Results 41 to 50 of about 184,232 (306)

Plant-Based Indole Alkaloids: A Comprehensive Overview from a Pharmacological Perspective

Molecules, 2021
Plant-based indole alkaloids are very rich in pharmacological activities, and the indole nucleus is considered to contribute greatly to these activities.
Faisal Omar, Abu Montakim Tareq, Ali M. Alqahtani, Kuldeep Dhama, Mohammed Abu Sayeed, Talha Bin Emran, Jesus Simal-Gandara   +6 more
doaj   +1 more source

Tropane alkaloids in food [PDF]

, 2010
A large number of wild and cultured plants produce secondary metabolites that are toxic to humans and animals. Through accidental or intentional mixing of these plants with normal food and feed the consumers of these products will be exposed to the ...
Adamse, P., Egmond, H.P., van
core  

The relationship of physico-chemical properties and structure to the differential antiplasmodial activity of the cinchona alkaloids. [PDF]

, 2003
BACKGROUND: The 8-amino and 9-hydroxy substituents of antimalarial cinchona alkaloids have the erythro orientation while their inactive 9-epimers are threo.
Meyer David J, Adagu Ipemida S, Adagu, Ipemida S, Warhurst David C, Sylvia Y Lee, Meyer, David J, David C Warhurst, Craig John C, David J Meyer, Warhurst, David C, Lee, Sylvia Y, Ipemida S Adagu, Craig, John C, John C Craig, Lee Sylvia Y   +14 more
core   +1 more source

Electrolyte Additive Strategies in Aqueous Zn‐Ion Batteries: Recent Advances and Prospects

Advanced Science, EarlyView.
This article provides a comprehensive overview of the current status and future development directions of AZIBs electrolyte additives in three aspects: stabilizing zinc anodes (uniform deposition, inhibition of dendritic crystals), protecting cathodes (structural stability, inhibition of dissolution), and enhancing electrolyte stability (wider ...
Yuanze Yu, Hongmin Liu, Long Fan, Huakun Liu, Shixue Dou, Guoxiu Wang, Nana Wang, Zhongchao Bai   +7 more
wiley   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source

The function of secondary metabolites in resisting stresses in horticultural plants

Fruit Research
Horticultural plants contain various secondary metabolites (SMs), including flavonoids, terpenoids, and alkaloids. These compounds play a critical role in plant growth, helping the plants adapt to different types of stress and providing numerous health ...
Han Tang, Qingjie Wang, Haifeng Xie, Weixing Li   +3 more
doaj   +1 more source

C. elegans-based screen identifies lysosome-damaging alkaloids that induce STAT3-dependent lysosomal cell death

Protein & Cell, 2018
Lysosomes are degradation and signaling centers within the cell, and their dysfunction impairs a wide variety of cellular processes. To understand the cellular effect of lysosome damage, we screened natural small-molecule compounds that induce lysosomal ...
Yang Li, Yu Zhang, Qiwen Gan, Meng Xu, Xiao Ding, Guihua Tang, Jingjing Liang, Kai Liu, Xuezhao Liu, Xin Wang, Lingli Guo, Zhiyang Gao, Xiaojiang Hao, Chonglin Yang   +13 more
doaj   +1 more source

Plants Secondary Metabolites as Blood Glucose-Lowering Molecules

Molecules, 2021
Recently, significant advances in modern medicine and therapeutic agents have been achieved. However, the search for effective antidiabetic drugs is continuous and challenging.
Mayadah Bashir Shehadeh, Ghadeer A. R. Y. Suaifan, Ala’ Mustafa Abu-Odeh   +2 more
doaj   +1 more source

Dutch survey pyrrolizidine alkaloids in animal forage [PDF]

, 2009
Pyrrolizidine alkaloids (PAs) are secondary plant metabolites produced by a number of plants from the Asteraceae (Compositae), Boriginaceae and Fabaceae (Leguminosae) families.
Jong, J., de, Oosterink, J.E., Beumer, B., Mulder, P.P.J.   +3 more
core  

A Multidimensional Engineering Strategy Reprograms Microglia via Targeted and Sustained‐Release Extracellular Vesicles for Spinal Cord Injury Repair

Advanced Science, EarlyView.
A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong, Minhao Liu, Mingming Zheng, Jizhou Jia, Ziyan Zhu, Guang Kong, Jie Liu, Juan Wang, Wenbo Li, Qingyuan Wang, Qian Zhu, Peiran Chan, Tao Qin, Jiayang Wu, Yongjie Zhang, Chunming Tang, Cong Li, Jin Fan   +17 more
wiley   +1 more source