Results 41 to 50 of about 84,309 (136)

Diverse soil carbon dynamics expressed at the molecular level [PDF]

, 2017
The stability and potential vulnerability of soil organic matter (SOM) to global change remains incompletely understood due to the complex processes involved in its formation and turnover.
Angst, Angst, Baisden, Batjes, Berhe, Bull, Bush, C. I. Zell, C. P. McIntyre, Carvalhais, Cerli, Collister, Cooper, Dai, Davidson, Diefendorf, Doetterl, Doetterl, Doetterl, Drenzek, E. Graf Pannatier, Eglinton, Eglinton, Eglinton, Etzold, F. Hagedorn, Feng, Feng, Feng, Feng, Galy, Galy, Gong, Graf Pannatier, Graf Pannatier, Graf Pannatier, He, Hobbie, Huang, Ivy-Ochs, Jandl, Jansen, Kalbitz, Krull, Lutzow, Matsumoto, Meehl, Muhr, Murage, N. Haghipour, Paul, Petsch, Reiffarth, Rethemeyer, Rumpel, Saliot, Sanderman, Schaub, Schmidt, Schrumpf, Schrumpf, Schäfer, Simoneit, Six, Solly, Spinoni, T. I. Eglinton, T. S. van der Voort, Tao, Tipping, Torn, Voort, Walthert, Walthert, Wiesenberg, Wiesenberg, Wynn, Wynn, X. Feng, Zhang   +79 more
core   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Factors affecting the extent of branching in fischertropsch synthesis products with iron-based catalysts [PDF]

, 1989
Branched products are mainly formed during secondary isomerization reactions, and not in the main synthesis reaction itself. The extent of branching is a function of the catalyst formulation. High acidity and a low hydrogenation strength of the catalyst (
Snel, R.
core   +2 more sources

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Impact of Asian continental outflow on the concentrations of O3, CO, NMHCs and halocarbons on Jeju Island, South Korea during March 2005 [PDF]

, 2007
As part of ABC-EAREX2005 experiment, numerous trace gases were measured at Gosan on Jeju Island, South Korea in March 2005 to characterize the impact of recent outflow from the Asian continent and to inter-compare measurement techniques used by ...
Blake, DR, Ding, A, Nam, JC, Wang, T, Wong, HLA   +4 more
core   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

At what chain length do unbranched alkanes prefer folded conformations?

, 2014
Short unbranched alkanes are known to prefer linear conformations, while long unbranched alkanes are folded. It is not known with certainty at what chain length the linear conformation is no longer the global minimum.
Bartlett, Rodney, Byrd, Jason N., Montgomery Jr, John A   +2 more
core   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Experimental study of paraffin wax potential as a physical modelling material for local environment [PDF]

, 1997
An experimental study on paraffin wax was done to investigate its potential as modelling material and observing the effect of local environment thermal parameter.
M. Yusuf, Md. Afendi
core