Results 161 to 170 of about 86,457 (338)

Increased Sensitivity of Transforming Growth Factor (TGF) β1 Null Cells to Alkylating Agents Reveals a Novel Link between TGFβ Signaling and O 6-Methylguanine Methyltransferase Promoter Hypermethylation [PDF]

, 2001
Hisaharu Yamada, Kinnimulki Vijayachandra, C. Gail Penner, Adam B. Glick   +3 more
openalex   +1 more source

Mechanism and Origin of Remote Stereocontrol in the Organocatalytic Enantioselective Formal C(sp²)-H Alkylation Using Nitroalkanes as Alkylating Agents. [PDF]

J Am Chem Soc, 2022
Chandra Mallojjala S, Sarkar R, Karugu RW, Manna MS, Ray S, Mukherjee S, Hirschi JS.   +6 more
europepmc   +1 more source

Late‐Stage Phenylation From [13C6] and [2H5]Benzene: A Versatile Tool for Stable Isotope Labeled MS Standards

Chemistry – A European Journal, EarlyView.
ABSTRACT We explored aryl thianthrenation as a tool for directly incorporating multiple isotopes into molecular scaffolds starting from full isotopically labeled benzene. Stable isotope‐labeled (SIL) molecules are indispensable tools for investigating chemical and biological mechanisms and quantifying metabolites.
Alexandre Labiche, Bouchaib Mouhsine, Dorian Dupommier, Louise Fogel, Frédéric Robert, David‐Alexandre Buisson, Frédéric Taran, Davide Audisio   +7 more
wiley   +1 more source

Assessment of Drug Utilization Pattern of Chemotherapeutic Agents and its Cost Analysis in a Day Care Unit of a Tertiary Care Hospital: An Observational Study

Journal of Nobel Medical College
Background: Cancer remains a leading cause of mortality worldwide, with increasing incidence and significant treatment costs, particularly in developing countries like Nepal.
Rekha Shah, Prem Kumar Mandal, Anjali Mishra, Rajesh Yadav, Nabin Kumar Yadav   +4 more
doaj   +1 more source

Photoactivatable V-Shaped Bifunctional Quinone Methide Precursors as a New Class of Selective G-quadruplex Alkylating Agents. [PDF]

Chemistry, 2022
Lena A, Benassi A, Stasi M, Saint-Pierre C, Freccero M, Gasparutto D, Bombard S, Doria F, Verga D.   +8 more
europepmc   +1 more source

Supercritical water deasphalting and desulphurization of heavy fuel oil with comprehensive molecular‐level analysis and techno‐economic analysis

The Canadian Journal of Chemical Engineering, EarlyView.
Supercritical water deasphalting. Abstract The removal of sulphur from heavy fuel oil (HFO) is essential to address environmental concerns and comply with the stringent regulations imposed by the International Maritime Organization (IMO) in 2020. Previously, the acceptable limit for sulphur was 3.5 wt.%, but it was recently changed to 0.5 wt.%.
Biswajit Saha, Sundaramurthy Vedachalam, Nathalie Baquerizo, Ajay K. Dalai, Aiping Chen, Saumitra Saxena, Bassam Dally   +6 more
wiley   +1 more source

ABT199/venetoclax potentiates the cytotoxicity of alkylating agents and fludarabine in acute myeloid leukemia cells. [PDF]

Oncotarget, 2022
Valdez BC, Murray D, Yuan B, Nieto Y, Popat U, Andersson BS.   +5 more
europepmc   +1 more source

Investigating the Ligand‐Binding Properties of N‐arylbenzimidazoles as Novel Elastase Inhibitors

ChemMedChem, EarlyView.
A series of novel N‐[(3,5‐dimethylphenyl)methyl]‐1H‐benzimidazole derivatives is designed, synthesized, and evaluated for inhibitory activity against elastase. Several compounds demonstrate an antielastase activity, including the N‐(2‐bromophenyl)‐2‐(6‐chloro‐1‐(3,5‐dimethylbenzyl)‐1H‐benzo[d]imidazol‐2‐ylthio)acetamide, showing the greatest potency ...
Giovanna Pitasi, Sonia Floris, Francesca Mancuso, Giulia Savoca, Rosaria Gitto, Antonella Fais, Laura De Luca   +6 more
wiley   +1 more source

PML expression in soft tissue sarcoma: Prognostic and predictive value in alkylating agents/antracycline‐based first line therapy

, 2011
Bruno Vincenzi, Daniele Santini, Gaia Schiavon, Anna Maria Frezza, Marianna Silletta, Pierfilippo Crucitti, Paolo G. Casali, Angelo Paolo Dei Tos, Sabrina Rossi, Sérgio Rizzo, Giuseppe Badalamenti, Rosa Maria Tomasino, Antonio Russo, James E. Butrynski, Giuseppe Tonini   +14 more
openalex   +2 more sources

[Retracted] The Fanconi anemia pathway sensitizes to DNA alkylating agents by inducing JNK‑p53‑dependent mitochondrial apoptosis in breast cancer cells. [PDF]

Int J Oncol, 2022
Zhao L, Li Y, He M, Song Z, Lin S, Yu Z, Bai X, Wang E, Wei M.   +8 more
europepmc   +1 more source