Results 141 to 150 of about 3,196,403 (286)
The role of bendamustine in the treatment of indolent non-Hodgkin lymphoma
Ibrahim T Aldoss1, Susan M Blumel2, Philip J Bierman21Department of Internal Medicine, Creighton University Medical Center, Omaha, NE, USA; 2Section of Hematology – Oncology, Department of Internal Medicine, University of Nebraska Medical ...
Ibrahim T Aldoss+2 more
doaj
Expansion of the growth fraction in multiple myeloma with alkylating agents [PDF]
SE Salmon
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In Situ Generation of Alkyl–λ3–Iodanes as Soft and Highly Reactive Electrophiles
A convenient and practical method for the clean generation of alkyl–λ3–iodanes is reported using tetraalkylsilanes and iodine tris(trifluoroacetate). An in situ‐generated methyl–λ3–iodane works as a soft and highly electrophilic methylation reagent, which enables methylation of tertiary sulfonamides at low temperatures and following transamidation and ...
Rina Katsuta+6 more
wiley +1 more source
Letter: Myeloma cells after treatment with alkylating agents [PDF]
Michele Baccarani+1 more
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Advances in Enaminomaleimides Chemistry: Synthesis, Chemical Applications, and Perspectives
Enaminomaleimides are versatile building blocks for the construction of functionalized heterocycles. Their unique nucleophilic character, contrasting with the classical electrophilic nature of maleimides, enables diverse synthetic applications, showing promising potential in both materials science and medicinal chemistry.
Adrián López‐Francés+5 more
wiley +1 more source
Reduction of the toxicity and mutagenicity of alkylating agents in mammalian cells harboring the Escherichia coli alkyltransferase gene. [PDF]
John Brennand, GP Margison
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Iturin A is an antifungal lipopeptide with a wide range of applications. In this study, we present a novel synthesis of iturin A via enantiomeric synthesis of the β‐amino fatty acid and on‐resin cyclization. We also obtained the (S)‐epimer of iturin A, showing a dramatic loss of bioactivity, and a monofluorinated analog, which retained the bioactivity ...
Periklis Karamanis+6 more
wiley +1 more source
Despite significant recent advances in treatment with small molecules, inhibitor, antibodies and immunotherapy, multiple myeloma (MM) remains an incurable malignancy characterized by high rates of relapse. Alkylating agents, a cornerstone of MM treatment,
Yuxin Liu+11 more
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Detergent design parameters determine experimental successes in membrane protein research. Recent progresses in detergent chemistry are reviewed to promote the top‐down design of non‐ionic detergents for the purification and analysis of intact membrane proteins, including lipid interactions.
Katharina Alker+2 more
wiley +1 more source