Results 1 to 10 of about 1,186,851 (331)

Invasive Allele Spread under Preemptive Competition

, 2005
We study a discrete spatial model for invasive allele spread in which two alleles compete preemptively, initially only the "residents" (weaker competitors) being present.
A. Gandhi, A.N. Kolmogorov, A.N. Kolmogorov, D. ben-Avraham, D.E. Taneyhill, D.W. Yu, G. Korniss, H.L. Richards, H.M. Duiker, J.B. Shurin, J.D. Murray, L. O’Malley, M. Avrami, M. Karttunen, P. Amarasekare, P.A. Rikvold, R.A. Fisher, R.A. Ramos, W._.A. Johnson, Y. Ishibashi   +19 more
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Disparities in allele frequencies and population differentiation for 101 disease-associated single nucleotide polymorphisms between Puerto Ricans and Non-Hispanic Whites [PDF]

, 2009
BACKGROUND. Variations in gene allele frequencies can contribute to differences in the prevalence of some common complex diseases among populations. Natural selection modulates the balance in allele frequencies across populations.
Adiconis, Xian, Arnett, Donna, Demissie, Serkalem, Garcia-Bailo, Bibiana, Lai, Chao-Qiang, Mattei, Josiemer, Ordovas, Jose M., Parnell, Laurence D., Shen, Jian, Tucker, Katherine L.   +9 more
core   +3 more sources

Development of Single Nucleotide Polymorphism (SNP)-Based Triplex PCR Marker for Serotype-specific Escherichia coli Detection

Pathogens, 2022
Single-nucleotide polymorphisms (SNPs) are one of the most common forms of genetic variation and as such are powerful tools for the identification of bacterial strains, their genetic diversity, phylogenetic analysis, and outbreak surveillance.
Md-Mafizur Rahman, Sang-Jin Lim, Yung-Chul Park   +2 more
doaj   +1 more source

Exome sequencing identifies nonsegregating nonsense ATM and PALB2 variants in familial pancreatic cancer. [PDF]

, 2013
We sequenced 11 germline exomes from five families with familial pancreatic cancer (FPC). One proband had a germline nonsense variant in ATM with somatic loss of the variant allele. Another proband had a nonsense variant in PALB2 with somatic loss of the
Al-Sukhni, Wigdan, Borgida, Ayelet E, Gallinger, Steven, Grant, Robert C, Holter, Spring, Kanji, Zaheer S, McPherson, John D, McPherson, Treasa, Peltekova, Vanya, Serra, Stefano, Stein, Lincoln D, Trinh, Quang M, Whelan, Emily   +12 more
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Bw4 ligand and direct T-cell receptor binding induced selection on HLA A and B alleles

Frontiers in Immunology, 2023
IntroductionThe HLA region is the hallmark of balancing selection, argued to be driven by the pressure to present a wide variety of viral epitopes. As such selection on the peptide-binding positions has been proposed to drive HLA population genetics. MHC
Reut Levi, Lee Levi, Yoram Louzoun
doaj   +1 more source

Non-equilibrium theory of the allele frequency spectrum [PDF]

, 2006
A forward diffusion equation describing the evolution of the allele frequency spectrum is presented. The influx of mutations is accounted for by imposing a suitable boundary condition.
Evans, Steven N., Shvets, Yelena, Slatkin, Montgomery   +2 more
core   +2 more sources

Genome-wide Identification and Functional Analyses of the 5-O-Glucosyltransferase Family Reveal Its Potential Roles in Anthocyanidin Diglucosides Synthesis of Grape Skins with Vitis amurensis Pedigree

Journal of the American Society for Horticultural Science
Vitis amurensis grape cultivars and hybrids are mainly used to make wines in Northeast Asia with a cold winter. Anthocyanidin glucosylation at 5-O position catalyzed by 5-O-glucosyltransferase (5GT) in grape skins is crucial for color stability of red ...
Lei Zhu, Yunhua Chen, Yunqing Liu, Dandan Li, Yiming Yang, Yuanyuan Wang, Yunting Liu, Mingjie Wang, Jingyu Xu, Xixi Hu   +9 more
doaj   +1 more source

Molecular Identification of Bacillus Isolated from Korean Water Deer (Hydropotes inermis argyropus) and Striped Field Mouse (Apodemus agrarius) Feces by Using an SNP-Based 16S Ribosomal Marker

Animals, 2022
Ambiguous, heterogeneous, endospore-forming Bacillus species, notably Bacillus cereus, often produce fatal toxins that threaten human health. We identified Bacillus from wild animal fecal samples (n = 80), including the Korean water deer (n = 25) and ...
Md-Mafizur Rahman, Sang-Jin Lim, Yung-Chul Park   +2 more
doaj   +1 more source

MONOAMINE OXIDASE A (MAOA), CHILDHOOD TRAUMA, ALCOHOLISM AND AGGRESSION [PDF]

, 2008
Women who have experienced childhood sexual abuse (CSA) have an increased risk of alcoholism and antisocial personality disorder (ASPD). Among males, a functional polymorphism (MAOA-LPR, monoamine oxidase A linked polymorphic region) in the promoter ...
DUCCI, FRANCESCA
core  

Artificial escape from XCI by DNA methylation editing of the CDKL5 gene. [PDF]

, 2020
A significant number of X-linked genes escape from X chromosome inactivation and are associated with a distinct epigenetic signature. One epigenetic modification that strongly correlates with X-escape is reduced DNA methylation in promoter regions. Here,
Anderson, Johnathon D, Buchanan, Fiona KB, Cameron, David, Carter, Jasmine L, Coggins, Nicole B, Deng, Peter, Fink, Kyle D, Gonzalez, Casiana E, Halmai, Julian ANM, Halmai, Julian ANM, Lock, Samantha R, Nolta, Jan, O'Geen, Henriette, Segal, David J, Waldo, Jennifer J   +14 more
core   +1 more source