A novel strategy for partial purification of alkane hydroxylase from P. chrysogenum SNP5 through reconstituting its native membrane into liposome [PDF]
Scientific ReportsIntegral proteins or enzymes are still challenging to purify into their native state because of their need for an amphipathic environment and cofactors.
Satyapriy Das, Sangeeta Negi
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ALKBH1: emerging biomarker and therapeutic target for cancer treatment [PDF]
Discover OncologyAs neoplastic cells proliferate, disseminate, and infiltrate, they undergo substantial alterations in their epigenetic configuration. Among the pivotal enzymes implicated in this phenomenon is the AlkB family of demethylases, notably AlkB homolog 1 ...
Ming Zhu Xiao +5 more
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The elite eating quality alleles Wxb and ALKb are regulated by OsDOF18 and coordinately improve head rice yield [PDF]
Plant Biotechnol JSummary Head rice yield (HRY) measures rice milling quality and determines final grain yield and commercial value. Here, we report that two major quantitative trait loci for milling quality in rice, qMq‐1 and qMq‐2, represent allelic variants of Waxy lv /
Maodi Zhu +18 more
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bioRxivBacteria on leaf surfaces encounter highly variable access to nutrients and water. This oligotrophic environment is partly due to the presence of cuticular waxes that render the leaf surface hydrophobic, reducing the leaching of nutrients and water loss ...
R. Schlechter +4 more
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Genome-wide identification and characterization of ALKB homolog gene family in wheat (Triticum aestivum L.) [PDF]
Front Plant SciPengkun Wang +6 more
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Genome-Wide Identification of the Soybean AlkB Homologue Gene Family and Functional Characterization of GmALKBH10Bs as RNA m6A Demethylases and Expression Patterns under Abiotic Stress [PDF]
Plants (Basel)Jie Zhao +8 more
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Structural and mutational analysis of Escherichia coli AlkB provides insight into substrate specificity and DNA damage searching. [PDF]
PLoS ONE, 2010 BACKGROUND: In Escherichia coli, cytotoxic DNA methyl lesions on the N1 position of purines and N3 position of pyrimidines are primarily repaired by the 2-oxoglutarate (2-OG) iron(II) dependent dioxygenase, AlkB.
Paul J Holland, Thomas Hollis
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The AlkB Homolog SlALKBH10B Negatively Affects Drought and Salt Tolerance in Solanum lycopersicum
International Journal of Molecular Sciences, 2023 ALKBH proteins, the homologs of Escherichia coli AlkB dioxygenase, constitute a single-protein repair system that safeguards cellular DNA and RNA against the harmful effects of alkylating agents.
Hui Shen +6 more
semanticscholar +1 more source
Role of RNA modifications in carcinogenesis and carcinogen damage response
Molecular Carcinogenesis, Volume 62, Issue 1, Page 24-37, January 2023., 2023 Abstract The field of epitranscriptomics encompasses the study of post‐transcriptional RNA modifications and their regulatory enzymes. Among the numerous RNA modifications, N6‐methyladenosine (m6A) has been identified as the most common internal modification of messenger RNA (mRNA).
Michelle Verghese +2 more
wiley +1 more source
Non-homologous functions of the AlkB homologs [PDF]
Journal of Molecular Cell Biology, 2015 The DNA repair enzyme AlkB was identified in E. coli more than three decades ago. Since then, nine mammalian homologs, all members of the superfamily of alpha-ketoglutarate and Fe(II)-dependent dioxygenases, have been identified (designated ALKBH1-8 and FTO). While E.
Rune Ougland +3 more
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