Results 21 to 30 of about 435,947 (354)

Recent Updates on Marine Cancer-Preventive Compounds

open access: yesMarine Drugs, 2021
The natural compounds derived from marine organisms often exhibit unique chemical structures and potent biological activities. Cancer-preventive activity is one of the rather new activities that has emerged and been extensively studied over the last ...
Sergey A. Dyshlovoy
doaj   +1 more source

Biosynthesis of medicinal tropane alkaloids in yeast

open access: yesNature, 2020
Tropane alkaloids from nightshade plants are neurotransmitter inhibitors that are used for treating neuromuscular disorders and are classified as essential medicines by the World Health Organization 1 , 2 .
P. Srinivasan, C. Smolke
semanticscholar   +1 more source

Stereocontrolled enantioselective total synthesis of the [2+2] quadrigemine alkaloids. [PDF]

open access: yes, 2015
A unified strategy for enantioselective total synthesis of all stereoisomers of the 2+2 family of quadrigemine alkaloids is reported. In this approach, two enantioselective intramolecular Heck reactions are carried out at the same time on precursors ...
Canham, Stephen M   +6 more
core   +4 more sources

Alkaloids in Marine Algae

open access: yesMarine Drugs, 2010
This paper presents the alkaloids found in green, brown and red marine algae. Algal chemistry has interested many researchers in order to develop new drugs, as algae include compounds with functional groups which are characteristic from this particular ...
Ekrem Sezik   +2 more
doaj   +1 more source

Alkaloid content variability in the seeds of narrow-leafed lupine accessions from the VIR collection under the conditions of the Russian Northwest

open access: yesВавиловский журнал генетики и селекции, 2023
Alkaloid content was assessed in the seeds of 59 narrow-leafed lupine (Lupinus angustifolius L.) accessions from the VIR collection in the environments of Leningrad Province.
M. A. Vishnyakova   +4 more
doaj   +1 more source

The Trypanosoma cruzi enzyme TcGPXI is a glycosomal peroxidase and can be linked to trypanothione reduction by glutathione or tryparedoxin. [PDF]

open access: yes, 2002
Trypanosoma cruzi glutathione-dependent peroxidase I (TcGPXI) can reduce fatty acid, phospholipid, and short chain organic hydroperoxides utilizing a novel redox cycle in which enzyme activity is linked to the reduction of trypanothione, a parasite ...
Docampo   +56 more
core   +3 more sources

Bioactive Alkaloids as Secondary Metabolites from Plant Endophytic Aspergillus Genus

open access: yesMolecules, 2023
Alkaloids represent a large family of natural products with diverse structures and bioactivities. These compounds and their derivatives have been widely used in clinics to treat various diseases.
Juntai Zhu   +5 more
doaj   +1 more source

Six New Antimicrobial Metabolites from the Deep-Sea Sediment-Derived Fungus Aspergillus fumigatus SD-406

open access: yesMarine Drugs, 2021
Six new metabolites, including a pair of inseparable mixtures of secofumitremorgins A (1a) and B (1b), which differed in the configuration of the nitrogen atom, 29-hydroxyfumiquinazoline C (6), 10R-15-methylpseurotin A (7), 1,4,23-trihydroxy-hopane-22,30-
Li-Hong Yan   +4 more
doaj   +1 more source

Novel Alkaloids from Marine Actinobacteria: Discovery and Characterization

open access: yesMarine Drugs, 2021
The marine environment is an excellent resource for natural products with therapeutic potential. Its microbial inhabitants, often associated with other marine organisms, are specialized in the synthesis of bioactive secondary metabolites.
Anne-Sofie De Rop   +8 more
doaj   +1 more source

Potential inhibitors of coronavirus 3-chymotrypsin-like protease (3CLpro): an in silico screening of alkaloids and terpenoids from African medicinal plants

open access: yesJournal of Biomolecular Structure and Dynamics, 2020
The novel coronavirus disease 2019 (COVID-19) caused by SARS-COV-2 has raised myriad of global concerns. There is currently no FDA approved antiviral strategy to alleviate the disease burden.
G. Gyebi   +4 more
semanticscholar   +1 more source

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