Results 31 to 40 of about 3,238,601 (165)
Computational Investigations of Selected Enzymes From Two Iron and α-ketoglutarate-Dependent Families [PDF]
, 2021 DNA alkylation is used as the key epigenetic mark in eukaryotes, however, most alkylation in DNA can result in deleterious effects. Therefore, this process needs to be tightly regulated. AlkB and TET are families within the Fe and $\alpha$-kg-dependent superfamily of enzymes that are tasked with dealkylating DNA and RNA in cells.
arxiv +1 more source
Multifunctional photoresponsive organic molecule for electric field sensing and modulation [PDF]
arXiv, 2021 Organic molecules with nonlinear optical behavior have advanced a wide range of fields spanning from integrated photonics to biological imaging. With advances in microscopy, an emerging application is multifunctional nonlinear organic imaging agents.
arxiv
Effect of alkyl substituents on the adsorption of thienylenevinylene oligomers on the Si (100) surface [PDF]
Surface Science 473, 1-2 (2001) 1-7, 2012 The adsorption of thienylenevinylene oligomers on the Si(100) surface has been investigated using scanning tunneling microscopy. The mode of substitution of the thiophene ring exerts a strong influence on the adsorption configurations and the images of the oligomer based on 3,4-dihexyl thiophene are highly voltage dependent. We discuss the influence of
arxiv +1 more source
Surface Dipoles and Work Functions of Alkylthiolates and Fluorinated Alkylthiolates on Au(111) [PDF]
J. Phys. Chem. B 2006, 110, 22628-22634, 2006 We study the dipole formation at the surface formed by -CH3 and -CF3 terminated shortchain alkyl-thiolate monolayers on Au(111). In particular, we monitor the change in work function upon chemisorption using density functional theory calculations. We separate the surface dipole into two contributions, resulting from the gold-adsorbate interaction and ...
arxiv +1 more source
Annals of Oncology, 2015 BACKGROUND O(6)-methyl-guanine-methyl-transferase (MGMT) silencing by promoter methylation may identify cancer patients responding to the alkylating agents dacarbazine or temozolomide.
L. Barault +22 more
semanticscholar +1 more source
How do electronic carriers cross Si-bound alkyl monolayers? [PDF]
, 2005 Electron transport through Si-C bound alkyl chains, sandwiched between n-Si and Hg, is characterized by two distinct types of barriers, each dominating in a different voltage range. At low voltage, current depends strongly on temperature but not on molecular length, suggesting transport by thermionic emission over a barrier in the Si. At higher voltage,
arxiv +1 more source
Tunneling transport in devices with semiconducting leads [PDF]
Phys. Rev. B 81, 085307 (2010), 2009 This paper extends the modern theory of tunneling transport to finite temperatures. The extension enables applications to molecular electronic devices connected to semiconducting leads. The paper presents an application of the theory to molecular devices made of alkyl chains connected to silicon nano-wires, mapping their transport characteristics as ...
arxiv +1 more source
Ovarian reserve after treatment with alkylating agents during childhood.
Human Reproduction, 2015 STUDY QUESTION What is the effect of different alkylating agents used without pelvic radiation to treat childhood cancer in girls on the ovarian reserve in survivors?
C. Thomas-Teinturier +13 more
semanticscholar +1 more source
Cancer, 2015 The alkylating agents (ALKYs) streptozotocin, dacarbazine, and temozolomide currently are the main drugs used in systemic chemotherapy for neuroendocrine tumors (NETs).
A. Dussol +7 more
semanticscholar +1 more source
British Journal of Cancer, 2015 Background:O6-Methylguanine-DNA methyltransferase (MGMT) loss of expression has been suggested to be predictive of response to temozolomide in neuroendocrine tumours (NETs), but so far, only limited data are available.
Thomas Walter +14 more
semanticscholar +1 more source