Results 161 to 170 of about 3,196,403 (286)
Patients with tuberous sclerosis have fibroblasts with normal limits for growth characteristics and sensitivities to DNA alkylating agents [PDF]
, 1984 Kousaku Ohno, Kenzo Takeshita
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European Journal of Inorganic Chemistry, EarlyView.A series of new air‐stable ruthenium(II) bis‐triphenylphosphine complexes comprising substituted pyridine–quinoline ligands have been developed via a one‐pot procedure. The new complexes successfully serve as scaffolds to promote catalytic CC bond formation, more precisely the α‐alkylation of ketones with primary alcohols, via the borrowing hydrogen ...
Nikolaos Zacharopoulos +6 more
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ON THE MUTAGENIC EFFECT OF ALKYLATING AGENTS [PDF]
Proceedings of the National Academy of Sciences, 1960 Ekkehard Bautz, Ernst Freese
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Hydrogen peroxide ‐ responsive aminoferrocene prodrugs
European Journal of Organic Chemistry, Accepted Article.Aminoferrocene (AF)‐based prodrugs are activated in cancer cells through reactions with H₂O₂ and other reactive oxygen species (ROS), generating electron‐rich AF’s. These, in turn, induce the production of highly toxic O2·‐ and HO·, leading to cancer cell death.
Marlies Körber +3 more
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Balancing repair and tolerance of DNA damage caused by alkylating agents
Nature Reviews. Cancer, 2012 Dragony Fu, J. Calvo, L. Samson
semanticscholar +1 more source
Toward the Synthesis of 3,3‐Difluoro Deaminated Sialic Acid (C3DFKDN)
European Journal of Organic Chemistry, EarlyView.The synthesis of protected C3‐difluoro KDN (C3DFKDN), an unnatural derivative of the sialic acid member, KDN, and key building block for KDN‐based chemical probes, is reported. Its 12‐step synthetic route starts from commercially available methyl d‐mannopyranoside and key steps include a Reformatsky reaction with ethyl bromodifluoroacetate, alkylation ...
Lemeng Chao, Tom Wennekes
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Enzyme activated alkylating agents [PDF]
British Journal of Cancer, 1973 C R Ball, J A Double, J Goodban
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