Results 141 to 150 of about 1,549,035 (266)
No relationship between hepatitis C infection and risk of myeloid malignancy
Haematologica, 2005 The etiology of myeloid malignancies is related to chromosomal damage caused by irradiation, alkylating agents, viral infection and so forth; however, few clinical studies have been published on the association between viral infection and the development
N Murashige +4 more
doaj
Self-Immolative System for Disclosure of Reactive Electrophilic Alkylating Agents: Understanding the Role of the Reporter Group. [PDF]
J Org Chem, 2021 Gavriel AG +7 more
europepmc +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum +5 more
wiley +1 more source
Developmental toxicity of alkylating agents in differentiating cell cultures
, 1996 Thesis (Ph. D.)--University of Washington, 1996Alkylating agents are well known carcinogens and teratogens. Highest exposures occur in occupational settings, although other lifestyle factors also contribute to exposure. The four alkylating agents used in
Seeley, Marguerite R
core
Biotechnology and Bioengineering, EarlyView.ABSTRACT The agitation power input substantially impacts the oxygen transfer rate in aerobic fermentation processes. Furthermore, in a carbon‐limited process where the substrate feed rate is controlled by the concentration of dissolved oxygen, the power input will consequently govern the feed rate.
Mariana Albino +6 more
wiley +1 more source
Induction and Enhancement of Bacteriocin Production (Review)
Biotechnology and Bioengineering, EarlyView.ABSTRACT Conventionally, bacteriocins are produced by microorganisms on complex substrates, released as semi‐purified preparations or crude fermentates. These bacteriocin‐containing products often exhibit unsatisfactory purity, low active‐substance content, and high production costs, limiting their commercialization and use. This review aims to analyze
Oksana Knysh, Artur Martynov
wiley +1 more source
Carbon Energy, EarlyView.The present review discusses the advancement in the catalytic synthesis of 5‐alkoxymethylfurfural (AMF) and levulinate esters (LEs) from the aspects of catalytic systems, reaction mechanisms, product isolation, and techno‐economic analysis, supplying valuable insights toward future sustainable and efficient manufacture of AMF and LEs. ABSTRACT The huge
Jun Zhang +6 more
wiley +1 more source
Repurposing Alkylating Agents in Melanoma via ERCC8 Silencing: A Novel Therapeutic Strategy. [PDF]
Cancers (Basel)Filippi S +5 more
europepmc +1 more source
Genomic Adaption and Mutational Patterns in a HaCaT Subline Resistant to Alkylating Agents and Ionizing Radiation. [PDF]
Int J Mol Sci, 2021 Ullmann R +11 more
europepmc +1 more source
Organelle‐Resolved Tetrazine‐trans‐Cyclooctene Click Chemistry for Cargo Delivery and Release
Chemistry – A European Journal, EarlyView.Bioorthogonal click chemistry tools provide a means for specific intracellular conjugation of molecules. In this study, we used reactive tetrazine (Tz) and TCO moieties for labeling of organelles and organelle‐specific delivery and activation of doxorubicin prodrugs.
Oleh Durydivka +6 more
wiley +1 more source