Results 31 to 40 of about 184,232 (306)

Bioactive Natural Products of Marine Sponges from the Genus Hyrtios

Molecules, 2017
Marine sponges are known as a rich source for novel bioactive compounds with valuable pharmacological potential. One of the most predominant sponge genera is Hyrtios, reported to have various species such as Hyrtios erectus, Hyrtios reticulatus, Hyrtios ...
Nourhan Hisham Shady, Ebaa M. El-Hossary, Mostafa A. Fouad, Tobias A. M. Gulder, Mohamed Salah Kamel, Usama Ramadan Abdelmohsen   +5 more
doaj   +1 more source

Oxoisoaporphines and Aporphines: Versatile Molecules with Anticancer Effects

Molecules, 2019
Cancer is a disease that involves impaired genome stability with a high mortality index globally. Since its discovery, many have searched for effective treatment, assessing different molecules for their anticancer activity.
Esteban Rodríguez-Arce, Patricio Cancino, Manuel Arias-Calderón, Paul Silva-Matus, Marianela Saldías   +4 more
doaj   +1 more source

Alkaloids with Their Protective Effects Against Aβ_25-35-Induced PC-12 Cell Injury from the Tubers of Pinellia pedatisecta Schott

Molecules
Seven new alkaloids [1, (±)-2, (±)-3, 4, and 5] and one new natural product (6), along with eight known analogues, were isolated from the tubers of Pinellia pedatisecta Schott. Their structures were determined by a comprehensive analysis of spectroscopic
Xu Chen, Yangang Cao, Kaili Ye, Yanling Liu, Fangge Chi, Ying Niu, Di Lu, Bingxian Zhao, Lan Chen, Xiaoke Zheng, Weisheng Feng   +10 more
doaj   +1 more source

The Occurrence and Bioactivities of Amaryllidaceae Alkaloids from Plants: A Taxonomy-Guided Genera-Wide Review

Plants
The distribution of Amaryllidaceae alkaloids, with a focus on their chemodiversity, has been reported previously, but not at a genera-wide diversity level.
G. David Lin, Pinky Vishwakarma, Paul N. Smith, Rachel W. Li   +3 more
doaj   +1 more source

Current Knowledge and Perspectives of Pyrrolizidine Alkaloids in Pharmacological Applications: A Mini-Review

Molecules, 2021
Pyrrolizidine alkaloids (PAs) are a widespread group of secondary metabolites in plants. PAs are notorious for their acute hepatotoxicity, genotoxicity and neurological damage to humans and animals.
Xianqin Wei, Weibin Ruan, Klaas Vrieling
doaj   +1 more source

Strictosidine, the common precursor for monoterpenoid indole alkaloids with 3 α and 3 β configuration [PDF]

, 1978
Recently we reported that strictosidine (l> is the key intermediate in the formation of the three classes (ASDidOf3DeIm5, Iboga, Corynanthe) of monoterpenoid indole alkaloids In Catharanthus roseus and a variety of other plant species in cell culture ...
Martina Rueffer, Rüffer, Martina, Nagakura, Naotaka, Zenk, Meinhart H., Meinhart H. Zenk, Naotaka Nagakura   +5 more
core   +1 more source

Cardiotropic medicinal products of plant origin. Prospects for use in modern clinical practice

Research Results in Pharmacology
Introduction: The aim of the research was to study the current state of use and improvement of the prospects for the using cardiological medicinal products obtained on the basis of medicinal plant raw materials.
Nadezhda V. Nesterova, Natalia D. Bunyatyan, Irina A. Samylina, Vladimir A. Evteev   +3 more
doaj   +1 more source

Foliar nitrogen supply enhances the recovery of photosynthetic performance of cold-stressed coffee (Coffea arabica L.) seedlings

Photosynthetica, 2020
Cold-stressed leaves possess an elevated risk of photodamage due to an inefficient photosynthetic apparatus during winter conditions. Recovery of cold-stressed coffee seedlings treated with different concentrations of nitrogen applied as foliar urea ...
R. ACIDRI, Y. SAWAI, Y. SUGIMOTO, D. SASAGAWA, T. MASUNAGA, S. YAMAMOTO, E. NISHIHARA   +6 more
doaj   +1 more source

NMR Metabolomic Profiling of Differentiated SH-SY5Y Neuronal Cells: Amyloid-β Toxicity and Protective Effects of Galantamine and Lycorine

Cells
Alzheimer’s disease (AD) is a multifactorial neurodegenerative disorder characterized by metabolic dysregulation, oxidative stress, amyloid-β (Aβ) aggregation, metal dyshomeostasis, and mitochondrial dysfunction.
Arian Kola, Filippo Costanti, Jordan Kahfi, Abdul-Hamid Emwas, Mariusz Jaremko, Daniela Valensin   +5 more
doaj   +1 more source

Variations of Alkaloid Accumulation and Gene Transcription in Nicotiana tabacum

Biomolecules, 2018
To increase the understanding of alkaloid biosynthesis in Nicotiana tabacum during whole plant growth periods, variations of the contents of alkaloids and the transcription of key biosynthetic genes in fresh leaves were investigated in three varieties at
Bo Sun, Yu-Xiao Tian, Fen Zhang, Qing Chen, Yong Zhang, Ya Luo, Xiao-Rong Wang, Fu-Cheng Lin, Jun Yang, Hao-Ru Tang   +9 more
doaj   +1 more source