Results 11 to 20 of about 6,174 (170)
Structural Analysis of the AlkB Family in Poultry [PDF]
AnimalsThe objective of this study was to identify the AlkB family genes in poultry using bioinformatics, and to explore their molecular characteristics, evolutionary relationships, and expression patterns to clarify their potential functions in poultry.
Yuling Niu +6 more
doaj +4 more sources
Structure and mechanism of the alkane-oxidizing enzyme AlkB
Nature Communications, 2023 Alkanes are the most energy-rich form of carbon and are widely dispersed in the environment. Their transformation by microbes represents a key step in the global carbon cycle.
Xue Guo +8 more
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Bioinformatic mapping of AlkB homology domains in viruses [PDF]
BMC Genomics, 2005 Background AlkB-like proteins are members of the 2-oxoglutarate- and Fe(II)-dependent oxygenase superfamily. In Escherichia coli the protein protects RNA and DNA against damage from methylating agents. 1-methyladenine and 3-methylcytosine are repaired by
Drabløs Finn, Bratlie Marit S
doaj +3 more sources
Novel AlkB dioxygenases--alternative models for in silico and in vivo studies.
PLoS ONE, 2012 BackgroundALKBH proteins, the homologs of Escherichia coli AlkB dioxygenase, constitute a direct, single-protein repair system, protecting cellular DNA and RNA against the cytotoxic and mutagenic activity of alkylating agents, chemicals significantly ...
Damian Mielecki +8 more
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ALKB-1-dependent tRNA methylation is required for efficient paternal mitochondrial elimination [PDF]
Nature CommunicationsMaternal mitochondrial inheritance is secured by mechanisms that exclude paternal mitochondrial DNA (mtDNA). While, epigenetic modifications are vital for spermatogenesis and embryo development, their roles in the paternal mitochondrial elimination (PME)
Zhenhuan Luo +12 more
doaj +2 more sources
Cloning and Expression of Pseudomonas aeruginosa AlkB Gene in E. coli
Journal of Pure and Applied Microbiology, 2020 Pre identified hydrocarbons degrading bacteria were used in this study, specific primer was conducted to amplification of AlkB gene, approximately 1206bp band size of this gene for Pseudomonas aeruginosa was detected and proofed by sequence and ...
Fadhil N. Al-Kanany, Rasha M. Othman
doaj +3 more sources
Genomic analysis of Acinetobacter baumannii DUEMBL6 reveals diesel bioremediation potential and biosafety concerns. [PDF]
PLoS ONEThis study investigates the bioremediation potential of bacterial isolates from diesel-contaminated soils in Dhaka, Bangladesh. A total of 34 morphologically distinct bacterial strains were isolated from hydrocarbon-polluted sites, with Acinetobacter ...
Nizam Uddin +8 more
doaj +2 more sources
Redirecting linear hydrocarbon metabolism toward polyhydroxyalkanoate biosynthesis [PDF]
Microbial Cell FactoriesThis study explores how Pseudomonas putida EM2-4 metabolizes linear alkanes after acquiring an integrative and conjugative element (ICE) encoding a novel alkane monooxygenase (AlkB).
Rocío Palacios-Ferrer +5 more
doaj +2 more sources
The Selectivity and Inhibition of AlkB [PDF]
Journal of Biological Chemistry, 2003 AlkB is one of four proteins involved in the adaptive response to DNA alkylation damage in Escherichia coli and is highly conserved from bacteria to humans. Recent analyses have verified the prediction that AlkB is a member of the Fe(II) and 2-oxoglutarate (2OG)-dependent oxygenase family of enzymes.
Welford, R +4 more
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Non-homologous functions of the AlkB homologs [PDF]
Journal of Molecular Cell Biology, 2015 The DNA repair enzyme AlkB was identified in E. coli more than three decades ago. Since then, nine mammalian homologs, all members of the superfamily of alpha-ketoglutarate and Fe(II)-dependent dioxygenases, have been identified (designated ALKBH1-8 and FTO). While E.
Rune, Ougland +3 more
openaire +2 more sources