Results 1 to 10 of about 1,022,437 (344)

Understanding Cancer Through the Lens of Epigenetic Inheritance, Allele-Specific Gene Expression, and High-Throughput Technology

open access: yesFrontiers in Oncology, 2019
Epigenetic information is characterized by its stable transmission during mitotic cell divisions and plasticity during development and differentiation. This duality is in contrast to genetic information, which is stable and identical in all cells in an ...
Maxwell P. Lee
doaj   +1 more source

Frequency changes in HLA‐I alleles: A marker to guide immunotherapy in lung adenocarcinoma patients and its relationship with tumor mutational burden and PD‐L1 expression

open access: yesThoracic Cancer, 2023
Background The aim of the study was to investigate differences in HLA‐I alleles between lung adenocarcinoma patients and healthy controls and determine their association with PD‐L1 expression and tumor mutational burden (TMB) to understand the mechanism ...
Xuanpeng Wu   +9 more
doaj   +1 more source

Use of allele specific PCR to investigate the presence of β-casein polymorphism in Holstein-Friesian cows [PDF]

open access: yesVeterinarski Glasnik, 2022
Following the “one health” principle, we have conducted optimization of a protocol for β-casein genotyping in cattle in order to select cows with exclusively the A2A2 genotype.
Ristanić Marko   +6 more
doaj   +1 more source

HLA-A and -B alleles and haplotypes in hemochromatosis probands with HFE C282Y homozygosity in central Alabama

open access: yesBMC Medical Genetics, 2002
Background We wanted to quantify HLA-A and -B allele and haplotype frequencies in Alabama hemochromatosis probands with HFE C282Y homozygosity and controls, and to compare results to those in other populations.
Barton James C, Acton Ronald T
doaj   +1 more source

Polymorphism study of HLA-A, B, DRB1 alleles in patients with chronic renal failure, in Shandong Peninsula

open access: yesZhongguo shuxue zazhi, 2022
Objective To investigate the association between HLA-A, B, DRB1 alleles and chronic renal failure (CRF) in Han population of Shandong Peninsula. Methods Sequence specific oligonucleotide probe-polymerase chain reaction (PCR-SSO) was used to genotype 880 ...
Rong WANG   +5 more
doaj   +1 more source

Results of conducting the primary seed production using the method of electrophoresis in the FSBSI “ARC “Donskoy

open access: yesЗерновое хозяйство России, 2022
The current paper has presented the study and estimation results of winter bread wheat varieties in primary seed production (2019-2021) based on the method of electrophoresis.
T. I. Firsova   +3 more
doaj   +1 more source

Relationship between grain colour and preharvest sprouting-resistance in wheat Relação entre cor de grão e resistência à germinação pré-colheita em trigo

open access: yesPesquisa Agropecuária Brasileira, 2005
Since red alleles (R) of the genes that control grain colour are important for the improvement of preharvest sprouting resistance in wheat and there are three independently inherited loci, on chromosomes 3A, 3B and 3D of hexaploid wheat, it is possible ...
Manoel Carlos Bassoi, John Flintham
doaj   +1 more source

HLA-A*11:01:01:01, HLA-C*12:02:02:01-HLA-B*52:01:02:02, Age and Sex Are Associated With Severity of Japanese COVID-19 With Respiratory Failure

open access: yesFrontiers in Immunology, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus causing coronavirus disease 2019 (COVID-19) was announced as an outbreak by the World Health Organization (WHO) in January 2020 and as a pandemic in March 2020.
Seik-Soon Khor   +12 more
doaj   +1 more source

Advances in the genetic basis of ischemic stroke [PDF]

open access: yesJournal of Medical Biochemistry, 2008
As one of the leading causes of death within both the developed and developing world, stroke is a worldwide problem. About 80% of strokes are ischemic. It is caused by multiple genetic factors, environmental factors, and interactions among these factors.
Stanković Sanja, Majkić-Singh Nada
doaj  

Genome-Wide Association Study for Chronic Hepatitis B Infection in the Thai Population

open access: yesFrontiers in Genetics, 2022
To identify novel host genetic variants that predispose to hepatitis B virus (HBV) persistence, we performed the first genome-wide association study in the Thai population involving 318 cases of chronic hepatitis B and 309 healthy controls after quality ...
Saeideh Ashouri   +20 more
doaj   +1 more source

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