Results 141 to 150 of about 3,196,403 (286)

The role of bendamustine in the treatment of indolent non-Hodgkin lymphoma

open access: yesCancer Management and Research, 2009
Ibrahim T Aldoss1, Susan M Blumel2, Philip J Bierman21Department of Internal Medicine, Creighton University Medical Center, Omaha, NE, USA; 2Section of Hematology – Oncology, Department of Internal Medicine, University of Nebraska Medical ...
Ibrahim T Aldoss   +2 more
doaj  

O6-Methylguanine DNA Methyltransferase Status Does Not Predict Response or Resistance to Alkylating Agents in Well-Differentiated Pancreatic Neuroendocrine Tumors.

open access: yesPancreas, 2017
N. Raj   +9 more
semanticscholar   +1 more source

In Situ Generation of Alkyl–λ3–Iodanes as Soft and Highly Reactive Electrophiles

open access: yesChemistryEurope, EarlyView.
A convenient and practical method for the clean generation of alkyl–λ3–iodanes is reported using tetraalkylsilanes and iodine tris(trifluoroacetate). An in situ‐generated methyl–λ3–iodane works as a soft and highly electrophilic methylation reagent, which enables methylation of tertiary sulfonamides at low temperatures and following transamidation and ...
Rina Katsuta   +6 more
wiley   +1 more source

Letter: Myeloma cells after treatment with alkylating agents [PDF]

open access: bronze, 1975
Michele Baccarani   +1 more
openalex   +1 more source

Advances in Enaminomaleimides Chemistry: Synthesis, Chemical Applications, and Perspectives

open access: yesChemistryEurope, EarlyView.
Enaminomaleimides are versatile building blocks for the construction of functionalized heterocycles. Their unique nucleophilic character, contrasting with the classical electrophilic nature of maleimides, enables diverse synthetic applications, showing promising potential in both materials science and medicinal chemistry.
Adrián López‐Francés   +5 more
wiley   +1 more source

Novel Synthesis of the Antifungal Cyclic Lipopeptide Iturin A and Its Fluorinated Analog for Structure‐Activity Relationship Studies

open access: yesChemistry – A European Journal, EarlyView.
Iturin A is an antifungal lipopeptide with a wide range of applications. In this study, we present a novel synthesis of iturin A via enantiomeric synthesis of the β‐amino fatty acid and on‐resin cyclization. We also obtained the (S)‐epimer of iturin A, showing a dramatic loss of bioactivity, and a monofluorinated analog, which retained the bioactivity ...
Periklis Karamanis   +6 more
wiley   +1 more source

The Evolving Role of Alkylating Agents in Multiple Myeloma: From the Past and Present to Next-Generation Peptide Drug Conjugates

open access: yeshealthbook TIMES. Oncology Hematology
Despite significant recent advances in treatment with small molecules, inhibitor, antibodies and immunotherapy, multiple myeloma (MM) remains an incurable malignancy characterized by high rates of relapse. Alkylating agents, a cornerstone of MM treatment,
Yuxin Liu   +11 more
doaj   +1 more source

Recent Advances in Detergent Chemistry and Handling Support Membrane Protein Analysis Including Lipid Interactions

open access: yesChemistry – A European Journal, EarlyView.
Detergent design parameters determine experimental successes in membrane protein research. Recent progresses in detergent chemistry are reviewed to promote the top‐down design of non‐ionic detergents for the purification and analysis of intact membrane proteins, including lipid interactions.
Katharina Alker   +2 more
wiley   +1 more source

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