Results 31 to 40 of about 587 (116)
Infection control in the brain and the eye
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester +2 more
wiley +1 more source
EHD4 and ASAP2 are critical negative regulators of the claudin‐5‐based endothelial barrier
Cell‐surface CLDN‐5 protein levels can be evaluated using a probe that can bind to the extracellular domains of CLDN‐5. A probe derived from Clostridium perfringens enterotoxin allows us to isolate cells with high CLDN‐5 protein levels from a knockout cell library.
Yosuke Hashimoto +8 more
wiley +1 more source
Comparative Analysis of Buckling-Restrained Braced Frames in Eccentric Configuration (BRBF-Es) and Eccentrically Braced Frames (EBFs) [PDF]
Continuing on the findings of “Using Buckling-Restrained Braced Frames in Eccentric Configuration,” by Dr. Gary S. Prinz, P.E., which determined that, from a performance standpoint, BRBF-Es could be a viable alternative for EBFs.
Vayda, Peter T
core +1 more source
Mapping Dental Care for Children and Adolescents With Rare Diseases: A Brazilian Multicentre Study
ABSTRACT Objectives To describe the landscape of dental care provided by specialised centres for children and adolescents with rare diseases (RDs) in the state of Minas Gerais, southeastern Brazil. Methods A retrospective cross‐sectional study was conducted involving individuals aged 0–18 years with a confirmed diagnosis of a RD who received care at ...
Heloisa Vieira Prado +21 more
wiley +1 more source
Statistical Analysis of Different Muon-antineutrino->Electron-antineutrino Searches
A combined statistical analysis of the experimental results of the LSND and KARMEN \numubnueb oscillation search is presented. LSND has evidence for neutrino oscillations that is not confirmed by the KARMEN experiment. This joint analysis is based on the
A. Aguilar +36 more
core +1 more source
Lipid Nanoparticles in Drug Delivery: Overcoming Challenges and Unlocking New Frontiers
Lipid nanoparticles (LNPs) have revolutionized nucleic acid delivery, yet challenges in formulation, stability, and targeted efficacy persist. This review explores how advances in microfluidic manufacturing, precision targeting, and endosomal escape are reshaping LNP design.
Jordan Kambanis +7 more
wiley +1 more source
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini +7 more
wiley +1 more source
Personalized Models of Biological Barriers and Their Diseases: Recent Progress with Organs‐On‐Chips
Buck and Bugter et al. explore the architectural diversity and physiological functions of human barrier systems and reveal how organ‐on‐chip platforms, particularly those integrating patient‐derived cells, are advancing barrier disease modeling. They highlight how emerging biological and technological advances can be used to bridge the gap between ...
Franziska Buck +4 more
wiley +1 more source
Buckling instability of web plastifying dampers: analytical and numerical approach [PDF]
This paper describes a numerical study on the instability of a brace-type seismic damper based on the out of plane yielding of the web of wide-flange steel sections (Web Plastifying Damper, WPD)The damper is intended to be installed in a framed ...
Benavent Climent, Amadeo +2 more
core
The environmental behavior and impact of anti‐corrosion nanoadditives, ZnAl‐NO2 and MgAl‐NO2 layered double hydroxides (LDH), are assessed under marine conditions. These nanomaterials show instability in water but exhibit no or low toxicity to most tested marine species.
Joana Figueiredo +12 more
wiley +1 more source

