Results 131 to 140 of about 81,731 (287)

Life-Cycle-Dependent Toxicities of Mono- and Bifunctional Alkylating Agents in the 3R-Compliant Model Organism C. elegans. [PDF]

Cells, 2023
Ruszkiewicz J, Endig L, Güver E, Bürkle A, Mangerich A.   +4 more
europepmc   +1 more source

Detection of the GH Analogue Redalsomatropin Alfa in Sports Drug Testing: Immunological Approaches and LC‐HRMS/MS

Drug Testing and Analysis, EarlyView.
After evaluating the compatibility of the GH analogue redalsomatropin alfa with approved doping control immunoassays for rhGH, it was implemented into the existing detection method for somatrogon employing affinity purification with GHR‐Fc‐conjugated magnetic beads, tryptic digestion, and LC‐HRMS/MS to allow for a specific and sensitive detection ...
Katja Walpurgis, Andreas Thomas, Jasmin Thelen, Bettina Majer, Maneera Al‐Jaber, Wadha Abushareeda, Mario Thevis   +6 more
wiley   +1 more source

Alcohols as Alkylating Agents in the Cation-Induced Formation of Nitrogen Heterocycles. [PDF]

Angew Chem Int Ed Engl, 2022
Cox L, Zhu Y, Smith PJ, Christensen KE, Sidera Portela M, Donohoe TJ.   +5 more
europepmc   +1 more source

Significance of tagl and mfd genes in the virulence of non-typeable Haemophilus infl uenzae [PDF]

, 2015
Non-typeable Haemophilus infl uenzae (NTHi) is an opportunist pathogen well adapted to the human upper respiratory tract and responsible for many respiratory diseases.
David Moranta, Denis A. Spricig, Jordi Barbé, José Antonio Bengoechea, Montserrat Llagostera, Pilar Cortés   +5 more
core   +1 more source

Design and Synthesis of Lactose‐Derived Ligands and Their Application in Asymmetric Friedel–Crafts Alkylation

European Journal of Organic Chemistry, EarlyView.
This work describes the synthesis of lactose‐ and glucose‐derived chiral ligands and their application in the catalytic enantioselective Friedel–Crafts alkylation of indole with a series of trans‐β‐nitrostyrenes. The optimal ligand was an acetate protected, lactose‐derived pyridyl imine and its zinc complex afforded ees up to 93% and yields up to 93 ...
Sandra Bulawa, Julia Bruno‐Colmenarez, Patrick J. Guiry   +2 more
wiley   +1 more source

Loss of p16 does not protect against premature ovarian insufficiency caused by alkylating agents. [PDF]

BMC Pregnancy Childbirth, 2023
Liu F, Wan Q, Liu P, Miao D, Dai X, Chen L.   +5 more
europepmc   +1 more source

A Direct Method to Prepare Zwitterionic Organotrifluoroborates: Ammonium and Sulfonium Derivatives

European Journal of Organic Chemistry, EarlyView.
Organotrifluoroborates find applications in synthesis, diagnostics, and theranostics. This study outlines a one‐step reaction for producing ammonium and sulfonium trifluoroborate zwitterion derivatives. This method achieves satisfactory yields without the need for expensive reagents.
Vanessa Re, Antonio Lucchini, Diego Caprioglio, Alberto Minassi, Zhenwei Yuan, Daniela Imperio, Luigi Panza   +6 more
wiley   +1 more source

Alcohols as Alkylating Agents: Photoredox-Catalyzed Conjugate Alkylation via In Situ Deoxygenation. [PDF]

Angew Chem Int Ed Engl, 2022
Wang JZ, Sakai HA, MacMillan DWC.
europepmc   +1 more source

Chemical Syntheses of 3′ and 5′ Phosphorylated Oligonucleotides: An Overview

European Journal of Organic Chemistry, EarlyView.
This review provides an overview of the various chemical methods employed in the synthesis of oligonucleotides bearing a phosphate group at their 3′ or 5′ end. Notably, it presents modified phosphoramidites and supports developed for this purpose. Oligonucleotides (ON) with a phosphate monoester group at their 3′ or 5′ end have applications in many ...
Rémy Lartia
wiley   +1 more source

Commonly Used Alkylating Agents Limit Persulfide Detection by Converting Protein Persulfides into Thioethers. [PDF]

Angew Chem Int Ed Engl, 2022
Schilling D, Barayeu U, Steimbach RR, Talwar D, Miller AK, Dick TP.   +5 more
europepmc   +1 more source