Results 41 to 50 of about 3,618 (129)

Discovery and Biosynthesis of Celluxanthenes, Antibacterial Arylpolyene Alkaloids From Diverse Cellulose‐Degrading Anaerobic Bacteria

open access: yesAngewandte Chemie, Volume 137, Issue 24, June 10, 2025.
The structure and biosynthetic origin of the enigmatic “yellow affinity substance” (YAS) from the anaerobe thermophile Clostridium thermocellum (now: Acetivibrio thermocellus) were elucidated. YAS is a complex of unusual antibacterial arylpolyene alkaloids (celluxanthenes) that are produced by various cellulolytic anaerobes.
Keishi Ishida   +9 more
wiley   +2 more sources

Opportunities When Chemistry Meets Biology in Catalysis and Synthesis

open access: yesTransformative Chemistry, Volume 1, Issue 1, December 2025.
Biosynthesis and chemical synthesis possess complementary strengths and limitations. Integrating these two systems across multiple levels offers opportunities for molecular synthesis to become highly efficient, precise, versatile, and scalable in the future, while also ensuring environmental compatibility and resource renewability.
Xiao Xiao   +5 more
wiley   +1 more source

Cobalamin‐Dependent Aryl Methyl Ether O‐Demethylases: Promising Enzymes for Biocatalytic Applications from Lignin Valorization to Organic Synthesis

open access: yesChemCatChem, Volume 17, Issue 21, November 10, 2025.
Cobalamin‐dependent aryl methyl ether O‐demethylases have high potential for biocatalytic applications, including lignin valorization and synthetic chemistry. In this review, we provide a detailed overview of such O‐demethylase systems identified to date from various microorganisms, including their mechanism, substrate scope and selectivity, and ...
Niels Krabbe Johnsen   +4 more
wiley   +1 more source

Interactions between piperonyl butoxide analogues and metabolic enzymes conferring insecticide resistance

open access: yes, 2010
The insecticide synergist, piperonyl butoxide (PBO), has been used to reduce resistance factors and to characterise metabolic resistance resulting from mixed function oxidases (MFOs).
Philippou, Despina, Philippou, Despina
core   +1 more source

Origin and characterization of cyclodepsipeptides: Comprehensive structural approaches with focus on mass spectrometry analysis of alkali‐cationized molecular species

open access: yesMass Spectrometry Reviews, Volume 44, Issue 6, Page 1013-1098, November/December 2025.
Abstract Cyclodepsipeptides (CDPs) represent a huge family of chemically and structurally diverse molecules with a wide ability for molecular interactions. CDPs are cyclic peptide‐related natural products made up of both proteinogenic and nonproteinogenic amino acids linked by amide and ester bonds.
Sophie Liuu   +10 more
wiley   +1 more source

Targeting antibiotic resistance [PDF]

open access: yes, 2016
Finding strategies against the development of antibiotic resistance is a major global challenge for the life sciences community and for public health.
Chellat, Mathieu F.   +2 more
core   +1 more source

Repetitive and Non-Repetitive DNA Sequences and a Speculation on the Origins of Evolutionary Novelty [PDF]

open access: yes, 1971
Recent experimental information on DNA sequence repetition is reviewed, and the significance of both repetitive and non-repetitive sequence considered.
Britten, Roy J., Davidson, Eric H.
core   +1 more source

Application of Enzymes in Regioselective and Stereoselective Organic Reactions [PDF]

open access: yes, 2020
Nowadays, biocatalysts have received much more attention in chemistry regarding their potential to enable high efficiency, high yield, and eco-friendly processes for a myriad of applications.
Duke, Colbee N.   +7 more
core   +2 more sources

Engineering Alloxazines by Boron Coordination and Click Chemistry toward Small‐molecule Fluorescent Probes

open access: yesChemistry – A European Journal, Volume 31, Issue 47, August 21, 2025.
The design of fluorescent molecules inspired by natural cofactors to monitor biological processes carries some intrinsic advantages. This is particularly relevant in the case of redox cofactors with innate fluorescence properties, such as flavins, and synthetic strategies toward their functionalized analogues are of high interest to modulate properties.
Oscar Charpentier   +5 more
wiley   +1 more source

An Update: Enzymatic Synthesis for Industrial Applications

open access: yesAngewandte Chemie International Edition, Volume 64, Issue 27, July 1, 2025.
Biocatalysis has become a sustainable and cost‐competitive alternative to established chemical synthesis, enabling the enzyme‐based production of not only commodity chemicals but (non‐natural) amino acids, (rare) sugars, as well as synthetic nucleotides.
Thomas Bayer   +4 more
wiley   +1 more source

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