Results 171 to 180 of about 80,529 (226)

Fucosylation limits ADCC in clinically used anti‐RhD monoclonal antibodies

Transfusion, EarlyView.
Abstract Background Haemolytic disease of the fetus and newborn (HDFN) is caused by maternal alloantibodies, often targeting the D antigen on fetal red blood cells. Maternal immunization is preventable with timely administration of anti‐D polyclonal antibodies (pAbs).
Gabriela Koike, Albert Bondt, Douwe Schulte, Rien Leuvenink, Dirk Jan Mons, Peter C. Ligthart, E. Joanne T. Verweij, AFRICARhE Consortium, Enrico Lopriore, E. J. T. Joanne Verweij, Tienke Vermeiden, Thomas van den Akker, C. Ellen van der Schoot, Derek P. de Winter, Renske van Oever, Abera Kenay Tura, Tadesse Gure, Assefa Desalew, Tewodros Tesfa, Konjit Eshetu, Jeremia Pyuza, Rafiki N. Mjema, Priscus John Mapendo, Jeremiah John Hhera, Bariki Mchome, Patricia Swai, Blandina T. Mmbaga, Aisa Shayo, Peter Moons, Kondwani Kawaza, Luis Gadama, Albert J. R. Heck, C. Ellen van der Schoot, Gestur Vidarsson   +33 more
wiley   +1 more source

Beyond Alkylating Agents for Gliomas: Quo Vadimus? [PDF]

Am Soc Clin Oncol Educ Book, 2017
Puduvalli VK, Chaudhary R, McClugage SG, Markert J.   +3 more
europepmc   +1 more source

A Scalable and Resource‐Saving Synthesis of Dipyrromethanes and Tetrapyrroles via Geminal Diethers: Minimal Polymer Formation and Facile Purification

Advanced Synthesis &Catalysis, Volume 368, Issue 7, 1 April 2026.
Geminal dimethoxyethers react with pyrrolic nucleophiles in an efficient and clean reaction under anhydrous, mild conditions, which contrasts with the reactivity of the respective carbonyl compounds. Polymerization is effectively inhibited, providing access to dipyrromethanes, porphyrins, and calix[4]pyrroles that are easily purified.
Janos Wasternack, Clara Schritt, Luca Steiner, Ole Specht, Friedrich Braune, Marius Balizs, Sebastian Müller, Anja Wiesner, Beate Paulus, Siegfried Eigler, Christoph A. Schalley   +10 more
wiley   +1 more source

Exploring Affordable Curative Therapy for Sickle Cell Disease in Africa: A Comprehensive Overview

American Journal of Hematology, Volume 101, Issue S1, Page 56-74, April 2026.
ABSTRACT The practical aspects of developing curative treatments for sickle cell disease (SCD) in Africa, such as gene therapy and hematopoietic stem cell transplantation, involve strengthening healthcare infrastructure, training healthcare professionals, establishing regional treatment centers, and creating national SCD programs.
Adetola A. Kassim, Alexis A. Thompson, Punam Malik   +2 more
wiley   +1 more source

Persistence of DNA adducts, hypermutation and acquisition of cellular resistance to alkylating agents in glioblastoma. [PDF]

Cancer Biol Ther, 2017
Head RJ, Fay MF, Cosgrove L, Y C Fung K, Rundle-Thiele D, Martin JH.   +5 more
europepmc   +1 more source

Antineoplastic Alkylating Agent [PDF]

, 2020
openaire   +1 more source

Supercritical water deasphalting and desulphurization of heavy fuel oil with comprehensive molecular‐level analysis and techno‐economic analysis

The Canadian Journal of Chemical Engineering, Volume 104, Issue 4, Page 1727-1742, April 2026.
Supercritical water deasphalting. Abstract The removal of sulphur from heavy fuel oil (HFO) is essential to address environmental concerns and comply with the stringent regulations imposed by the International Maritime Organization (IMO) in 2020. Previously, the acceptable limit for sulphur was 3.5 wt.%, but it was recently changed to 0.5 wt.%.
Biswajit Saha, Sundaramurthy Vedachalam, Nathalie Baquerizo, Ajay K. Dalai, Aiping Chen, Saumitra Saxena, Bassam Dally   +6 more
wiley   +1 more source

Hypoxia-Activated Alkylating Agents in BRCA1-Mutant Ovarian Serous Carcinoma. [PDF]

Cureus, 2017
Conroy M, Borad MJ, Bryce AH.
europepmc   +1 more source

I. Alkylating agents [PDF]

Acta Radiologica, 1971
openaire   +1 more source

Optimizing Body Size‐Based Dosing Approaches for Antibody–Drug Conjugates

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 872-880, April 2026.
Optimized dosing precision of antibody–drug conjugates (ADCs) remains challenging due to narrow therapeutic indices, efficacious doses near the maximum tolerated dose, and substantial interindividual variability in exposure. Body size‐based dosing can reduce exposure variability when the allometric scaling exponent for clearance α = 1 but may over‐ or ...
Andrew B. SyBing, Diane D. Wang
wiley   +1 more source