass symbionts in the epichloae clade (Epichloë and Neotyphodium species), which are ...
C. Schardl   +54 more
semanticscholar   +1 more source

Phenotypic plasticity in a novel set of EGFR tyrosine kinase inhibitor‐adapted non‐small cell lung cancer cell lines

open access: yesFEBS Open Bio, EarlyView.
Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy