Results 91 to 100 of about 3,196,403 (286)
Privileged Chiral Photocatalysts
Angewandte Chemie, EarlyView.Privileged chiral catalysts have transformed asymmetric synthesis, conferring generality to processes that are routinely leveraged in the construction of societally important functional small molecules. This mini‐review is intended to survey the conception and evolution of privileged chiral photocatalyst scaffolds that enable simultaneous orchestration
Emanuel Studer +3 more
wiley +2 more sources
Química Nova, 2005 The chemotherapy agents against cancer may be classified as "cell cycle-specific" or "cell cycle-nonspecific". Nevertheless, several of them have their biological activity related to any kind of action on DNA such as: antimetabolic agents (DNA synthesis ...
Vera Lúcia de Almeida +5 more
doaj +1 more source
Engineered Hydrogels Revolutionize Locoregional Cancer Immunotherapy
Advanced NanoBiomed Research, EarlyView.This review systematically summarizes the latest research progress on injectable hydrogels in cancer immunotherapy, highlighting their unique advantages in precise immune activation, local drug‐controlled release, and immune microenvironment remodeling. These features provide innovative solutions to overcome the bottlenecks of systemic side effects and
Jiyong Wei +3 more
wiley +1 more source
Alkylating agents in membranous nephropathy: efficacy proven beyond doubt.
Nephrology, Dialysis and Transplantation, 2010 Idiopathic membranous nephropathy (iMN) is one of the most common causes of the nephrotic syndrome in adults. The clinical course of patients with iMN is quite variable.
J. Hofstra, J. Wetzels
semanticscholar +1 more source
Nanoparticles Functionalized with Polymer Brushes for Gene Delivery
Advanced NanoBiomed Research, EarlyView.The engineering of the next generation gene delivery vectors requires the precise control of the architecture and physicochemical interactions controlling the transport, targeting, uptake, and release of nucleic acid materials to targeted cells. Polymer brush‐functionalized nanomaterials offer unprecedented control over such design and properties, and ...
Carlos E. Neri‐Cruz, Julien E. Gautrot
wiley +1 more source
Cytotoxicity of alkylating agents towards sensitive and resistant strains of Escherichia coli in relation to extent and mode of alkylation of cellular macromolecules and repair of alkylation lesions in deoxyribonucleic acids [PDF]
, 1968 P.D. Lawley, P. Brookes
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Bio-Protocol, 2015 The topology of membrane proteins and enzymes can be determined using various methods including reporter protein fusions and accessibility of cysteine residues to alkylating agents.
Sébastien Gélis-Jeanvoine +1 more
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DIFFERENTIAL SENSITIVITY OF MOUSE SPERMATOGENESIS TO ALKYLATING AGENTS [PDF]
, 1961 J. Moutschen
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Temozolomide-Induced Myelodysplasia
Advances in Hematology, 2010 A patient who had received temozolomide (TMZ) as a single agent in treatment of malignant glioma developed therapy-induced myelodysplasia (T-MDS). TMZ is an orally active imidazotetrazine which methylates guanine residues in DNA, ultimately causing ...
Ethan A. Natelson, David Pyatt
doaj +1 more source
Enzyme-alterable alkylating agents. I. Synthesis, chemical properties, and toxicities of sulfur mustards containing enzyme-susceptible amide bonds [PDF]
, 1962 Benjamin Witten +10 more
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