Results 1 to 10 of about 1,121,623 (279)

Quality of life effects of androgen deprivation therapy in a prostate cancer cohort in New Zealand: Can we minimize effects using a stratification based on the aldo-keto reductase family 1, member C3 rs12529 gene polymorphism? [PDF]

open access: yes, 2016
Background: Androgen deprivation therapy (ADT) is an effective palliation treatment in men with advanced prostate cancer (PC). However, ADT has well documented side effects that could alter the patient's health-related quality of life (HRQoL).
Benjamin, Benji   +12 more
core   +2 more sources

Efficacy of treatment of extensive drug resistant tuberculosis in patients with different genotypes in the biotransformation enzyme genes of CYP2B6 and NAT2

open access: yesТуберкулез и болезни лёгких, 2020
The objective of the study: to evaluate the efficacy of treatment of extensive drug resistant tuberculosis (XDR-TB) in patients with different genotypes in the biotransformation system NAT2 (rs1041983, rs1799930, rs1799931, rs1801280) and CYP2B6 genes ...
M. M. Yunusbаevа   +5 more
doaj   +1 more source

Development of Single Nucleotide Polymorphism (SNP)-Based Triplex PCR Marker for Serotype-specific Escherichia coli Detection

open access: yesPathogens, 2022
Single-nucleotide polymorphisms (SNPs) are one of the most common forms of genetic variation and as such are powerful tools for the identification of bacterial strains, their genetic diversity, phylogenetic analysis, and outbreak surveillance.
Md-Mafizur Rahman   +2 more
doaj   +1 more source

An Allele Based-Approach for Internet of Transactional Things Service Placement in Intelligent Edge Environments

open access: yesIoT
The rapid expansion of the Internet of Things (IoT) has steered in a new generation of connectivity and data-driven decision-making across diverse industrial sectors. As IoT deployments continue to expand, the need for robust and reliable data management
Driss Riane   +2 more
doaj   +1 more source

Bw4 ligand and direct T-cell receptor binding induced selection on HLA A and B alleles

open access: yesFrontiers in Immunology, 2023
IntroductionThe HLA region is the hallmark of balancing selection, argued to be driven by the pressure to present a wide variety of viral epitopes. As such selection on the peptide-binding positions has been proposed to drive HLA population genetics. MHC
Reut Levi, Lee Levi, Yoram Louzoun
doaj   +1 more source

Lab Retriever: a software tool for calculating likelihood ratios incorporating a probability of drop-out for forensic DNA profiles. [PDF]

open access: yes, 2015
BackgroundTechnological advances have enabled the analysis of very small amounts of DNA in forensic cases. However, the DNA profiles from such evidence are frequently incomplete and can contain contributions from multiple individuals.
Cheng, Ken   +6 more
core   +1 more source

Allele Frequencies Database [PDF]

open access: yesTransfusion Medicine and Hemotherapy, 2014
This review describes a database for the collection, archiving, sorting, searching and display of gene and allele frequencies for immunogenetic genes.
Louise Y C, Takeshita   +3 more
openaire   +2 more sources

Identifikasi Genetik Menggunakan Marker Mikrosatelit dan Hubungannya dengan Sifat Kuantitatif pada Sapi

open access: yesMedia Peternakan, 2007
The occurrence of genetic changes in Bali and Brangus cattle crossing and it’s relationship to quantitative traits (e.g. growth and birth weight) were identified using microsatellite markers.
Maskur, Muladno, B. Tappa
doaj  

Association analysis between the C516T polymorphism in the 5-HT2A receptor gene and schizophrenia Análise de associação entre o polimorfismo C516T do gene do receptor 5-HT2A e esquizofrenia

open access: yesArquivos de Neuro-Psiquiatria, 2007
Data from epidemiological studies have demonstrated that genetics is an important risk factor for schizophrenia. Disturbances of serotonergic brain pathways have been implicated in the pathophysiology of schizophrenia.
Vivian Bertola   +4 more
doaj   +1 more source

Asymptotics of the allele frequency spectrum associated with the Bolthausen-Sznitman coalescent

open access: yes, 2007
We work in the context of the infinitely many alleles model. The allelic partition associated with a coalescent process started from n individuals is obtained by placing mutations along the skeleton of the coalescent tree; for each individual, we trace ...
Basdevant, Anne-Laure   +1 more
core   +5 more sources

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