Results 71 to 80 of about 287,843 (358)

S-adenosyl-l-methionine: (S) -7,8,13, 14-tetrahydroberberine--n-methyltransferase, a branch point enzyme in the biosynthesis of benzophenanthridine and protopine alkaloids. [PDF]

, 1986
The enzyme which transfers the CH3-group of S-adenosylmethionine to the nitrogen atom of (S)-tetrahydroberberine and (S)-stylopine is found to occur in a number of plant cell cultures originating from species containing alkaloids; it is located at an ...
Amann, Battersby, M Rueffer, M.H Zenk, Rueffer, Rueffer, Slavik, Takao, Takao   +8 more
core   +1 more source

Self‐Assembled Dictamni Cortex Nanoparticles Ameliorate Psoriasis by Epigenetic Modulation of HSP90AB1 and Suppression of the Inflammatory Response

Advanced Science, EarlyView.
This study develops self‐assembled Dictamni Cortex (BXP)‐Fe(III) infinite coordination polymer nanoparticles (NB) to improve BXP's solubility and bioavailability for psoriasis. NB transdermally treats psoriasis by targeting the epigenetic regulator CTCF (CCCTC‐binding factor), suppressing HSP90AB1 (heat shock protein 90 alpha family class B member 1 ...
Zhengyi Zhang, Wenqian Du, Xiaojiang Zhang, Hongbo Cui, Baochen Cheng, Xiao Han, Ke He, Tingyi Yin, Xinyi Liu, Ningyi Xian, Ziyang Wang, Meng Liu, Dan Han, Jiankang Liu, Yan Zheng, Ya Wang   +15 more
wiley   +1 more source

Total Synthesis of Calyciphylline F

Angewandte Chemie, EarlyView.
The final challenge in the total synthesis of the caged polycyclic Daphniphyllum alkaloids was the Calyciphylline D‐type alkaloid, featuring a strained 8‐azatricyclo[4.2.1.04,8]nonane ring system. Presented herein is the total synthesis of calyciphylline F, a member of the calyciphylline D‐type alkaloid family, by an intramolecular [4 + 3 ...
Ryota Sato, Ryuichi Sumida, Masaki Inoue, Ryota Kotaka, Sangita Karanjit, Kosuke Namba   +5 more
wiley   +2 more sources

Antidiabetic and antimicrobial activities of fractions and compounds isolated from Berberis brevissima Jafri and Berberis parkeriana Schneid [PDF]

, 2013
Methanol extracts of the roots of B. brevissima and B. parkeriana were examined for antidiabetic and antimicrobial activities. Six compounds i.e berberine, 8-oxo-berberine, dehydrocheilanthifoline, columbamine, jatrorrhizine and glutamic acid were ...
Ali, Saqib, Almazeb, Muhammad, Clements, Carol, Ferro, Valerie, Gray, Alexander, Igoli, John, Khan, M Rafiullah, Rashid, Mamoon-Ur, Semaan, Dima, Shah, Syed Qaisar   +9 more
core   +1 more source

A Modular Chemoenzymatic Cascade Simplifies Divergent Synthesis of Natural and Unnatural Benzylisoquinoline Alkaloids

Advanced Science, EarlyView.
A simplified chemoenzymatic platform is designed to integrate an enzyme cascade with subsequent chemical steps, enabling the divergent production of diverse benzylisoquinoline alkaloids (BIAs). Demonstrating remarkable versatility and enantioselectivity, four distinct classes of BIAs are efficiently generated, in which the natural medicine papaverine ...
Huiling Liu, Zhenbo Yuan, Yue Gao, Fei Li, Zhiwei Deng, Yan Zhang, Zhengshan Luo, Changmei Liu, Yijian Rao   +8 more
wiley   +1 more source

Protective Effects of Alkaloid Compounds from Nelumbinis Plumula on tert-Butyl Hydroperoxide-Induced Oxidative Stress

Molecules, 2013
This study was conducted to investigate the effect of Nelumbinis Plumula total alkaloid (NPA) and its main alkaloid components on oxidative stress induced by tert-butyl hydroperoxide (t-BHP) in the human hepatocellular HepG2 cell line.
Ze-Bin Guo, Bao-Dong Zheng, Shao-Xiao Zeng, Long-Tao Zhang, Yi Zhang, Yong Xie   +5 more
doaj   +1 more source

Hazards to golden-mantled ground squirrels and associated secondary hazard potential from strychnine baiting for forest pocket gophers [PDF]

, 1984
Radio telemetry and capture-recapture techniques were used to evaluate the hazards to golden-mantled ground squirrels (Spermophilus lateralis) from hand baiting with 0.5% strychnine-treated oats for western pocket gophers (Thomomys mazama) on conifer ...
Anthony, R. Michael, Evans, James, Lindsey, Gerald D.   +2 more
core  

Medicago Sativa L. Saponin‐Driven Lactobacillus Intestinalis Restores Intestinal Stemness in Naturally Aged Mice via the Bile Acid‐FXR‐Wnt Signaling Axis

Advanced Science, EarlyView.
This study examines the mechanism by which alfalfa saponin (AS) regulates intestinal stemness via modulation of the gut microbiota. The results indicate that AS significantly increases the abundance of Lactobacillus intestinalis, which subsequently activates Wnt signaling via bile acid metabolism and enhances intestinal stemness. These findings provide
Mengqi Liu, Jiamin Sun, Zuyang Jia, Yalei Cui, Xiaoyan Zhu, Zhichang Wang, Hao Sun, Boshuai Liu, Yinghua Shi   +8 more
wiley   +1 more source

Мultivariate analysis for rapid screening and prediction of solid-state compatibility in pharmaceutical preformulation studies-paving the road for machine learning

Macedonian Journal of Chemistry and Chemical Engineering
Multivariate analysis models were developed to evaluate the results obtained from a compatibility study designed for ibuprofen with a large group of different types of excipients, as a possible approach for rapid screening of the incompatibility between
Elena Cvetkovska Bogatinovska, Nikola Geškovski, Gjorgji Petrushevski, Viktor Stefov   +3 more
doaj   +1 more source

Phytochemical Content and Antioxidant Activity in Tradisional Balinese Babi-guling Spices [PDF]

, 2011
The traditional Balinese richly spiced swine-grill (Babi-guling) has been increasingly popular even among both the domestic and foreign tourists. The traditional grill is very unique in taste as it contains two main components, i.e.
Indraguna Pinatih, G N, Muliartha, I. (IKG), Santosa, A. (A), Suryadhi, N. (NT)   +3 more
core