The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji+3 more
wiley +1 more source
IONIZATION POTENTIALS OF ALKYL FREE RADICALS AND n-ALKANES THROUGH C17H36 BY ENERGY-CALIBRATED MOLECULAR ORBITAL METHODS [PDF]
Charles E. Melton, Hubert W. Joy
openalex +1 more source
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley +1 more source
Origins of Oil, a Correction and Further Comment on the Brunnock1 Even C-Number Predominance in Certain Higher Alkanes of African Crudes, and on the Biogenesis of Nonacosane [PDF]
Robert Robinson
openalex +1 more source
Analysis of the regulation of undecaprenyl diphosphate dephosphorylation in Escherichia coli
BacA, PgpB, and YbjG phosphatases are involved in undecaprenyl phosphate (C55P) synthesis in Escherichia coli. We analyzed the lipid contents and the gene expression in the gene‐disruption strains. Undecaprenyl diphosphate (C55PP) level increased in the bacA, ybjG double‐disruption strain, but C55P levels were similar in all strains.
Tomotaka Jitsukawa+2 more
wiley +1 more source
On the relation between Zenkevich and Wiener indices of alkanes [PDF]
A relatively complicated relation was found to exist between the quantity U, recently introduced by Zenkevich (providing a measure of internal molecular energy), and the Wiener index W (measuring molecular surface area and intermolecular forces).
ZARKO BOSKOVIC+3 more
doaj
Heats of Combustion and Formation of the n-Alkane-alpha,omega-dithiols from Ethane through Pentane. [PDF]
Margret Månsson+5 more
openalex +1 more source
Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu+12 more
wiley +1 more source
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li+5 more
wiley +1 more source
Degradation of Hydrocarbons by Members of the Genus Candida II. Oxidation of n -Alkanes and 1-Alkenes by Candida lipolytica [PDF]
Michael J. Klug, A. J. Markovetz
openalex +1 more source